prograf can cause tremor and high blood pressure. its not unusual to feel fatigued this soon after a transplant.
i wouldnt lower the tacrolimus dose further
Hormonal contraceptives such as the pill and the patch may increase the blood level of tacrolimus. Tacrolimus may also reduce the effectiveness of these hormonal contraceptives. For this reason women who could get pregnant should ideally use a non-hormonal method of contraception, eg condoms, to prevent pregnancy while taking this medicine. Seek advice from your doctor or pharmacist.
More frequent aFib episodes, yet found to be hypertensive on 18-hour continuous BP study in neighborhood of 160/85 average when in sinus, lower BP when in Fib. Symptomatic in that exercise tolerance is significantly less when in Fib, also with constant chest "heaviness" and mild breathlessness.
Wish to control the arrhythmia which started ~ 6 mos ago and is now recurring once/week usually while asleep, and suspect that it is of parasympathetic character.
The specialist reviewed all of the options with us - cyclosporine, pilocarpine or tacrolimus with sirolimus. She said that very rarely has she seen any dog respond to cyclosporine after not responding to tacrolimus. She also said that because our dog doesn't have a dry, goopy nose, that pilocarpine wouldn't be a first choice. She recommended a mix of tacrolimus with sirolimus. She said sirolimus is new. I have not been able to find anything about this drug on the internet.
His cretanine is almost 1.4 or around. My question is that should he continue his TACROLIMUS tablets or should switch to some other tablets which are safe for kidneys?
Secondly , in my sorrounding there is an opinion that lowering the TACROLIMUS dose also let the liver enzymes to increase? Do you favour such opinions as my father has lowered his tacrolimus dose to keep his kidneys safe?
Sir ,will wait for your kind reply.
Thanks.
s hard to perform my job or other daily tasks when my eyelids are so inflamed. I guess steroids are the only option until they develop something better. Is Tacrolimus a promising nonsteroidal option?
The treatments of this condition are application of topical corticosteroids (betamethasone, clobatesol, flucinolone) which will reduce the inflammatory process. Topical immunomodulators like pimecrolimus and tacrolimus can be used in severe conditions.
I hope it helps. It is very difficult to precisely confirm a diagnosis without examination and investigations and the answer is based on the medical information provided. For exact diagnosis, you are requested to consult your doctor.
there are prograf assistance programs that the company offers. If this is not feasible than using other cheaper medications such as verapamil for example for HTN for example will alllow much lower doses of prograf to be used (it delays metabolism of the medication) and thus it comes out cheaper.
AS I HAVE SUFFERED BREATHLESSNESS AND WALKING PROBLEMS,I HAVE BEEN TAKEN OFF TACROLIMUS AND PUT ON NEORAL-YET THERE IS NO IMPROVEMENT IN MY CONDITION.IS THERE ANY OTHER ANTI REJECTION DRUG THAT YOU WOULD RECOMMEND (I HAVE HAD A LIVER TRANSPLANT RECENTLY)? IN YOUR EXPERIENCE,CAN MY SITUATION BE IMPROVED?THANKS.
i would be extremely cautious about using it until more data is available especially since its purported effects on tacrolimus and cyclosporine metabolism are extreme. i am quite confident that there will be clinical trials coming down the road extremely soon.
It happened at the same time that I had renewed my synthroid so I had a new bottle and I wondered if it could inadvertantly be the wrong dose. Is tremor like this one of the signs something is amiss with my thyroid.
This sounds like essential tremor, which a neurological disorder is causing involuntary shaking of particular body parts, head and hands. These tremors worsen when hands are used rather than when resting. It may affect the voice making it quivering. Usually the cause is unknown, without a known cure. It is different from parkinson’s disease. parkinson’s involves involuntary tremors at rest, muscle stiffness, slowness of movement and is caused by deficiency of dopamine in brain.
My tacrolimus level is 4.2 after 4 months of liver transplant, Is it dangerous? what should i do?
Women are more likely to develop the head tremor than are men.Other types of tremor may also occur, including postural tremor of the outstretched arms, intentional tremor of the arms and rest tremor in the arms.
a variety of non-motor features have recently been linked with ET. These include anxiety and depressive symptoms as well as cognitive difficulty.
Recent studies have demonstrated that late-onset ET (onset > age 65) may be associated with an increased risk of developing dementia.
This tremor occurs when a person ends a purposeful movement (such as pressing a button) or aims for a target (as when reaching for an object with the hand). The person may miss the targeted object because of the tremor. Intention tremors are relatively slow and coarse.
These tremors may result from damage to the cerebellum or its connections. Thus, cerebellar tremors and intention tremors may be used synonymously. Multiple sclerosis is a common cause.
Treatment is by topical steroids or oral therapy of corticosteroids in severe cases. Topical creams like tacrolimus ointment (Protopic) and pimecrolimus cream (Elidel) are also useful.
If still the symptoms do not improve then please get a clinical examination done by a dermatologist.
I hope it helps. Take care and please do keep me posted in case you have any additional doubts. Kind regards.
Thanks for using the forum. I am happy to address your questions, and my answer will be based on the information you provided here. Please make sure you recognize that this forum is for educational purposes only, and it does not substitute for a formal office visit with your doctor.
It sounds like you have been suffering from achiness in your arms and legs and a tremor particularly when you are trying to hold something.
For example, parkinsonism, such as what you are asking, has a resting tremor that is termed “pill-rolling” tremor. The tremor is typically one sided initially. Other types of tremors include essential tremor (which is a tremor with many different postures/actions), orthostatic tremor, enhance physiologic tremor, etc.
Everyone has a tremor but for most, it is not noticeable unless there is stress, caffeine, anxiety. This is the enhanced physiological tremor.
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