Following the operation, the doctor said she had a complication called corneal melting. He treated her with steroids for more or less a month. Another doctor said she had central toxic keratopathy. After almost 5 months, her vision is still very poor and extremely blurry. At the last visit, 2 days ago, the doctor said her corneas are very irregular (irregular scarring) and she has opacity on both eyes.
i wouldnt lower the tacrolimus dose further
The specialist reviewed all of the options with us - cyclosporine, pilocarpine or tacrolimus with sirolimus. She said that very rarely has she seen any dog respond to cyclosporine after not responding to tacrolimus. She also said that because our dog doesn't have a dry, goopy nose, that pilocarpine wouldn't be a first choice. She recommended a mix of tacrolimus with sirolimus. She said sirolimus is new. I have not been able to find anything about this drug on the internet.
His cretanine is almost 1.4 or around. My question is that should he continue his TACROLIMUS tablets or should switch to some other tablets which are safe for kidneys?
Secondly , in my sorrounding there is an opinion that lowering the TACROLIMUS dose also let the liver enzymes to increase? Do you favour such opinions as my father has lowered his tacrolimus dose to keep his kidneys safe?
Sir ,will wait for your kind reply.
Thanks.
WASHINGTON – Nearly all of Greenland's massive ice sheet suddenly started melting a bit this month, a freak event that surprised scientists.
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NASA images show the extent of surface melt over Greenland's ice sheet on July 8, left, and July 12, right.
s hard to perform my job or other daily tasks when my eyelids are so inflamed. I guess steroids are the only option until they develop something better. Is Tacrolimus a promising nonsteroidal option?
The treatments of this condition are application of topical corticosteroids (betamethasone, clobatesol, flucinolone) which will reduce the inflammatory process. Topical immunomodulators like pimecrolimus and tacrolimus can be used in severe conditions.
I hope it helps. It is very difficult to precisely confirm a diagnosis without examination and investigations and the answer is based on the medical information provided. For exact diagnosis, you are requested to consult your doctor.
Hormonal contraceptives such as the pill and the patch may increase the blood level of tacrolimus. Tacrolimus may also reduce the effectiveness of these hormonal contraceptives. For this reason women who could get pregnant should ideally use a non-hormonal method of contraception, eg condoms, to prevent pregnancy while taking this medicine. Seek advice from your doctor or pharmacist.
there are prograf assistance programs that the company offers. If this is not feasible than using other cheaper medications such as verapamil for example for HTN for example will alllow much lower doses of prograf to be used (it delays metabolism of the medication) and thus it comes out cheaper.
AS I HAVE SUFFERED BREATHLESSNESS AND WALKING PROBLEMS,I HAVE BEEN TAKEN OFF TACROLIMUS AND PUT ON NEORAL-YET THERE IS NO IMPROVEMENT IN MY CONDITION.IS THERE ANY OTHER ANTI REJECTION DRUG THAT YOU WOULD RECOMMEND (I HAVE HAD A LIVER TRANSPLANT RECENTLY)? IN YOUR EXPERIENCE,CAN MY SITUATION BE IMPROVED?THANKS.
Hi Mike,
Glad to hear you are now free of Hep C. You mentioned you cleared while on Tacrolimus? Did they switch you at some point from sirolimus to tacrolimus?
You also said, "From what I have read there is no problem treating HCV with SOC while taking Sirolimus." - I don't know what SOC means??? Could you please define for me. Thx.
Also, what were your doses of IFN and RIBO while on too low a dose and then on a proper dose the last time treated.
i would be extremely cautious about using it until more data is available especially since its purported effects on tacrolimus and cyclosporine metabolism are extreme. i am quite confident that there will be clinical trials coming down the road extremely soon.
I didn't read anything of high concern to point to stds.
My tacrolimus level is 4.2 after 4 months of liver transplant, Is it dangerous? what should i do?
Um, I'm not sure if your body getting hot and "melting" your discharge is a legit. cause...lol.but, I know that your discharge does def. change when you are pregnant. I'm pretty sure it changes in different ways for everyone, bc if I compare mine to what the internet tells me, it doesn't seem the same. I wear a panty liner everyday though, to keep myself fresh and clear of it.
You should also try different lotions cuz with my first son I couldn't use coco butter nd with this on I can only use jergens
is surely an answer, but at this point my face is getting leathery and needs repair. Any ideas? What is causing this? How to repair the damage? I know my sweat is rather acidic - eats the letters off of a computer keyboard.
Treatment is by topical steroids or oral therapy of corticosteroids in severe cases. Topical creams like tacrolimus ointment (Protopic) and pimecrolimus cream (Elidel) are also useful.
If still the symptoms do not improve then please get a clinical examination done by a dermatologist.
I hope it helps. Take care and please do keep me posted in case you have any additional doubts. Kind regards.
Thanks you guys!! I was a littles worried!!
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