“If you are unaware that a patient is on simvastatin and you give either boceprevir or telaprevir, the simvastatin level in the blood can go high and patients can develop muscle breakdown,” said Dr. Jensen.
http://www.idse.net//ViewArticle.aspx?
UID=
The above study has been in the news lately and compares both dietary and lifestyle changes with with Red Yeast Extract (RYR) against a more pharmaceutical statin-only approach to improve cholesterol, triglicerides, etc.
While the study doesn't specfically mention HCV, studies do suggest that the aforementioned approach can be helpful with Non-Alcoholic Fatty Liver Disease (NAFLD), a condition that can accelerate fibrosis.
http://www.medscape.
also start hepatitistechnologies products as soon as possible if you can afford
lower your cholesterol to total chol<150mg/dl, ldl50mg/dl, you can use both simvastatin or red yeast rice with standardized monacolin content about 6mg.
5 mg @ hs PRN and oxycodone 5 mg 2 tabs bid for chronic pain. The red yeast rice will be for reducing my elevated Cholesterol as noted: (VLDL=18; TRIGLYCERIDES=92; LDL=155; HDL=59; TOTAL CHOLESTEROL=232). I was initially prescribed Crestor 5 mg by my PCP but due to some severe side affects I stopped taking it.
forgot about cholesterol but i am using red yeast rice for now, not simvastatin, which is the only one with proven activity on hbv:
tot chol 164
ldl 92
hdl 61
trgl 57
good numbers close to ideal numbers reported from studies as:
tot chol<150
ldl50
Clinicians should review supplement contents for the presence of red yeast rice, and patients taking red yeast rice should be monitored for changes in liver function and counseled about the possibility of myalgias and drug interactions. Finally, patients taking red yeast rice should be warned about potential risks and precautions pertaining to all nonregulated supplements.
x/full
very interesting study which confirms why simvastatin, lowering cholesterol drug and actos (diabetes 2 drug), have anti hbv activity lowering hbvdna, cancer risk, all this without problems of resistance and acting on all hbv mutants
conclusions:
The discovery of the mechanisms by which HBV is controlled by the hepatic metabolic milieu may broaden our understanding of the unique regulation of HBV expression and may also explain the mechanisms by which HBV induces liver pathologies.
Dear Professionals:
I am faint and dizzy on a "daily" basis. I've been to the ER twice and the doctor's office five times. I'm on Meclizine daily (I can take up to 150 mg daily, but I only take 25 to 50 mg daily) and 81 mg aspirin. I've had two EKG's, one Echo test, my MRI is on Monday, Jan 9th and a Bilateral Carotid Ultrasound, Jan 26th.
I am suppose to start Lipitor.
Btw My mother is 94 and takes supplements to help herself. She takes: Cod Liver oil, Magnesium, Milk Thistle, and Flaxseed oil. Her cholesterol levels are good and the only medication she takes is one Glipizide a day for her Diabetes which is almost reversed. She uses only Olive Oil to cook with and loves fried foods! This little old lady runs circles around me and I am 69! I sincerely hope your mother starts feeling better soon. - you might want to wean her off the statins though.
P.S.
I eat avocados to lower mine. Mine was so high a few years back that the doctor had prescribed pills...which he said may or may not work as mine is inherited ( and yes, there is such a thing ). I ended up getting pregnant ( so refused the pills just in case ) and started craving avocados. Went back a few times for blood tests ( as is typical when prego ) and my LDL had dropped...by a lot!
The doctor asked me how I did it...asked what had changed.
red yeast rise (which contains naturally lovastatin, simvastatin and some other statins), simvastatin or other more powerful statins?
is simvastatin the most potent since used already with interferon and studied in vitro with antivirals (most potent sim+etv 300:1)
aslo what is the meaning of 300:1?150mg sim+0.5mg etv?
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