raloxifene pi

Lymphnodes clear and had five weeks of radiation treatment. Tried Tomxifene but made me ill. Dr, recommended Raloxifene. does Raloxifene prevent the recurrance of my type of breast cancer? Marian This discussion is related to <a href='/posts/show/261381'>Aromatase vs. Raloxifene</a>.

I am supposed to start Raloxifene. This may cause hot flashes. If severe enough, dr will rx Effexor to treat flashes. I have been reading such negative information about the side effects of Effexor, and even worse, the are withdrawal symptoms if you have to get off of it. Is there anyone reading this that actually had to take effexor along with Raloxifene? If so, could you tell me please if you had a good, or bad experience? Thank you for any input.

The medications currently FDA approved as chemoprevention for breast cancer are tamoxifen and raloxifene. Decisions to use a medication as chemoprevention would be made based on weighing the risks and benefits to the individual patient.

less evidence was found for raloxifene. the USPSTF found good evidence that both tamoxifen and raloxifene increase the risk of thromboembolitic events (stroke, DVT, PE). they found that tamoxifen increases the risk of endometrial CA. the USPSTF recommends screening for colon CA starting at age 50 in men and women. earlier screening recommendations depend on the patient, family history and medical conditions (ie they are different for conditions such as ulcerative colitis, etc).

Aside from radiation, you can ask your doctor about other breast cancer risk reduction strategies such as that of hormonal treatment with tamoxifen or raloxifene. Other breast conditions that may increase the risk of invasive cancer would include DCIS (ductal carcinoma in situ). Regards.

Use of Raloxifene is intended to decrease the risk of osteoporosis and to decrease the risk of invasise breast cancer or to prevent invasive breast cancer from retuning in women who have had invasive BC. If you have questions or concerns about using it, it would be best to discuss them with the physician who prescribed it. Best wishes...

I am not sure which medication your mother is taking, but Evista (raloxifene) can cause muscle cramps of the legs. Please have your mother make an appointment with her physician.

I have been told by Oncologist that have 5 times risk factor for breast cancer. Am on raloxifene. Last nite I noticed some dimpling on the biopsied breast abt 1" from incision scar. Just had a manual exam by the Oncologist and don't want to seem like a hypochondriac, but should I see him again. He felt nothing during manual exam, but the lump that was removed was not palpable either and only detected by mammo.

Other forms of treatment post-operatively would include additional radiation therapy, or hormonal treatment with Tamoxifen or Raloxifene. All of these additional treatments are aimed to lessen the chance of recurrence as well as prevent the future development of frankly invasive cancers. Regards.

In addition, women over the age of 35 with LCIS who are at treated at the Cancer Center have access to a similar drug, Raloxifene, that may also reduce the risk of developing breast cancer. Cancer Center physicians are participating in a clinical trial called STAR, where the effectiveness of Raloxifene is being compared to that of Tamoxifen for the prevention of breast cancer in high risk women.

If a person is treating with the PI drugs and fails to get SVR.does it mean that you cant use the PI`s ever again.this is what im gathering from what ive been reading ...looks like its do or you know what....man...sometimes i wonder how i deal with all thie stuff.

Maybe one day they will use the PI as maintenance for the ones who dont respond to SOC and PI drugs.Ive heard of aids people liiving a lot longer now because of the PI`s too.Some are with aids for 25 years and still doing ok. "An apple a day keeps the doctor away, But if the doctor is cute forget the fruit.

Osteoporosis medications like Raloxifene (Evista), alendronate (Fosomax), risendronate (Actonel) and ibandronate (Boniva) all can cause flu like symptoms in individuals that are taking them. I am not sure what medications you are on, but this could be your problem.

The hormone therapy has so many side affects. The drugs suggested for me are Arimidex or Raloxifene. Is there anyone that does not take hormone therapy and is still doing well with no recurrance?

I suggest that you discuss with your oncologist regarding additional treatments like tamoxifen or raloxifene. These two drugs are proven to further decrease the chance of the cancer recurring on the same or the other breast and I believe would be of great benefit to your mother. However, these drugs have side effects that I believe are manageable and should be discussed well with the oncologist. Regards.

I believe that you are a candidate for risk lowering strategies such as taking hormonal agents (raloxifene or tamoxifen), or surgery (mastectomy). All of these should be discussed with an oncologist or surgeon. Regards.

I knew it would work! They want me to extend out to 52 weeks, though. I already decided to take myself off the study after the 12 weeks of the study drugs. My job is on the line, I start Grad school in the fall, and I've had just about every side effect there is from the SOC drugs. It would have been nice to get the PI in the beginning, but it didn't happen. I was still detectable at week 16 on those 2, and they are the ones causing me to be so sick! OK, done with my rant.

He was told to do laser PI to prevent the glucoma first. Just wonder if the laser PI is needed and is it will worsen the catarct situation since he plans to have the cataract removed at least 6-9 months later.

I was thinking about this recently. If somebody try's a PI, and fails / builds resistance to that PI, then re-infects somebody else in the general population with Hep C - won't the disease gain resistance to that PI? The new mutation could spread, and become the standard for Hep C (given the new resistance, will make it live longer). Are PI's a short term fix, that the virus will eventaully become resistant to?

Thank you for your comments... it's much appreciated! God bless you, too!

There are some medications that are used to treat breast cancer that can be tried, though they would be used off label. These include tamoxifen (Soltamox) and raloxifene (Evista), here in the U.S. Another is Danazol. I don't know if they would be available in your country or not. Some of these drugs are quite potent and may have unwanted side effects. Be sure to discuss all of that with your doctor prior to taking them. The other option is the surgery.

Good article on PI drug treatment regimens by IAmTheWalrus http://www.medhelp.

TBG excess production can be hereditary, which is X-linked dominant transmission, or it can be secondary to excess estrogens, as in pregnancy, use of oral contraceptives, hormone replacement, and medications like raloxifene or tamoxifen [4, 5]. The more highly sialylated TBG is cleared more slowly from plasma than the more positively charged TBG, because sialylation inhibits the hepatic uptake of glycoproteins.

If your talking about the third drug being the PI as info they have not been approved for genotype 2, 3 and 4. If you are genotype 1 some insurance companies will initially deny the PI because it is so costly. Your doctor will have to start an appeal process with the insurance company which may take a little time but usually in the end the PI is approved.

I vote for boceprevir since it has a 4 week lead-in before starting the PI. If you clear in the first 4 weeks of TX, you are responsive to interferon and do not need to add a PI with all its extra side effects and risks.

Common Questions and Answers about Raloxifene pi

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