i wouldnt lower the tacrolimus dose further
I had a blood test yesterday and results show a WBC of 2.9 and also low neutrophils of .60 (meaning I have moderate neutropenia). All other values are within range.
I had a blood test done a year ago and everything was good then (WBC of 5.6).
I don't have a fever or additional symptoms and don't think I have a virus.
I have as few questions:
1. Could this be a normal swing in my WBC, is it fairly common for healthy people to drop low and bounce back up?
2.
Are you currently on any medication like imatinib? The neutropenia can be due to your current medication. You can ask your hematologist for G-CSF injection if you have persistent neutropenia. Patients with CML are immunocompromised and can easily acquire infections. Neutropenia also puts a patient in an immunocompromised state.
For now, it is very important to prevent acquiring any infection. You should avoid crowded places and persons with ongoing infection.
Good luck.
The specialist reviewed all of the options with us - cyclosporine, pilocarpine or tacrolimus with sirolimus. She said that very rarely has she seen any dog respond to cyclosporine after not responding to tacrolimus. She also said that because our dog doesn't have a dry, goopy nose, that pilocarpine wouldn't be a first choice. She recommended a mix of tacrolimus with sirolimus. She said sirolimus is new. I have not been able to find anything about this drug on the internet.
His cretanine is almost 1.4 or around. My question is that should he continue his TACROLIMUS tablets or should switch to some other tablets which are safe for kidneys?
Secondly , in my sorrounding there is an opinion that lowering the TACROLIMUS dose also let the liver enzymes to increase? Do you favour such opinions as my father has lowered his tacrolimus dose to keep his kidneys safe?
Sir ,will wait for your kind reply.
Thanks.
re considering an interferon dose reduction?? If neutropenia, the following applies to Inf/Riba, not the PIs.
Neutropenia frequently complicates IFN-based antiviral therapy for hepatitis C [14]. The relationship between neutropenia and infectious complications in this instance is not well described.
Hello all, I'm not sure if everyone is familiar with my story but I have neutropenia and graves disease. I need to get my wisdom tooth extracted because I have avoided it long enough. When I first tried to get my wisdom pulled the dental surgeon realized that my wisdom tooth was in my nerve and that i would suffer damage if pulled. I was told to prolong it as much as I could however, I get horrible migraines (I've suffered from migraines since 13) and I need my tooth taken out.
s hard to perform my job or other daily tasks when my eyelids are so inflamed. I guess steroids are the only option until they develop something better. Is Tacrolimus a promising nonsteroidal option?
The treatments of this condition are application of topical corticosteroids (betamethasone, clobatesol, flucinolone) which will reduce the inflammatory process. Topical immunomodulators like pimecrolimus and tacrolimus can be used in severe conditions.
I hope it helps. It is very difficult to precisely confirm a diagnosis without examination and investigations and the answer is based on the medical information provided. For exact diagnosis, you are requested to consult your doctor.
Hormonal contraceptives such as the pill and the patch may increase the blood level of tacrolimus. Tacrolimus may also reduce the effectiveness of these hormonal contraceptives. For this reason women who could get pregnant should ideally use a non-hormonal method of contraception, eg condoms, to prevent pregnancy while taking this medicine. Seek advice from your doctor or pharmacist.
there are prograf assistance programs that the company offers. If this is not feasible than using other cheaper medications such as verapamil for example for HTN for example will alllow much lower doses of prograf to be used (it delays metabolism of the medication) and thus it comes out cheaper.
My 17 month old son just had 2nd blood test come back with low neutrophils and high lymphocytes. The doctor said something about neutropenia? Should i be worried or is this just sign of a virus?
Normal banded neutrophil count is 1,500 cells per microliter. A count between 500-1000, is a grade 3 risk of neutropenia, or low neutrophil count, with risk for infection.
Actually on the first day of fever and even for a day or two, initially when there is an infection, there is slight neutropenia. Then the body fights the infection and the neutrophils rise and by day five of fever most blood pictures will show increased neutrophil count.
AS I HAVE SUFFERED BREATHLESSNESS AND WALKING PROBLEMS,I HAVE BEEN TAKEN OFF TACROLIMUS AND PUT ON NEORAL-YET THERE IS NO IMPROVEMENT IN MY CONDITION.IS THERE ANY OTHER ANTI REJECTION DRUG THAT YOU WOULD RECOMMEND (I HAVE HAD A LIVER TRANSPLANT RECENTLY)? IN YOUR EXPERIENCE,CAN MY SITUATION BE IMPROVED?THANKS.
Did I develop neutropenia from the Graves disease and how do I stop the neutropenia from getting worse? Also, what are some things that I should avoid as a result of my neutropenia? In addition, my heart rate ranges from 120-140 and I feel very tired and confused. Are these feelings a result of my heart rate? Thank you in advance.
An ANC less than 500 cells/µL is defined as neutropenia and significantly increases the risk of infection. Neutropenia is the condition of a low ANC, and the most common condition where an ANC would be measured is in the setting of chemotherapy for cancer. Neutropenia increases the risk of infection.
ANC = (%neutrophils + %bands) x WBC
The unit of ANC is cells per microlitre (abbreviated µL; a microlitre is equal to one cubic millimetre) of blood."
http://en.wikipedia.
Doing some reading, Ecthyma Gangrenosum looks like the skin infections she is having and it says Febrile Neutropenia can cause this type of infection along with fevers. But febrile neutropenia is usually a side effect of cancer treatment and she has never had any treatments for anything like that. Is it possible an diabetics immune system can be compromised in a way similar to the effects of chemotherapy and she may have febrile neutropenia and not know it ?
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