Norvasc onset of action
Common Questions and Answers about Norvasc onset of action
norvasc
I just got out of the hospital after an episode of severe chest pains, dizziness, and pain down my arms and into my neck. I had a series of tests. several ekg's x-rays, an echo, a treadmill stress test, and an angio. the stress test was abnormal. the ekgs are showing PVC's, and the angio was normal. the cardiologist is thinking that it is the endothelials that are causing the pain. they put me o n 5 mg of norvasc, and zocor because they found my ldl's were 180.
I have consulted several MDs, who are good friends of mine, and got different views on the possibilities of adding a Calcium Channel Blocker, e.g. Norvasc, to the Beta Blocker (Tenormin) that I'm taking right now. One suggested adding 2.5 mg Norvasc to the 100 mg Tenormin; another thought it would be a good idea to reduce the tenormin to 50 mg and take 5 mg of Norvasc; and the third, suggested to gradually replace the tenormin by 5 mg Norvasc, and to be increased if needed, to 10 mg.
It was decided to add Norvasc 5mg INSTEAD of Nifedipine, since Norvasc was used/tolerated well in the past. Began taking Norvasc 5mg along with Lorsartan 100mg and Atenolol 25mg (all 1x daily) approximately 3 days ago, and the blood pressure is still running extremely high. This morning reading was 186/85 and tonight 176/110!!! Worried that this can be dangerous. What should be done? How long until the BP goes to a "normal" range? Does the doctor need to increase the Norvasc dosage?
I'm a 64 yrs. old woman who used to take Diovan 320 mg. & Toprol 50 mg. for my B.P. My B.P. readings was okay but my Doctor discontinued the Toprol because my heart rate usually on the 40's. I am currently taking Norvasc 5mg. with the Diovan 320 mg. So far, my B.P. readings is very good, 110/70. But eversince I started the Norvasc, my left leg is swelling and it is becoming worst. I'd like to ask my Doctor to discontinue the Norvasc.
They may claim to do the same things, however the standards in manufacturing the medications are not the same from laboratory to laboratory and there is no way to know if you are getting exactly the same dose of medication in the Lotrel as you did in the Norvasc since they are manufactured by two different manufacturers.
The very same issue is seen with Synthroid and Levothyroxine. In fact, my sister was told by an endocrinologist at Mayo, "Never use Levothryoxine.
m interested in hearing from anybody who has had similar symptoms, or a similar course of action before getting a diagnosis. I have never really heard of tinnitis or vertigo being symptoms of MS, and those are the main reasons I even started pursuing medical help to begin with. The doctors have ruled out some explanations (like the acoustic neuroma), but there are still other possibilities on the table (Meniere's disease, or even high blood pressure for example).
I suffered with angina for several years. Recently, I had angina that would wake me out of a dead sleep. It was diagnosed as vasospasms. I was put on Norvasc a month ago. I haven't has any angina, stable or variant. Norvasc works great for me. I have some swelling and slight dizziness with the Novasc, but the benefits far out weigh the side effects.
It kind of sounds like a form of Action tremors, but I have to agree with mkh9.
Individuals with coronary spastic angina have abnormal responses to constrictive and/or dilative stimuli as a rsult of a localized or diffuse disorder of the coronary artery complex..
I assume the diagnosis of hyperreactive responses not only to the constrictor effects of acetylcholine, but also the dilator effects of nitroglycerin were detected diffusely in the epicardial coronary arteries of patients with coronary spastic angina.
I've been on 50mg of Atenolol for years, and it's done the job well enough. In the past six-eight months or so, I've noticed that my blood pressure has been having a hard time getting under 140/80. It gets under, but it doesn't stay there for very long. When I told my cardiologist, he said we should try to up my Atenolol. I declined to do so because Atenolol gives me brachycardia to the point where my pulse can be as low as the high 40s when I'm sleeping.
Agree if it were thyroid I would probably have other symptoms
One of the things that really scared me is the comment from the ED doc he is admitting me because of changes in the anterior leads. I did not see any of my hospital EKGs, and am not an expert by any means, just the basics, but the "widow maker" is an anterior MI.
I do have a copy of the EKG from my PCPs office with flipped t waves in V2, V3, V4.
Interesting Link - I too have the onset of high BP - partially drinking related I'm sure. I've been taking Norvasc (generic) as a cacium inhibitor. I keyed this drug in to the website and found many bad reviews. I don't know what to say - I don't think this website would give a good review on ANY drug. I know it is an unbiased site, but I figure most of the people who are on that site are people who are negative about the drug already.
The onset of action ranges from 45 minutes - 1 ½ hours, and the duration of action is six hours. Diazepam carries a bi-phasic half-life of 20-50 hours (for Diazepam), and 30-200 hours (for Desmethyldiazepam). Valium is indicated for the long-term management of generalized anxiety and tension-anxiety. Tolerance will not develop to the anxiolytic property of Diazepam, although tolerance will develop to the sedative/hypnotic property.
A partial µ-opioid receptor agonist, its mixed agonist/antagonist activity affords it a lower risk of dependence and abuse than full µ agonists like morphine. Meptazinol exhibits not only a short onset of action, but also a shorter duration of action relative to other opioids such as morphine, pentazocine, or buprenorphine.
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