I've had chronic, severe nausea for the past year and I can't take it anymore. I get nauseated after everything I eat. It doesn't matter what. I can't even have breakfast anymore (I went from eating solids to drinking liquids, and now I can't eat anything at all). Sometimes I feel like I'm not even hungry, and other times I feel horribly hungry. I can only have small meals now and I can't have dairy or bread.
I might have a solution for you after examining the pharmacology of Nefazodone. To get about the same result you had with Nefazodone with no weight gain I would recommend sertraline (Zoloft) combined with Wellbutrin XL. To get a significant antagonizing effect to your 5-HT2 receptors you would need mirtazapine but it is related with weight gain so I would try the Zoloft with Wellbutrin XL which will basically in a SNDRI like Nefazodone and see how it goes.
I have been taking lamotrigene (the generic for lamictal) for about 10 years. It is an epileptic medication for seizures that is used, as my psych. says, as a mood leveler. It doesn't react to seritonin or anything. it helped take the edginess away for me - but i did put up with blurred vision which i didn't realize was a side effect for years. Went off it last month to see if vision cleared but it was negligible....i take other meds that can cause that too.
My doctor recently put me on Paxil for my anxiety and Panic Attacks. I am 21 years old and have never been the type to take perscription drugs or otc drugs for that matter, so I'm not big on side effects and all that. I have been taking paxil for 4 days now and on day two I realized that I was yawning so much that my jaw was starting to hurt (yawn) I cant stop. Im really really tired and the yawning is getting quite annoying. Is this normal and when does It usually stop?
Anyway, there are lots of options - ranging from a number of medications that have been well studied such as nefazodone, mirtazapine, and the tricyclic antidepressants, to supplements that seem to be effective (although probably somewhat less so) such as hypericum and s-adenosyl methionine. Finally there are a number of medications that are not routinely prescribed for depression that might be of use, and that list is a bit long to put here.
In any event, the answer is yes.
At the time I was taking Nefazodone and recently weaned off of that. I was on 50 mg Z for 3 weeks and was bumped up to 75 mg one week ago. My anxiety has been bad so I am taking klonopin for that. I'm not doing well emotionally and thought the zoloft would work by now since it's been a full month. I also have no desire to even try sexual activity because I know it's not going to be good with the zoloft. My doctor suggested adding 150 mg Wellbutrin.
The interaction has also been reported in patients receiving atorvastatin, lovastatin, or simvastatin with other potent CYP450 3A4 inhibitors such as azole antifungal agents, macrolide antibiotics, HIV protease inhibitors, and nefazodone. Clinically, high levels of HMG-CoA reductase inhibitory activity in plasma may be associated with an increased risk of musculoskeletal toxicity.
Due to the risk of life-threatening and fatal toxicity, patients with renal or hepatic impairment should not be given colchicine in combination with potent CYP450 3A4 inhibitors such as itraconazole, ketoconazole, voriconazole, nefazodone, delavirdine, protease inhibitors, and ketolide and certain macrolide antibiotics. In patients with normal renal and hepatic function, the dosage of colchicine should be reduced when used with potent CYP450 3A4 inhibitors or within 14 days of using them.
t working as well for me anymore, and I wanted to try to switch my meds anyway to improve my sex life. Well, after a rollercoaster of a year where I tried Wellbutrin first, then Nefazodone, then falling into a very deep depression I realized that I really do need to be on Zoloft. The other pills didn't really help my drive, but they did make sex more pleasurable and had quicker/easier orgasms. Now that I am going back, I am devastated to be losing that part of my life again.
(2003, January). Nefazodone decreases anxiety during marijuana withdrawal in humans. Psychopharmacology, 165(2), 157-165.
Haney, M., Ward, A.S., Comer, S.D., Foltin, R.W., & Fischman, M.W. (1999, February). Abstinence symptoms following smoked marijuana in humans. Psychopharmacology, 141(4), 395-404.
Jones, R.T., Benowitz, N.L., & Herning, R.I. (1981, August-September). Clinical relevance of cannabis tolerance and dependence. Journal of Clinical Pharmacology, 8-9 Suppl., 143-152.
my doctor tried putting me on anti depressants last year for anxiety but i refused them because of all the side effects, these included irregular heart, insomnia ect...
I am 38, I had a complete Major Vegatative Depression in 1997, and was more lor less bedridden for 6 months - Nothing worked for me except SERZONE ( Now Called Nefazodone ) I have been on this Medicine for 11 years - I have struggled with Depression BIGTIME and only ever worked for my Father and my Myself, I could work at my own pace and about 20 hours per week for Dad till 2005, then I quit because I was not relaible due to my Symptoms that have always plagued me, I hate the Morning, I sleep ab
It use to be cleaveland heart clinic that I posted on all the time. Now its medhelp. I am having such anxiety right now I cant see straight. I have been posting on the lung forum for some things found on an xray this last week. I dont know how to ask the doctor a question. I keep going to the expert forum and posting and it just goes to the regular forum. It is so discouraging. No one will post back! Does noone post anymore. Do people not want to help anyone out anymore?
Recommended
