Tarceva erlotinib patients
Common Questions and Answers about Tarceva erlotinib patients
tarceva
both lung plumonory nodul ans one large tumor ,after 6 cycle of chemo with TAXOL,CARBOPLATIN ,AND COMBINED with erlotinib .since then the diesies showed improvment and shrinkage in tumor. . HE has been under maintance treatment with Tarceva since 2009 upto now. the previous PET-CT ON JULY 2011 WAS NEGATIVE AND CONCLUSION was that no evidence of residual hypermetabolic disease seen in lung.. but the recent CT showed smal new lesion 1,8 *2 cm. in comparison to previous.
Edema (fluid accumulation in any body part, resulting in swelling) has been reported as an adverse event in 37% of pancreatic cancer patients taking Tarceva, although this side effect has not been reported in lung cancer cases.
However, the type of edema associated with Tarceva use is either generalized or involves a swelling of both legs. Swelling in only one leg may not be due to this drug. Unilateral leg swelling may be due to a local infection (cellulitis) in that area.
Asians, women, non-smokers, and those with adenocarcinoma histology. This drug still has been found to benefit males, smokers, and those with squamous cell histology, but to a lesser extent.
m doing research as quickly as I can to help she and her husband make an informed decision about what to do...if anything. The local drs are recommending 4 weeks of full brain radiation followed by tarceva. Prior to the finding the mets, they were planning 6 weeks of radiation to the right lung in combination with etoposide and cisplatin.
I'd appreciate any feedback. My thanks in advance to all responses....
Thanks for your response. To clarify: his treatment was adjunctive. At the time they saw no sign of cancer outside the lung. Now, however, after 4 rounds of chemotherapy the disease seems to have spread during treatment with taxotere and cisplatin: it's now in the liver, bones and adrenal glands. His original tumor was EGFR positive that is why Tarceva came up as a viable second step.
She has done very well with chemo and radiation until recently. She was started on Tarceva about 3 weeks ago. Recently, she has been experiencing a lot of confusion. I cannot find anywhere that this is a side effect of Tarceva (it is the only drug she is on at this time). Is it possible that she has a brain metastases? If not, what are the likely causes.
how can i get doctor to prescribe tarceva for inoperable lung cancer with secondary brain cancer has recieved one chemo session for lung then 5 radiotherapy for brain...help??????
There are particular subtypes of lung cancer which may have a better response with this drug (and non-smokers seem to benefit from it more than the smokers) . There are patients who improve with symptoms on erlotinib (such as cough), however, extending survival may not be achievable on the average. There are a few who would have a dramatic response and may be able to regain much more in the way of daily activities.
Radiation is usually advised for patients who are not fit to undergo an operation. The key words here are selected (selected patients) and individualized (individualized approach). This highlights the fact that there is an advantage, but the intervention is not for everybody.
The decision is not simply, let’s do it, there is an evaluation about how much lung to be removed and whether or not it can be tolerated.
My husband was diagnosed with a Pancoast tumor on his lung. He went thru chemo/ radiation and finally had surgery to remove the tumor. It was successful. He had more chemo for precaution. After one year, the cancer came back into his Adrenal Gland. It is also in his Lymph Nodes. They put him on Tarceva( a pill he took everyday) And after 6-7 weeks, he had tests done which showed it didn't do anything.. the tumor has grown. They said there is no other options..
The pain i get daily is from my chemo medicine, Tarceva. Along with some other side effects. Losing my hair was bad enough but putting on 20lbs killed me! not really :-\ Anyway, its nice to know i have people out there who really care. I wish there was one of these sites for cancer patients. There probably is but im rarely on the computer. If any of you all are interested, my sister put up a website for me called Gina's Angels. It talks about how im doing and shows pictures and stuff.
He has been through several chemo and radiation treatments and is now starting on Tarceva. It has been a long road so far and he has his good days and bad days. I don't think there's any way even the doctors can tell us how much time they have left specifically. His doctor said it could be a year, 5 or even 10, but of course we are all hoping and praying for at least 20 more with him.
It has already spread to the spine, both lungs and the lymph system. Doctors triede Tarceva for 3 weeks but her body had a very bad reaction. For the spine they did radiotherapy. But since she was diagnose 3 months ago she has lost aalmost her voice. she is using oxygen for the major part of the day but doctors don't wan't to talk about time. no more medes will be given and she was reffer to hospice....
Oh my God! Thank you Lord for letting me hear from someone with darn near my situation!
I had lower left lobectomy May 29, 2009. Stage 1A BAC (nodule 1.3 cm)...no chemo (there seems to be only one that "might" work, Tarceva) and no radiation (what will they burn out? the lobe's gone already).
90 % "chance" of making 5 years is what they tell me. Mucho NO info on BAC. Only bad prognosis.
I have already survived breast cancer (BRCA 2 Mutation) for 6 YEARS!
The importance is that by and large, 2 drugs are recommended for patients who are deemed well enough to aim for extending survival. You asked in the other post about the chances of making it til June, if she is receiving only 1 drug, and is pretty much in bed more than half of her waking hours - the goal of treatment may be to improve symptom control - not really halting cancer progression. If this is the case, her chances would be less.
Stay positive.
Average survival may only be around 9 to 12 months, but there are some patients (about 20%) who may reach the 2 year mark. This of course, is only a question of length of time. What is more important is that the goals of treatment would be to improve qualityof life. Hence, if the treatment seems to be making things much worse, then it would be time to change the treatment.
He started Tarceva this January but it seems it did not work as the cancer spread to brain…. 9 mets were identified in the initial MRI 2 weeks ago but the subsequent MRI right before yesterday’s gamma knife procedure (which removed 7 mets) evidenced numerous other tiny/small tumors spread all over the brain….He has been in relatively good condition (eating well, no weight loss) until these new mets emerged (which affected his walking and reading ability)….
In lung cancer, there are assays for quantitative testing of epidermal growth factor receptors (EGFR), which confers sensitivity to some drugs used in lung cancer like Iressa or Tarceva. The cost of testing can range from a few hundred dollars (e.g. ER/ PR assays) to around 3800 dollars for the Oncotype DX test.
In 2005, he had Tarceva. In 2008 they discovered metastasis to the liver (3 lesions) and he underwent chemo again (I think Avastin) and he finished the treatment in March. The doctor said the tumors in both the lungs and liver were smaller.
For the past 3 weeks he´s been vomiting, but sporadically. There is no pattern. It doesn´t matter if he eats lightly or heavily. Some days he vomits once, some days nothing.
He went to see a Gastroenterologist. They did a sonogram...
Hi, My 69 year old Dad has stage 4 Lung nsc cancer that he has been battling for over 2 years with good results from first Tarceva, then Chemo and prior to that radiation to mets to his brain. He is an otherwise healthy, robust, nonsmoking person. Last month he started experiencing problems walking, nausea and headaches. He was referred to a Neurologist who recommended a Shunt to help regulate the fluid in his brain. It has been a nightmare ever since.
She is not a candidate for treatment and is refusing even palliative tx such as Tarceva. PET Scan showed no evidence of cancer in brain, liver or bone. Because she is experiencing no symptoms she is hesistant to participate in a home hospice program. What symptoms are generally experienced and if possible a general timeline for disease progression.
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