CARLSBAD, Calif., Jan. 13, 2016 /PRNewswire/ -- Ionis Pharmaceuticals, Inc. (NASDAQ: IONS) today announced that GSK has initiated a Phase 1 study of IONIS-HBV-LRx. Ionis earned a $1.5 million milestone payment from GSK related to the initiation of this study. IONIS-HBV-LRx, which was previously referred to as ISIS-GSK6-LRx, is a drug Ionis is developing with GSK for the treatment of patients with hepatitis B virus (HBV).
Two trial using GSK drugs? Which hepatits C drugs does GSK make? I don't recall reading that they play in hcv. I guess I've missed something.
our father who is 78 is starting to hallucinate he was hospitalized about a month ago for pneumonia.he was also taking requip for his restless legs,the doc. took him off of requip because of side affects 4 days ago. we dont know if that could be the cause of his condition or not,he also had a cat scan of the brain, it was normal.he sees people that are not there, he realizes later that it is not real. he is getting depressed and scared,we dont know what to do anymore.
This result met with little concern. After diagnosis RLS 10/07 started Requip. Worked like magic from first .Actual RLS symptoms abated, bad wakings CEASED. Was at 2 mg nightly. End 1/08 small weight gain, minor edema. Short of breath. Suddenly symptoms increased.Gained more than 25 lbs in 10 weeks.Feet/ ankles/ fingers/abdomen terribly swollen. All sorts of tests including kidney,liver,congestive heart failure. No answers. Back to neuro.
Besides Mirapex, the other medications that are approved to treat Restless Legs Syndrome are Neurontin, Requip and Neupro. I recommend speaking to your doctor about these medications to see if one may be appropriate for you.
I've got severe RLS 24/7 and have been taking Requip for the past several years, Mirapex before that. It's gotten worse lately so the doctor had me go cold turkey 5 days ago. He gave me Klonopin to take at night, but it doesn't do anything other than make me even more tired. I managed to get 6 hours sleep on day 4, but that's it for the whole week. The doctor says that I can't go back on the dopamines (Requip) since they have started augmentation (making the RLS worse).
It's possible that you have a real medical issue with RLS and if that's the case Requip works great and it's not addictive!
On the other hand if it does have something to do with w/d's then I would suggest eating bananas as they really do help.
If the bananas don't work after a few days then I would go to your doctor and tell him what's going on with your legs and he will probably give you the Requip. I'm currently taking it and with no side effects at all.
Today was my big 10! I feel great. I do still have my rls but I take Requip at night and it makes me sleep like a baby! Ready to watch some titans football tonight and leave for Florida vacation in two weeks!
Has anybody had success with requip? If so, what dosage of requip worked for you? They have .25, .5, 1.0, and 2.0.
Do you take the medicine at night only or during the day too?
I really appreciate your help. I made it 14 days off hydros last year, but the RLS was agonizing and I gave in. I want to do EVERYTHING I can to help ease this upcoming hell.
I started taking Requip last year for RLS. I just happen to mention to my doctor that I had leg pain during the night. She had given me a trial pack but left it at home when I went to my daughters for the weekend. I had only been taking it a few days and when I didn't have it to take I thought i was dying. It is like I am addited to this drug. I can't come off of it. I have started having shooting pains in my legs and find that I am having to take it more often.
Also if you contact your GSK valtrex rep, they can give you some terrific packets for the medical providers in your clinic as well as wonderful packets to hand out to patients who are newly diagnosed too.
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