Its toxicity depends on the route of administration, duration, exposure and dosage. The route of administration is the most important determinant of toxicity. I hope this helps.
Female age 50 ... I was being treated for pneumonia with 10 days of levaquin and lodrain 24 D. On the fifth day I started having moderate and continual pain between my sholder blades in the upper back and heartburn (no heartburn for 25 years previously) and extreme fatigue. I thought it was the pneumonia and didn't go to the doctor for five days. My blood test then showed troponin was high, doctor said I may have had a heart attack. Doctor wanted a stress test ... which showed normal.
If you miss a dose of Nitroglycerin Patch, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once. When used for long periods of time without a break, some people develop a physical need to continue taking Nitroglycerin Patch. This is known as physical DEPENDENCE. Do not suddenly stop taking Nitroglycerin Patch without your doctor's approval.
Would this route of administration work similar to faster acting benzodiazepines such as Xanax or Ativan, or does it depend solely on having a steady amount of Klonopin in your bloodstream already?
I'm confused; why would a doctor prescribe Klonopin for anxiety attacks (i.e., take it as needed)?
Well, Viagra is not safe at all in the presence of nitroglycerin tablets and in fact, we know that if anyone takes Viagra with nitroglycerin tablets, that the blood pressure can be lowered precipitously and can be lowered to such levels as can be extraordinarily dangerous to you. [ABC News report from May 2008 - Internet]
As we know, not everyone experiences negative side effects from every medication.
Steady-state plasma concentrations of nitroglycerin are reached by about two hours after application of a patch and are maintained for the duration of wearing the system (observations have been limited to 24 hours). Upon removal of the patch, the plasma concentration declines with a half-life of about an hour. If there were to be side effects, it seems it would be within hours.
I only take isosorbide prior to a workout, and nitro when engaged in an activity that brings on angina. I understand your doctors are suggesting taking isosorbide daily as aschemia does not always produce angina even though the heart cells are not getting sufficient blood supply. This can lead to a silent heart attack so the medication is recommended continuously whether there is angina or not and older people in general are likely to have a silent heart attack.
While chest pain that gets better with nitroglycerin can be suggestive of agina, there are several other types of chest pain, such esophageal spasm, that can get better after nitroglycerin. Exercise tests and stress echocardiograms are screening test for coronary artery disease. If these screening tests are abnormal, the next step is most likely a cardiac catheterization and angiogram in order to look definitively at your coronary arteries.
I assume the diagnosis of hyperreactive responses not only to the constrictor effects of acetylcholine, but also the dilator effects of nitroglycerin were detected diffusely in the epicardial coronary arteries of patients with coronary spastic angina.
The goal of treatment is to control chest pain and to prevent heart attack. The pain is relieved by a medicine called nitroglycerin (dilates coronary vessels). You have been prescribed norvasc and that should relieve any chest pains.
The only sympton he has had with the placing of the stents was Chest Pressure, no other symptoms. The same with his recent heart catherization was chest pressure. In the ER he was given 2 nitroglycerin, 5 minutes apart, the chest pressure went away after the 2nd nitroglycerin.
Does any good specialist in cardiology think that my husband should have the open heart surgery for bypasses considering the risks regarding his age, his diabetes?
There is no benefit to taking this sublingually that I know of. Generally the reason you take anything that way is to get it into your system as quickly as possible or because saliva is beneficial to absorption. With 5-HTP, it takes some time for your system to react to it assuming your body finds it necessary to have more coming in -- if it doesn't, it just evacuates it. The same thing is true when you take medication targeted at serotonin, though they work quit differently.
I was in the ER yesterday with chest pain and shortness of breath. I do have benign PVCs. However I am unsure if my EKG was fully normal or not although I am pretty sure it was but what has me questioning it is the fact that I was given 4 aspirin and 2 nitroglycerin pills.
My vent rate 126bpm
PR interval 152 ms
QRS duration 76 ms
QT/QTc 306/443 ms
P-R-T axes 71 66 47
Are those all normal?
I do have high blood pressure lately along with an almost constant high heart rate.
I am just concerned that this will forever be a constant worry for him. Any suggestions of how I can help him. Also I asked his MD about having nitroglycerin to have on hand and he said that this wasn't necessary??? Should I insist that we have some available?
The first posting talks about an upcoming phase2b/3 clinical trial in Asia. Yet StudyForhope posted results of a phase3 trial.
Not sure how it works, but a drug company will conduct multiple trials of the same phase before progressing to the next stage?
I'm a Raynaud's Phenomen patients who has the CREST syndrome and i use the nitroglycerin patches to control my raynaud's. Can you tell me if the patches used in this way would cause your acid reflux to be worse. When i took the lowest dose of nitroglycerin patches 0.1 didn't notice any but had to move up and now i do. Will this be something that my body may take an adjustment period for before i notice a different of not having symptoms again?
Those generics are usually cheaper but they must contain the same active ingredient(s), the same dosage form, at the same dose or concentration, and for the same route of administration. The generics are usually cheaper and can use different inactive ingredients and preservatives which can sometimes cause trouble.
Looks like you are getting the generic for from the Israel generic of Effexor. It must be the cheaper generic of Effexor around and maybe it is responsible for your problems.
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