i wouldnt lower the tacrolimus dose further
The specialist reviewed all of the options with us - cyclosporine, pilocarpine or tacrolimus with sirolimus. She said that very rarely has she seen any dog respond to cyclosporine after not responding to tacrolimus. She also said that because our dog doesn't have a dry, goopy nose, that pilocarpine wouldn't be a first choice. She recommended a mix of tacrolimus with sirolimus. She said sirolimus is new. I have not been able to find anything about this drug on the internet.
His cretanine is almost 1.4 or around. My question is that should he continue his TACROLIMUS tablets or should switch to some other tablets which are safe for kidneys?
Secondly , in my sorrounding there is an opinion that lowering the TACROLIMUS dose also let the liver enzymes to increase? Do you favour such opinions as my father has lowered his tacrolimus dose to keep his kidneys safe?
Sir ,will wait for your kind reply.
Thanks.
s hard to perform my job or other daily tasks when my eyelids are so inflamed. I guess steroids are the only option until they develop something better. Is Tacrolimus a promising nonsteroidal option?
The treatments of this condition are application of topical corticosteroids (betamethasone, clobatesol, flucinolone) which will reduce the inflammatory process. Topical immunomodulators like pimecrolimus and tacrolimus can be used in severe conditions.
I hope it helps. It is very difficult to precisely confirm a diagnosis without examination and investigations and the answer is based on the medical information provided. For exact diagnosis, you are requested to consult your doctor.
Hormonal contraceptives such as the pill and the patch may increase the blood level of tacrolimus. Tacrolimus may also reduce the effectiveness of these hormonal contraceptives. For this reason women who could get pregnant should ideally use a non-hormonal method of contraception, eg condoms, to prevent pregnancy while taking this medicine. Seek advice from your doctor or pharmacist.
there are prograf assistance programs that the company offers. If this is not feasible than using other cheaper medications such as verapamil for example for HTN for example will alllow much lower doses of prograf to be used (it delays metabolism of the medication) and thus it comes out cheaper.
AS I HAVE SUFFERED BREATHLESSNESS AND WALKING PROBLEMS,I HAVE BEEN TAKEN OFF TACROLIMUS AND PUT ON NEORAL-YET THERE IS NO IMPROVEMENT IN MY CONDITION.IS THERE ANY OTHER ANTI REJECTION DRUG THAT YOU WOULD RECOMMEND (I HAVE HAD A LIVER TRANSPLANT RECENTLY)? IN YOUR EXPERIENCE,CAN MY SITUATION BE IMPROVED?THANKS.
Hi, I had a mammogram Aug 27th which that the small node I have had for years has grown. Two days later I had an ultrasound that shows a hypoechoic structure deep within the chest wall and has a hyperechoic notch to it with an appeappearance of a benign lymph node but does not correlate with the position of the mammogram. Given the findings of this ultrasound and enlargemnt of the density on the mammogram biopsy is recommended. My question is would you take it out completely?
t know very much about the molecular structure. I find it a bit hard to understand, but I get pieces of it.
This one seemed more concise then the the last one I sent you.
- Dave
http://www.natap.org/2001/jun/MoleBio.
i would be extremely cautious about using it until more data is available especially since its purported effects on tacrolimus and cyclosporine metabolism are extreme. i am quite confident that there will be clinical trials coming down the road extremely soon.
My tacrolimus level is 4.2 after 4 months of liver transplant, Is it dangerous? what should i do?
Treatment is by topical steroids or oral therapy of corticosteroids in severe cases. Topical creams like tacrolimus ointment (Protopic) and pimecrolimus cream (Elidel) are also useful.
If still the symptoms do not improve then please get a clinical examination done by a dermatologist.
I hope it helps. Take care and please do keep me posted in case you have any additional doubts. Kind regards.
Within the left ovary is a complex cystic structure measuring 4.4 x 4.8 x 4.5 cm. Some sepatation is present with half of the cystic structure having either dense internal debris or a somewhat solid component. No color flow is appreciated in this abnormal half of the cystic structure. No other mass or lesion or free fluid is present wihtin the left adnexa. This is a nonspecific finding and both benign and malignat etiologies must be considered.
i had a ct scan done the said in the left adnexa there is a structure with 2 cystic areas measuring 12 and 16 mm each and has enhancing perphery i have had a hysterectomy 4 yrs ago what does thids all mean it also states i have several diverticulae in sigmoid colon but no evidence of diverticlitis what does this mean please
My doctor called and told me an irregular cystic structure was found on my left ovary along with a cyst. Could this be an ectopic pregnancy? I have had all the signs of being pregnant. This is frustrating because no one seems to be telling me anything.
My right side of my abdomen was killing me a week later I ended up in the er with severe pain and bleeding. An inner and outer US showed a 6.8cm separated cystic structure and ovarian lesion. I was told to followup with my OBGYN. Which I did. She said to wait 6-8 weeks and do a repeat US. Well I was referred to a new dr. since my old obgyn retired from that practice. The new dr. has been much more sympathetic. I saw her last friday 1/8 and she ordered more blood tests (Ca-125, Ova-1, Estradiol.
Not the right place for this question. Sorry.
I am taking Tacrolimus 3mg, Myfortic 360mg, twice a day. My Creatine is 1.25 and BUN is 29. I am also interested in your opinion.
I was initially taking Tacrolimus and then I was switched to Sirolimus. I cannot remember why my immunosuppressive was changed but Sirolimus was pretty new then and maybe my surgeon wanted to try it and see how I did. I wasn't very fond of it as I recall. It came in small packets and was an oily solution. It's been a while but I do remember that. I probably mentioned this to my surgeon and that could be the reason that he switched me back.
Another Dermatologist thought my immune system caused the reaction and prescribed Tacrolimus ointment...told me to put it on until the color came back. I did that for 3 months and didn't notice any significant change....only occasional peeling of the skin next to the head of my penis! Is there ANYTHING that will fix my skin?
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