The hives appeared a few weeks after
Solu-
Medrol treatment; my dr did not think it was associated with the drug. I had
hives on my forhead, hips, inner thighs, shins and toes, almost entirely symmetrical, like a mirror image on both sides of my body. Treated with oral and topical Benadryl, went away after several days.
This was my only major MS attack thus far, so it will be interesting to see whether hives will accompany the next one.