Medication can be totally unpredictable. For example, from 2007 to 2010 I was on blood pressure medication
Ramipril with absolutely no problems. In May 2011 I was asked to go back on them because my BP was borderline, but for reasons unknown, they gave me lots of chest pains. At first nobody knew what it was, but after three days I stopped the Ramipril and the pains stopped. So even the same medication we have taken at some point in the past can have different results.