i wouldnt lower the tacrolimus dose further
The specialist reviewed all of the options with us - cyclosporine, pilocarpine or tacrolimus with sirolimus. She said that very rarely has she seen any dog respond to cyclosporine after not responding to tacrolimus. She also said that because our dog doesn't have a dry, goopy nose, that pilocarpine wouldn't be a first choice. She recommended a mix of tacrolimus with sirolimus. She said sirolimus is new. I have not been able to find anything about this drug on the internet.
It is a autoimmune disease having an abnormally low platelet count (thrombocytopenia) of unknown origin. It occurs in children as well as adults. Peak prevalence occurs in adults aged 20-50 years. Peak prevalence occurs in children aged 2-4 years. Approximately 40% of all patients are younger than 10 years. as adults.
Low platelet count (Thrombocytopenia) can be a side effect of HCV treatment drugs. Especially peg-interferon. Thrombocytopenia is also a complication of cirrhosis of the liver.
Secondary thrombocytopenia is treated by eliminating the cause. Primary thrombocytopenia is treated by immunosuppressive therapies, such as prednisone, which your dog is currently on. Right now we do not know whether your dog has primary or secondary thrombocytopenia, that is why your vet has tried treating with both an antibiotic and with prednisone.
His cretanine is almost 1.4 or around. My question is that should he continue his TACROLIMUS tablets or should switch to some other tablets which are safe for kidneys?
Secondly , in my sorrounding there is an opinion that lowering the TACROLIMUS dose also let the liver enzymes to increase? Do you favour such opinions as my father has lowered his tacrolimus dose to keep his kidneys safe?
Sir ,will wait for your kind reply.
Thanks.
s hard to perform my job or other daily tasks when my eyelids are so inflamed. I guess steroids are the only option until they develop something better. Is Tacrolimus a promising nonsteroidal option?
The treatments of this condition are application of topical corticosteroids (betamethasone, clobatesol, flucinolone) which will reduce the inflammatory process. Topical immunomodulators like pimecrolimus and tacrolimus can be used in severe conditions.
I hope it helps. It is very difficult to precisely confirm a diagnosis without examination and investigations and the answer is based on the medical information provided. For exact diagnosis, you are requested to consult your doctor.
your weakness and weight gain will begin to resolve once you stop receiving IVIG and steroids. These medications will only stop when you stop having episodes of thrombocytopenia. The thrombocytopenia will hopefully resolve once the tumor starts responding to the chemotherapy.
Hormonal contraceptives such as the pill and the patch may increase the blood level of tacrolimus. Tacrolimus may also reduce the effectiveness of these hormonal contraceptives. For this reason women who could get pregnant should ideally use a non-hormonal method of contraception, eg condoms, to prevent pregnancy while taking this medicine. Seek advice from your doctor or pharmacist.
there are prograf assistance programs that the company offers. If this is not feasible than using other cheaper medications such as verapamil for example for HTN for example will alllow much lower doses of prograf to be used (it delays metabolism of the medication) and thus it comes out cheaper.
AS I HAVE SUFFERED BREATHLESSNESS AND WALKING PROBLEMS,I HAVE BEEN TAKEN OFF TACROLIMUS AND PUT ON NEORAL-YET THERE IS NO IMPROVEMENT IN MY CONDITION.IS THERE ANY OTHER ANTI REJECTION DRUG THAT YOU WOULD RECOMMEND (I HAVE HAD A LIVER TRANSPLANT RECENTLY)? IN YOUR EXPERIENCE,CAN MY SITUATION BE IMPROVED?THANKS.
Hi, I'm new to this site
I would appreciate any information about marginal zone lymphoma (MZL) secondary to HepC infection?
My partner was diagnosed with MZL in Jan 08 by surgical biopsy of a lymph node in his neck. It's a rare indolent form & most likely results from HepC infection. He has a small patch in the bone but CT scans & a PET scan revealed no other nodes in between, so is sort of stage 1 & 4 at the same time.
He is 56yrs old, geno 1b, +ive for over 30 yrs.
Has anyone tried to supplement your Doggy with papaya leaf extract to help raise their platelets? My dog is diagnosed with immune mediated Thrombocytopenia which means his platelets is down to like zero and many bruises on him. He's been on Pred for a wk to help increase Plt but it's working slowly. I read a review at this website herbal papaya that she used on her dog n works. I would like to know if there's more info about this papaya leaf extract.
If for any reason your blood platelet count falls below normal, the condition is called thrombocytopenia. Normally, you have anywhere from 150,000 to 450,000 platelets per microliter of circulating blood. Because each platelet lives only about 10 days, your body continually renews your platelet supply by producing new platelets in your bone marrow.
Thrombocytopenia has many possible causes.
i would be extremely cautious about using it until more data is available especially since its purported effects on tacrolimus and cyclosporine metabolism are extreme. i am quite confident that there will be clinical trials coming down the road extremely soon.
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