My current sleep doctor feels that Sinemet, a dopamine replacement, should be reserved for use after dopamine agonists such as Requip and Mirapex are no longer useful.
I can give you a few hints on optimizing the effectiveness of your Sinemet rather than keep raising dose: No protein to eat unless long enough before dose for the food to have already passed thru the small intestine. Small amout of starchy food food can help when taking med, but no large amounts of food before taking the med.
Duke University Medical Center recommended the target range of 3.0 to 3.5 for the St Jude Medical leaflet valve. I have been on it since 1993. The instability has been only the last three years or so. Here's a link to a presentation that suggests vitamin K and the logic for doing so; http://www.dcpa.us/slides09/sun05.trujillo.vitk.
It sounds like you have been diagnosed with RLS and requip worked for you well until it was determined to be causing side effects, and you were switched to Sinemet. One known side effect of Requip is swelling in the legs; it sounds like you had an extensive evaluation for all the symptoms you began experiencing after January 2008.
Sinemet works well for RLS symptoms, but has a higher risk of eventually causing what is called augmentation, or the occurrence of symptoms earlier in the day.
My father in law is an alcoholic who has Atrial Fibrillation and is on coumadin. His cardiologist will not perform a cardioversion for him until his INR is within an acceptable level but it never is! The coumadin nurses frequently tell him his levels are too high and tell him to not take any coumadin for days at a time then the cardiologist tells him his INR is top low and they post pone the cardioversion.
It is supposed to be worse after long night without sinemet (requip 0.125 is given every other night and no significant distinguish between with and without it) Sinemet suppose to make motion better and it DID make her better before. Or Dyskinesia completely overridden others (but the Dyskinesia is happened in the jaw/tongue and I don't see any tremor in legs/feet)
I tried to find a logic explanation, but no luck! Can this imply sinemet is no good for her anymore?
We usually admit the patients 3 days prior to the surgery when we withhold coumadin and start heparin once the INR is less than 2.0. After surgery we usually start the heparin 12 hours after the surgery and coumadin shortly thereafter. The patient usually don't leave the hospital until their INR above 2.0. These are not hard and fast rules, and some physicians are more careful than others.
The body has a hard time clotting the blood due to aging. Also, Coumadin is hard on the arteries and with her age her arteries may be weak or thin. Coumadin is a very strong blood thinner and has some very serious side effects such as stomach cancer. It also can cause osteoporosis. Before her doctor starts her on any blood thinner, make sure that she has blood drawn and it is proven that her blood is thick enough to require this. You also may want to seek a second opinion.
Dear Kat,
I do know that taking Requip itself can cause hallucinations. But he's been taken off it. Now, stopping Requip can cause confusion. So, I don't know what to make of it. I do recall when I had pneumonia, I was out of my mind, and I have never taken Requip. I suppose it's possible he's having a combination of fever hallucinations, left-over Requip hallucinations, and withdrawal confusion. Any way you look at it, he's having a very hard time.
t do an ablation. I am now wearing and event monitor for 30 days. I have a feeling he wants me to go on coumadin. I don't want to do that because I am very active and I am petrified of bleeding out. when I went to my accupuncturist she said she believes it is happening because of the sympathetic nerve due to the stress I have been under. I also read where taking 40mg of vitaminB6 helps the arrhythmia. What are your thoughts on my situation.
She has really bad swelling in her legs, from the knees down, including her ankles and feet. Since her Coumadin dosage was doubled due to low INR levels about 6 months ago, the swelling has gotten worse. I understand that correlation is not causation, but is this common?
Also, do they ever decrease one's dosage of blood thinners, or is it always the other way around.
I have 2 artificial heart valves and am taking coumadin (target INR 2.5 - 3.5). I am living overseas and have very limited access to fresh/frozen fish. To help regulate my INR, I do have a portable tester that works well. I'm wondering if the blood thinning effects of fish oil (if any) will be measured by my INR testing machine. In other words, will the total blood thinning effects of both coumadin and the fish oil suppliments be measured by the INR?
I took requip for about five years - worked, no problem. Then about 4 months ago, I started getting, out of the blue and for no obvious reason, anorexia, nausea, and finally light stomach ache. After a lot of investigative stuff, including an EGD, my gastroenterologist discovered the cause: I had become allergic to requip. Just a note of caution.
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