Topical antifungals and mild steroids are the usual treatment and combination of the two can be used to treat stubborn patches. Oral antifungal drugs and immunomodulators such as tacrolimus and pimecrolimus are used in very severe cases.
I sincerely hope that helps. Take care and regards.
am Pankaj from Ahmedabad, Gujarat, I have a 7 years old kid, he is suffering from Morphea, since last 4-5 years and still i am not able to find a dermatologist who is expert in Morphea , Can anyone suggest me a Morphea Doctor near by Ahmedabad. If you have solution of my problem please mail me on ***@****.
i wouldnt lower the tacrolimus dose further
He was tested positive for ebv but afetr reduced tacrolimus dose by1 mg per day his ebv is negative. Also his biopsy reports does not indicated auto Immune hepatitis.Please let me know what is the right mathod or treatment to get his IgG and protien level normal.
Thank you for your previous respose.
The specialist reviewed all of the options with us - cyclosporine, pilocarpine or tacrolimus with sirolimus. She said that very rarely has she seen any dog respond to cyclosporine after not responding to tacrolimus. She also said that because our dog doesn't have a dry, goopy nose, that pilocarpine wouldn't be a first choice. She recommended a mix of tacrolimus with sirolimus. She said sirolimus is new. I have not been able to find anything about this drug on the internet.
VEP showed abnormality in my right eye in '06. At that time an ophth. attributed that to the tiniest beginnings of Macular Degen. Another ophth. disputed this cause. I am now being treated for MS, though it's only 'probable.'
Another puzzling thing: Had a routine eye exam this past winter, including dilation. My right pupil remained huge four hours after the left had contracted.
Could you comment on these events?
I was initially taking Tacrolimus and then I was switched to Sirolimus. I cannot remember why my immunosuppressive was changed but Sirolimus was pretty new then and maybe my surgeon wanted to try it and see how I did. I wasn't very fond of it as I recall. It came in small packets and was an oily solution. It's been a while but I do remember that. I probably mentioned this to my surgeon and that could be the reason that he switched me back.
His cretanine is almost 1.4 or around. My question is that should he continue his TACROLIMUS tablets or should switch to some other tablets which are safe for kidneys?
Secondly , in my sorrounding there is an opinion that lowering the TACROLIMUS dose also let the liver enzymes to increase? Do you favour such opinions as my father has lowered his tacrolimus dose to keep his kidneys safe?
Sir ,will wait for your kind reply.
Thanks.
s hard to perform my job or other daily tasks when my eyelids are so inflamed. I guess steroids are the only option until they develop something better. Is Tacrolimus a promising nonsteroidal option?
The treatments of this condition are application of topical corticosteroids (betamethasone, clobatesol, flucinolone) which will reduce the inflammatory process. Topical immunomodulators like pimecrolimus and tacrolimus can be used in severe conditions.
I hope it helps. It is very difficult to precisely confirm a diagnosis without examination and investigations and the answer is based on the medical information provided. For exact diagnosis, you are requested to consult your doctor.
Hormonal contraceptives such as the pill and the patch may increase the blood level of tacrolimus. Tacrolimus may also reduce the effectiveness of these hormonal contraceptives. For this reason women who could get pregnant should ideally use a non-hormonal method of contraception, eg condoms, to prevent pregnancy while taking this medicine. Seek advice from your doctor or pharmacist.
there are prograf assistance programs that the company offers. If this is not feasible than using other cheaper medications such as verapamil for example for HTN for example will alllow much lower doses of prograf to be used (it delays metabolism of the medication) and thus it comes out cheaper.
I was prescribed a fluocinonide solution for a small patch on my face. Now that I have stopped it completely, small bumps have appeared where I was putting the topical solution. The doctor now prescribed Doxycyline for 1 month and Metrogel 1%. There has been improvement, but very slowly with 2 flare ups so far. It has been two weeks since I stopped the steroid completely.
Will it ever go away? Will my skin return to the way it was before the steroid use?
AS I HAVE SUFFERED BREATHLESSNESS AND WALKING PROBLEMS,I HAVE BEEN TAKEN OFF TACROLIMUS AND PUT ON NEORAL-YET THERE IS NO IMPROVEMENT IN MY CONDITION.IS THERE ANY OTHER ANTI REJECTION DRUG THAT YOU WOULD RECOMMEND (I HAVE HAD A LIVER TRANSPLANT RECENTLY)? IN YOUR EXPERIENCE,CAN MY SITUATION BE IMPROVED?THANKS.
Oral antifungal drugs and immunomodulators such as tacrolimus and pimecrolimus are used in very severe cases. The other possibilities are of eczema, lupus erythematosus or dermatitis. Best would be to consult a dermatologist and get biopsy skin done to confirm the diagnosis.
Hope it helps. Take care and please do keep me posted if you have any additional queries. Warm regards.
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