i wouldnt lower the tacrolimus dose further
The specialist reviewed all of the options with us - cyclosporine, pilocarpine or tacrolimus with sirolimus. She said that very rarely has she seen any dog respond to cyclosporine after not responding to tacrolimus. She also said that because our dog doesn't have a dry, goopy nose, that pilocarpine wouldn't be a first choice. She recommended a mix of tacrolimus with sirolimus. She said sirolimus is new. I have not been able to find anything about this drug on the internet.
His cretanine is almost 1.4 or around. My question is that should he continue his TACROLIMUS tablets or should switch to some other tablets which are safe for kidneys?
Secondly , in my sorrounding there is an opinion that lowering the TACROLIMUS dose also let the liver enzymes to increase? Do you favour such opinions as my father has lowered his tacrolimus dose to keep his kidneys safe?
Sir ,will wait for your kind reply.
Thanks.
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The doc states there
ECLIA (electrochemiluminescence immunoassay) is a type of immunoassay.An immunoassay is a biochemical test that measures the concentration of a substance, using the reaction of an antibody or antibodies to its antigen.Depending on what is linked to either the antibody or the antigen, there are several types of immunoassay: enzyme immunoassay (EIA), radioimmunoassay (RIA), magnetic labels (MIA), Enzyme-Linked Immunosorbent Assay (ELISA).
s hard to perform my job or other daily tasks when my eyelids are so inflamed. I guess steroids are the only option until they develop something better. Is Tacrolimus a promising nonsteroidal option?
The treatments of this condition are application of topical corticosteroids (betamethasone, clobatesol, flucinolone) which will reduce the inflammatory process. Topical immunomodulators like pimecrolimus and tacrolimus can be used in severe conditions.
I hope it helps. It is very difficult to precisely confirm a diagnosis without examination and investigations and the answer is based on the medical information provided. For exact diagnosis, you are requested to consult your doctor.
Hormonal contraceptives such as the pill and the patch may increase the blood level of tacrolimus. Tacrolimus may also reduce the effectiveness of these hormonal contraceptives. For this reason women who could get pregnant should ideally use a non-hormonal method of contraception, eg condoms, to prevent pregnancy while taking this medicine. Seek advice from your doctor or pharmacist.
there are prograf assistance programs that the company offers. If this is not feasible than using other cheaper medications such as verapamil for example for HTN for example will alllow much lower doses of prograf to be used (it delays metabolism of the medication) and thus it comes out cheaper.
2 Antibody (Estimations are Carried Out By Automated Chemiluminescent Microparticle Immunoassay system) at 52 days. Both the result were negative. After 2 weeks of the exposure I felt sore throat & gum swollen problems. Both the problems are continuing current now. Its my 10 weeks and now I can see there are some red pimples at my armpit & hand. I also felt a pump at my right armpit. Now its gone.
AS I HAVE SUFFERED BREATHLESSNESS AND WALKING PROBLEMS,I HAVE BEEN TAKEN OFF TACROLIMUS AND PUT ON NEORAL-YET THERE IS NO IMPROVEMENT IN MY CONDITION.IS THERE ANY OTHER ANTI REJECTION DRUG THAT YOU WOULD RECOMMEND (I HAVE HAD A LIVER TRANSPLANT RECENTLY)? IN YOUR EXPERIENCE,CAN MY SITUATION BE IMPROVED?THANKS.
After 12 weeks on last exposer i took HIV and HSV test ,I got negative for HIV with CMIA test
but for HSV I got test result HERPES SIMPLEX VIRUS (HSV) 1 + 2 IgM, SERUM (Enzyme Immunoassay) - 0.50 HERPES SIMPLEX VIRUS (HSV) 1 + 2 IgG, SERUM (Enzyme Immunoassay) = 26.90 This means i have Herpes ?
the reference values are The reference value is 1.10 Reactive.
It will be helpfull for me if some one tell me do i need to go for which test if i have HSV to check for HSV1 or HSV 2?
It should say clearly negative at this time since a 4 wk antibody test is not conclusive
How soon after exposure to HCV can anti-HCV be detected?
HCV infection can be detected by anti-HCV screening tests (enzyme immunoassay) 4–10 weeks after infection. Anti-HCV can be detected in >97% of persons by 6 months after exposure
http://www.cdc.gov/hepatitis/HCV/HCVfaq.
In part it depends on the type of test that is done. Some drug tests are more sensitive (and accurate) than others. Initial (immunoassay) and confirmatory (gas chromatography-mass spectrometry [GC-MS]) testing are the methods most commonly utilized to test for drugs. Using a combination of both tests allows a high level of sensitivity and specificity, meaning there is an extremely low chance for false positives or false negatives.
There is a company that has an FDA approval for Microparticle Chemiluminometric Immunoassay for HIV1/O/HIV2. It was approved in May of 2006.
i would be extremely cautious about using it until more data is available especially since its purported effects on tacrolimus and cyclosporine metabolism are extreme. i am quite confident that there will be clinical trials coming down the road extremely soon.
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