i would be extremely cautious about using it until more data is available especially since its purported effects on tacrolimus and cyclosporine metabolism are extreme. i am quite confident that there will be clinical trials coming down the road extremely soon.
Prevention is key, but therapeutic treatment of hypertrophic scars and keloids includes occlusive dressings, compression therapy, intralesional corticosteroid injections, cryosurgery, excision, radiation therapy, laser therapy, interferon therapy, 5-fluorouracil (5-FU), doxorubicin, bleomycin, verapamil, retinoic acid, imiquimod 5% cream, tamoxifen, tacrolimus, botulinum toxin, and other promising therapies such as transforming growth factor (TGF)–beta3, and recombinant human (rh) interleukin
i wouldnt lower the tacrolimus dose further
Other therapy with topical calcipotriene, tacrolimus 0.1% ointment (under occlusion) and imiquimod 5% cream may also be useful. PUVA and photodynamic therapy is also found to be useful.
You can consult any good dermatologist in your area or in the metro cities and discuss these treatment options with him.
It is very difficult to precisely confirm a diagnosis without examination and investigations and the answer is based on the medical information provided.
Cheilitis(Inflammation of the skin on and around the lips)is often seen in atopic dermatitis. Treatment is by topical steroids or oral therapy of corticosteroids in severe cases. Topical creams like tacrolimus ointment (Protopic) and pimecrolimus cream (Elidel) are also useful.
If still the symptoms do not improve then please get a clinical examination done by a dermatologist.
I hope it helps. Take care and please do keep me posted in case you have any additional doubts. Kind regards.
Tinea versicolor is the commonest cause of white patches.Antihistaminics, topical steroids, PUVA therapy, retinoic acid and tacrolimus are the available treatment options for lichen planus.It is best to clarify your doubts by your dermatologist. I hope it helps.
Take care and regards!
The specialist reviewed all of the options with us - cyclosporine, pilocarpine or tacrolimus with sirolimus. She said that very rarely has she seen any dog respond to cyclosporine after not responding to tacrolimus. She also said that because our dog doesn't have a dry, goopy nose, that pilocarpine wouldn't be a first choice. She recommended a mix of tacrolimus with sirolimus. She said sirolimus is new. I have not been able to find anything about this drug on the internet.
- Exposure of affected skin to intense ultraviolet light, such as narrow-band UVB
- Medicines taken by mouth such as trimethylpsoralen (Trisoralen)
- Medicines that she applied to her skin such as (Corticosteroid creams, immunosuppressants such as pimecrolimus (Elidel) and tacrolimus (Protopic),repigmenting agents such as methoxsalen (Oxsoralen)).
She also tried some herbal options.
Even though her vitiligo did not go away it improved significantly. It also stabilized and stopped spreading.
Cheilitis(Inflammation of the skin on and around the lips)is often seen in atopic dermatitis. Treatment is by topical steroids or oral therapy of corticosteroids in severe cases.Topical creams like tacrolimus ointment (Protopic) and pimecrolimus cream (Elidel) are also useful. Till then keep your lips well moisturized.
It is very difficult to precisely confirm a diagnosis without examination and investigations and the answer is based on the medical information provided.
Diagnosed by blood test like RAST. Treatment is by topical steroids or oral therapy of corticosteroids in severe cases. Topical creams like tacrolimus ointment (Protopic) and pimecrolimus cream (Elidel) are also useful.
I hope it helps. Take care and regards.
His cretanine is almost 1.4 or around. My question is that should he continue his TACROLIMUS tablets or should switch to some other tablets which are safe for kidneys?
Secondly , in my sorrounding there is an opinion that lowering the TACROLIMUS dose also let the liver enzymes to increase? Do you favour such opinions as my father has lowered his tacrolimus dose to keep his kidneys safe?
Sir ,will wait for your kind reply.
Thanks.
s hard to perform my job or other daily tasks when my eyelids are so inflamed. I guess steroids are the only option until they develop something better. Is Tacrolimus a promising nonsteroidal option?
The treatments of this condition are application of topical corticosteroids (betamethasone, clobatesol, flucinolone) which will reduce the inflammatory process. Topical immunomodulators like pimecrolimus and tacrolimus can be used in severe conditions.
I hope it helps. It is very difficult to precisely confirm a diagnosis without examination and investigations and the answer is based on the medical information provided. For exact diagnosis, you are requested to consult your doctor.
The protocol at my institution is to stop tacrolimus on Day 1 of protease inhibitor therapy and measure tacrolimus levels 3 and 7 days later, and then adjust the dose of tacrolimus according to the level. At least in the small number of patients we have seen, a tacrolimus dose of 0.5 mg once per week is sufficient to maintain a drug level of 3–5 ng/mL.
ve been using Aquaphor Healing Ointment (Advanced therapy) for two weeks now and my skin is trying to heal and close up so it can be soft but since my mouth is moving all the time it makes the cracks deeper and now it burns whenever water or any liquid touches it, so now I'm done using the ointment seeing as it is just making it worse. Please tell me what it is and any treatments or home remedies that can help it go away.
Treatment is by topical steroids or oral therapy of corticosteroids in severe cases. Topical creams like tacrolimus ointment (Protopic) and pimecrolimus cream (Elidel) are also useful.
I hope it helps. Take care and please do keep me posted in case you have any additional doubts. Kind regards.
Hormonal contraceptives such as the pill and the patch may increase the blood level of tacrolimus. Tacrolimus may also reduce the effectiveness of these hormonal contraceptives. For this reason women who could get pregnant should ideally use a non-hormonal method of contraception, eg condoms, to prevent pregnancy while taking this medicine. Seek advice from your doctor or pharmacist.
there are prograf assistance programs that the company offers. If this is not feasible than using other cheaper medications such as verapamil for example for HTN for example will alllow much lower doses of prograf to be used (it delays metabolism of the medication) and thus it comes out cheaper.
Cheilitis(Inflammation of the skin on and around the lips)is often seen in atopic dermatitis.Diagnosed by bld test like RAST.Treatment is by topical steroids or oral therapy of corticosteroids in severe cases.Topical creams like tacrolimus ointment (Protopic) and pimecrolimus cream (Elidel) are also useful.
It is very difficult to precisely confirm a diagnosis without examination and investigations and the answer is based on the medical information provided.
Treatment is by topical steroids or oral therapy of corticosteroids in severe cases. Topical creams like tacrolimus ointment (Protopic) and pimecrolimus cream (Elidel) are also useful. My sincere advice would be to consult a dermatologist.
I hope it helps. Take care and please do keep me posted in case you have any additional doubts. Kind regards.
Severe cases may need steroids, non-steroid topical anti-inflammatory creams such as tacrolimus, cryotherapy, laser treatment or UV light therapy. Consultation of a dermatologist will be the best in your case.
It is very difficult to precisely confirm a diagnosis without examination and investigations and the answer is based on the medical information provided. For exact diagnosis, you are requested to consult your doctor. I sincerely hope that helps.
Cheilitis(Inflammation of the skin on and around the lips)is often seen in atopic dermatitis.Diagnosed by blood test like RAST. Treatment is by topical steroids or oral therapy of corticosteroids in severe cases. Topical creams like tacrolimus ointment and pimecrolimus cream are also useful.
It is very difficult to precisely confirm a diagnosis without examination and investigations and the answer is based on the medical information provided.
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