since then, his corneas have been very dry and he takes three eye meds a day - tacrolimus for tear production, flurbiprofen (anti-inflammatory), and Ocusol A.
Recently, I noticed that when he swallows(not while eating but during the normal course of things like we humans do), there is sometimes a dry "clicking" sound and that once in a while an indrawn breath will sound like a sob (for lack of a better description) but he has not been in any apparent distress.
i wouldnt lower the tacrolimus dose further
The specialist reviewed all of the options with us - cyclosporine, pilocarpine or tacrolimus with sirolimus. She said that very rarely has she seen any dog respond to cyclosporine after not responding to tacrolimus. She also said that because our dog doesn't have a dry, goopy nose, that pilocarpine wouldn't be a first choice. She recommended a mix of tacrolimus with sirolimus. She said sirolimus is new. I have not been able to find anything about this drug on the internet.
His cretanine is almost 1.4 or around. My question is that should he continue his TACROLIMUS tablets or should switch to some other tablets which are safe for kidneys?
Secondly , in my sorrounding there is an opinion that lowering the TACROLIMUS dose also let the liver enzymes to increase? Do you favour such opinions as my father has lowered his tacrolimus dose to keep his kidneys safe?
Sir ,will wait for your kind reply.
Thanks.
s hard to perform my job or other daily tasks when my eyelids are so inflamed. I guess steroids are the only option until they develop something better. Is Tacrolimus a promising nonsteroidal option?
The treatments of this condition are application of topical corticosteroids (betamethasone, clobatesol, flucinolone) which will reduce the inflammatory process. Topical immunomodulators like pimecrolimus and tacrolimus can be used in severe conditions.
I hope it helps. It is very difficult to precisely confirm a diagnosis without examination and investigations and the answer is based on the medical information provided. For exact diagnosis, you are requested to consult your doctor.
Hormonal contraceptives such as the pill and the patch may increase the blood level of tacrolimus. Tacrolimus may also reduce the effectiveness of these hormonal contraceptives. For this reason women who could get pregnant should ideally use a non-hormonal method of contraception, eg condoms, to prevent pregnancy while taking this medicine. Seek advice from your doctor or pharmacist.
there are prograf assistance programs that the company offers. If this is not feasible than using other cheaper medications such as verapamil for example for HTN for example will alllow much lower doses of prograf to be used (it delays metabolism of the medication) and thus it comes out cheaper.
AS I HAVE SUFFERED BREATHLESSNESS AND WALKING PROBLEMS,I HAVE BEEN TAKEN OFF TACROLIMUS AND PUT ON NEORAL-YET THERE IS NO IMPROVEMENT IN MY CONDITION.IS THERE ANY OTHER ANTI REJECTION DRUG THAT YOU WOULD RECOMMEND (I HAVE HAD A LIVER TRANSPLANT RECENTLY)? IN YOUR EXPERIENCE,CAN MY SITUATION BE IMPROVED?THANKS.
i would be extremely cautious about using it until more data is available especially since its purported effects on tacrolimus and cyclosporine metabolism are extreme. i am quite confident that there will be clinical trials coming down the road extremely soon.
My tacrolimus level is 4.2 after 4 months of liver transplant, Is it dangerous? what should i do?
Treatment is by topical steroids or oral therapy of corticosteroids in severe cases. Topical creams like tacrolimus ointment (Protopic) and pimecrolimus cream (Elidel) are also useful.
If still the symptoms do not improve then please get a clinical examination done by a dermatologist.
I hope it helps. Take care and please do keep me posted in case you have any additional doubts. Kind regards.
Is thislymphoma of the skin? When he says lymphoma is he talking about lymphoma in general or just lymphoma of the skin? He also mentioned that he would check my nodes in my neck as well. If it does turn out to be lymphoma of the skin in future, does this mean it is t cell? I'm just worried right now about 2 issues.
1) when he says lymphoma is he just talking about the skin?
Hi,
I'm an 18 year old girl and I found a very hard, painless lump under my right ear. It's about the size of a quarter and it's in my neck....like I had to find it. I have an appointment in two weeks to see my doctor and discuss what's going on. I haven't had any symptoms besides stomach pains, and these awful headaches on the left side of my head. I had a CBC done two weeks ago and both counts were very good.
Can lymphoma be painful. I have had painful lymph nodes for months and thought I had hiv. But tested negative outside the window. I've also tested for all the infectious causes I can think of. Now I will need a biopsy. Can anyone answer this for me.
My major worry is Lymphoma obviously. I am 23 years old do not smoke, barely drink anymore. Another bit of information is I need to get my wisdom teeth pulled out later this month not sure if this is the root of all the problems (dentist and ENT said no). What should I do next? CT scan? Endoscopy? (Had severe heartburn first time in my life with stomach burning dr put me famotidine for 2 weeks went away, sometimes still get minor burning sensation rarely) Biopsy?
Recommended
