i wouldnt lower the tacrolimus dose further
The specialist reviewed all of the options with us - cyclosporine, pilocarpine or tacrolimus with sirolimus. She said that very rarely has she seen any dog respond to cyclosporine after not responding to tacrolimus. She also said that because our dog doesn't have a dry, goopy nose, that pilocarpine wouldn't be a first choice. She recommended a mix of tacrolimus with sirolimus. She said sirolimus is new. I have not been able to find anything about this drug on the internet.
His cretanine is almost 1.4 or around. My question is that should he continue his TACROLIMUS tablets or should switch to some other tablets which are safe for kidneys?
Secondly , in my sorrounding there is an opinion that lowering the TACROLIMUS dose also let the liver enzymes to increase? Do you favour such opinions as my father has lowered his tacrolimus dose to keep his kidneys safe?
Sir ,will wait for your kind reply.
Thanks.
s hard to perform my job or other daily tasks when my eyelids are so inflamed. I guess steroids are the only option until they develop something better. Is Tacrolimus a promising nonsteroidal option?
The treatments of this condition are application of topical corticosteroids (betamethasone, clobatesol, flucinolone) which will reduce the inflammatory process. Topical immunomodulators like pimecrolimus and tacrolimus can be used in severe conditions.
I hope it helps. It is very difficult to precisely confirm a diagnosis without examination and investigations and the answer is based on the medical information provided. For exact diagnosis, you are requested to consult your doctor.
Hormonal contraceptives such as the pill and the patch may increase the blood level of tacrolimus. Tacrolimus may also reduce the effectiveness of these hormonal contraceptives. For this reason women who could get pregnant should ideally use a non-hormonal method of contraception, eg condoms, to prevent pregnancy while taking this medicine. Seek advice from your doctor or pharmacist.
there are prograf assistance programs that the company offers. If this is not feasible than using other cheaper medications such as verapamil for example for HTN for example will alllow much lower doses of prograf to be used (it delays metabolism of the medication) and thus it comes out cheaper.
AS I HAVE SUFFERED BREATHLESSNESS AND WALKING PROBLEMS,I HAVE BEEN TAKEN OFF TACROLIMUS AND PUT ON NEORAL-YET THERE IS NO IMPROVEMENT IN MY CONDITION.IS THERE ANY OTHER ANTI REJECTION DRUG THAT YOU WOULD RECOMMEND (I HAVE HAD A LIVER TRANSPLANT RECENTLY)? IN YOUR EXPERIENCE,CAN MY SITUATION BE IMPROVED?THANKS.
i would be extremely cautious about using it until more data is available especially since its purported effects on tacrolimus and cyclosporine metabolism are extreme. i am quite confident that there will be clinical trials coming down the road extremely soon.
We changed to the gel form of Genteal and Tacrolimus. The vet said he would drink more and he did. She recommended surgery for the first time. Casper has been her patient for 2+ years and she had never even suggested that there was a surgical solution. Within a week my dog was worse. I used saline soltion to clean his eyes. The next day he wouldn't pen his eyes. I put the solution in my own eye and discovered it wasn't fresh.
My tacrolimus level is 4.2 after 4 months of liver transplant, Is it dangerous? what should i do?
Most referral or veterinary teaching hospitals , or veterinary schools have veterinary opthalmolgists. Ask your vet for a referral to one in your area. Don't be afraid, just explain to him that you do not want to happen with your other pug to happen to her. If are still uncomfortable with this you can search your self online at: American College of Veterinary Opthalmologists, or the American Society of Veterinary Opthalmologists (http://www.asvo.org/). Good Luck!
i want to apply for NATIONAL VETERINARY EXAM so plz help me wt kind books i will need to prepare................. plzzzzzzzzzzzzzz helpppppppppppp meeeeeeeeeeeeee.
It has been shown that veterinary acupuncture in conjunction with anti-inflammatories (steroids) and analgesics (tramadol and others) is highly effective and may be more helpful than anti-inflammatories and analgesics alone. If surgery is not recommended, or if you choose not to have surgery performed, than acupuncture is worth a try.
Treatment is by topical steroids or oral therapy of corticosteroids in severe cases. Topical creams like tacrolimus ointment (Protopic) and pimecrolimus cream (Elidel) are also useful.
If still the symptoms do not improve then please get a clinical examination done by a dermatologist.
I hope it helps. Take care and please do keep me posted in case you have any additional doubts. Kind regards.
The reason may be infection, or something more serious, and veterinary exam is needed to see what the swellings are. An allergic reaction is unlikely, since allergic reactions usually cause a swollen face/muzzle or hives. As long as he is eating, drinking and breathing normally, then it can probably wait until Monday, when your regular veterinarian is open. You can also look online for low cost veterinary clinics in your area.
nothing much is being said in forums dedicated to veterinarians at this time. Also, I have personally contacted a toxicologist, a veterinary internist, a veterinary oncologist and a veterinary nutritionist and none of them have given me any evidence that this should be a concern.
The best source of information about your pet's nutrition and its affect on the pet is your veterinarian.
Dogs with fleas or allergies commonly scratch and traumatize themselves, creating a secondary bacterial skin infection/rash that makes the itch worse, and this is something that needs veterinary care. If skin infection is present, it is treated with antibiotics for 3-4 weeks and mild antibacterial shampoos.
Not the right place for this question. Sorry.
Whether he has bloat or the other problem that I suspect, which is disk disease (spinal disease) he would require veterinary attention since they are both very serious and may require medications or other therapies, such as surgery.
I don't know where you are writing from but in the States you could apply at most veterinary offices or online for a Care Credit Card. which is a low to no interest credit card that can only be used for medical, dental, or veterinary bills.
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