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Nitroglycerin mechanism of action

Common Questions and Answers about Nitroglycerin mechanism of action

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Avatar m tn I am not physically restricted - I walk 1 mile or more day and do 10 minutes of other light exercises most days. My BP runs under 120/80 most of the time. I understand carvedilol helps prevent stiffening of the heart muscle and can help restore LV function to some degree. How specially, so it do this? What is the biochemical mechanism?
712042 tn?1254569209 Despite clear benefits when given acutely, the organic nitrates rapidly lose their hemodynamic and clinical effectiveness when used as sustained therapy, a phenomenon known as nitrate tolerance. The mechanism of nitrate tolerance has been the subject of numerous investigations and much debate.
1098952 tn?1270309713 For instance, many HCM patients have chest pain and shortness of breath—a common symptom of coronary artery disease that is treated with nitroglycerin. If a person with HCM were to take nitroglycerin, the symptoms would worsen and the nitroglycerin could even cause a catastrophic deterioration in the person's condition".
Avatar n tn Female age 50 ... I was being treated for pneumonia with 10 days of levaquin and lodrain 24 D. On the fifth day I started having moderate and continual pain between my sholder blades in the upper back and heartburn (no heartburn for 25 years previously) and extreme fatigue. I thought it was the pneumonia and didn't go to the doctor for five days. My blood test then showed troponin was high, doctor said I may have had a heart attack. Doctor wanted a stress test ... which showed normal.
Avatar m tn The mechanism of action of Campral® (acamprosate calcium) Delayed-Release Tablets in maintenance of alcohol abstinence is not completely understood. Originally, several neurotransmitter systems, including GABA, were investigated for a possible role in Campral's mechanism of action. However, recent evidence suggests Campral's main interaction is with the glutamate system. Chronic alcohol exposure is hypothesized to alter the normal balance between neuronal excitation and inhibition.
Avatar m tn http://www.nasdaq.
Avatar m tn Oyakawa I am in my 3rd year of medical school and I was wondering the mechanism of action of steroid injections in the eyelid causing cataracts. It is not an osmotic agent so why does that occur? thanks so much.
382218 tn?1341181487 Thanks for posting this DV. My favorite part was the mechanism of action for Tecfidera. "Poorly understood...
Avatar f tn Plavix has a unique mechanism of action by blocking the amplification of platelet activation by released ADP, and often used with aspirin to prevent the risk of clots for the first year after DES implant. Plavix and aspirin have different mechanism of action to prevent clots. After a year, plavix is usually discontinue as the risk for clots is decreased, and aspirin is continued long term. The risk of a clot is about 3%.
Avatar f tn If you miss a dose of Nitroglycerin Patch, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once. When used for long periods of time without a break, some people develop a physical need to continue taking Nitroglycerin Patch. This is known as physical DEPENDENCE. Do not suddenly stop taking Nitroglycerin Patch without your doctor's approval.
Avatar m tn HIV is transmitted by; Unprotected penetrative anal and/or vaginal sex Sharing works with other IV drug users Mother to child You never had an exposure.
Avatar f tn Potassium is a chemical element and it is part of the electrolyte that should be in balance with other lytes to adequately conduct an electrical impulse that originates with the sinus node in the right atrium. The mechanism of action is not completely understood, but what is when a voltage (unit of potential for conduction) and electrolyte there will conduction and passage of electrical impluses.
Avatar n tn Well, Viagra is not safe at all in the presence of nitroglycerin tablets and in fact, we know that if anyone takes Viagra with nitroglycerin tablets, that the blood pressure can be lowered precipitously and can be lowered to such levels as can be extraordinarily dangerous to you. [ABC News report from May 2008 - Internet] As we know, not everyone experiences negative side effects from every medication.
Avatar m tn http://www.medscape.com/viewarticle/578705 Ribavirin improves early responses to peginterferon through improved interferon signaling. Gastroenterology. 2010 Jul;139 The therapeutic mechanisms of ribavirin for hepatitis C are unclear. Microarray analyses have shown that ribavirin increases induction of interferon-stimulated genes. We evaluated viral kinetics, serum cytokine expression, and viral mutagenesis during early stages of peginterferon therapy with and without ribavirin.
Avatar n tn Steady-state plasma concentrations of nitroglycerin are reached by about two hours after application of a patch and are maintained for the duration of wearing the system (observations have been limited to 24 hours). Upon removal of the patch, the plasma concentration declines with a half-life of about an hour. If there were to be side effects, it seems it would be within hours.
Avatar m tn I only take isosorbide prior to a workout, and nitro when engaged in an activity that brings on angina. I understand your doctors are suggesting taking isosorbide daily as aschemia does not always produce angina even though the heart cells are not getting sufficient blood supply. This can lead to a silent heart attack so the medication is recommended continuously whether there is angina or not and older people in general are likely to have a silent heart attack.
Avatar m tn While chest pain that gets better with nitroglycerin can be suggestive of agina, there are several other types of chest pain, such esophageal spasm, that can get better after nitroglycerin. Exercise tests and stress echocardiograms are screening test for coronary artery disease. If these screening tests are abnormal, the next step is most likely a cardiac catheterization and angiogram in order to look definitively at your coronary arteries.
Avatar m tn Seeing an orthodontist is advised.
Avatar n tn Some medications are actually derived from plants. The mechanism of action and effect on the body determines the classification, therefore, laxatives can be synthetic or natural.
Avatar n tn "Mechanism of Action Oxomemazine, a phenothiazine derivative, is a sedating antihistamine" The above information is about all I could find on this drug. If it is used in the US, I have no idea what label it's under. Even if I had been able to find more information, I am not qualified to tell you to either stop or start or change any medications. You need to speak with your doctor or chemist for an answer to your question.
Avatar f tn , duloxetine) has a combination mechanism of action involving serotonin and norepinephrine making it useful in depression and also neuropathic pain. When a peripheral nerve is injured there is an increase in pain sensitive fibers leading to increase pain recognition. This causes a change in central (i.e., brain/spinal cord) recognition of pain. One major neurotransmitter involved in this is norepinephrine. Cymbalta works to modulate this change.
Avatar n tn A heart murmur is a sound heard as the blood flows through the heart and especially the blood flow through the heart valves. If there is a defect, a stethoscope hears a specific sound for different defects. ■Angiotensin-converting enzyme (ACE) inhibitors. ACE inhibitors lower the system's blood pressure. The mechanism of action is to relax the blood vessels and that provides less resistance for the heart to pump against and decreases blood pressure.
Avatar f tn boceprevir is in pharmacies now telaprevir should be by the end of the month they both have the same mechanism of action ( protease inhibitors ) and are comparable in efficacy mimi that 70% is for first timers only