Mesalamine pentasa
Common Questions and Answers about Mesalamine pentasa
asacol
the doctor at the time told me that it was the same thing as asacol, however, i found it to be less effective. another doctor later told me that they have the same active ingredient mesalamine, but pentasa reaches a different part of your track... i think asacol stays intact longer, so it gets released lower down in your system.
anyway, i think either of the 2 drugs are mainly for maintenance like the others said.
Japan has not done any drugs trials for this and prescribed oral pentasa to me, which let to an almighty flare. They prescibed pentasa liquid enemas, then steroids liquid enemas, then oral steroids all the while I am getting thinner, but puffier (thanks steroids!), my knees were very painful and my eyesight was blurry. I flew to the UK (nightmare 12 hour flight) + few hour transfer.
I had begun taking medicaton (back then Pentasa), and after a month and a half stopped taking it because it seemed to irritate me more than anyhing else -at first it had cut diahrrea quickly. But it began irritating me (my stomach I think, and my intestines).
Being averse to taking drugs unnecessarily, I stopped completely and never suffered from UC again until 8 years later and the flare up did not occur 'spontaneously'.
During moderate/sever flare-ups I took prednisone orally, in foam suppository as well as mesalamine orally and through suppository. In moderate flare-ups mesalamine orally w/ mesalamine suppositories.
My question is - beyond the general risk that HSV presents - how additionally risky is this for me? It is a possibility that at some point I will have a flare-up that will require immonusuppressive therapy. If I was to contract HSV could my UC symptoms become more severe?
I am 56 year old male, diabetic type 2, have been diagnosed a year ago with ulcerative colitis, they prescribed pentasa as medication, now after one year I for rectal bleeding again, I took pentasa 2000 mg on my own , rectal bleeding stopped, watched my diet for a few days , then I went back to my bad eating habits drinking carrot juice , and tuna with little spices, diarreha came back and today I took 2000 mg pentasa orally, after but was eating sweets , now after a few hours at night bleeding
Her gastroenterologist started her on Mesalamine (4 capsules daily) and later added prednisone 100 mg enemas to try and get the flare-up under control. Things are getting better and she has some of her strength back. There is one puzzling thing that the doctors are not able to pinpoint. This is an intermittent fever that starts in the afternoon and lasts to the night. In the morning the temperature is back to a low 97 degrees fahrenheit and stays stable until afternoon below 98 degrees.
I have suffered from Crohns for 10+ years but only diagnosed last october. My doctor put me on pentasa that I am still on and I've tried numerous times to explain to him it doesn't work. I have daily pain and diarrhea 15+ times a day yet he still won't change my meds. The only test I have had done is a small bowel series which diagnosed it. No other tests to this day. He acts like he doesn't believe me when I say I have extreme pain every day.
He was under treatment and was given Pentasa granules , T PAN (40mg), Tab wysolone and Pentasa Anema. As there was no improvement. Doctor adviced to have Exemptia (Adalimumab) injection. 4 injections (40mg 8ml) was given. Next day he was having stomach pain, tight and rigid stomach, and fast breathing. He was immediately admitted in the nearby hospital and doctor found he was suffering from megacolon (toxic colon).
I had changed from Asacol to Pentasa the week before and the rectal pain had come back-significant burning pain. Went to another doctor and had more bloodwork-borderline IBD tests. Went off Pentasa for a few days in Dec and had severe RLQ pain and right hand pain. Got better after a week back on Pentasa. Had another colonoscopy-essentially negative in late Jan. I continue to have burning pain in my rectum and RLQ and right hand, general fatigue. Stress makes it worse.
I am on Cimzia and Pentasa 4grams a day, for the Crohns itself, Dicyclomine for most bowl and rectal spasms (works in calming down the need to go), and Tramodol 100mg (8 max a day) though I sometimes use more.
Strange thing, the Tramodol acts like a diuretic and with the Dicyclomine, tends to control the pain and symptoms to the point where I am functional again. Although, if it wasn't for the Pentasa and Cimzia , I would be in the hospital or going crazy from the pain and discomfort.
My recent result of biopsy after the colonoscopy indicates epithelial dysplasia. My doctor just advice me to continue taking the mesalamine (Asacol) Do i need an another urgent medication/treatment for dysplasia? What should be my next move?
I have read about a study in which Boswellia was used in conjunction with Mesalamine. My gastroenterologist knows notheing about herbs, but is open to information that I can give her. What is available? Are there any interactions with boswellia and mesalamine that I should be cautious about? Are there any precastions about its use?
Like a lot of people, I probably had it long before I was forced to address the issue. I am currently on Pentasa and 6MP. All seem to be doing okay. However, recently I have been having a hard time swallowing. I can actually feel everything in my throat. Has anyone else experienced the same? I hate to go through any tests if anyone has suggestions. Wishing everyone long remissions!
This was after many different tests for different things. I was on Prednozone and Pentasa at first. I am still on Pentasa 8 times a day and many other meds. Mostly for pain, cramps and bleeding. Go to the crohns.com web site and after signing up, they will send you a wonderful book that answers many questions. I am glad to help and answer concerns. That's how we help each other. Please ask anything. It's like having a baby, all modesty is out the window.
He prescribed her half a tablet of Tryptizol every night before going to bed against nausea and one Pentasa Sachet every night before food against irritated bowel disease.
Moreover, she did a Gastroscopy which didn't show anything.
Can anyone of you help or might have had a similar experience? Is the doctor right with his treatment suggestions? She is also on the pill (Yasmine) which she started only in May though but wasn't taken while she was in Canada and the pain subsided.
i have uc 2 years ago i have no diahrea no belly pain just some time see some blood when i go to bath i take pentasa 4 pills per days for 8 mounths i i didn't see any blood from the first 10 days when i started to take pentasa i stopped to take it 7 mounths but then the bleeding back then i started to take pentasa again but since 3 months but bleeding never stop come and god ,,,i heard that vitamin D, yoghurt , banana, fenugreek,tumeric..
Hi there,
I was diagnosed with sigmoidal colitis in 2005, but I reckon that it went unchecked for about 4 years prior to that. I was initially treated with mesalamine (Asacol) but it had no effect. My GI guy then hit me with prednisone and that knocked it down. I have been on Asacol in a prophylactic capacity since (800mg tid). Does it keep me in remission. Maybe, but maybe it is the tremendous quantities of fentanyl, diacetylmorphine and morphine I abused as well for all I know :P.
In combination with the Pentasa he is now clear thank god. Since then my aunt got ulcerative colitis and she was given different medication. We sent her the fangocur to take also. She tried for a couple of days and noticed an improvement in her stools but as she was much older she didn't like the taste and stopped. Unfortunately she now has crones disease. My daughter now has the same symptoms, her stomach is aggravated and her stools are bloody and passed a clot yesterday.
What other symptoms are present? Mesalamine or Canasa suppositories works by preventing the production of substances that cause the inflammation of the colon. The usual side effects include diarrhea; dizziness; gas; hair loss; headache; mild stomach discomfort or pain; and nausea. The sour taste could be indirectly related especially if you have other gastrointestinal issues like acid peptic disease or gerd.
Did the doctor take her off the meds? If it was antibiotics then yes she would be off. However, since she was so sick I can't imagine why the dr doesn't have her on pentasa or some other meds to prevent flare-ups.
If she just stopped the meds herself and it was a pentasa type of med and not just antibiotics she is asking for trouble.
There have been a few cases of liver failure possibly related to the use of mesalamine (the active ingredient in Asacol HD), but I haven't read anything about fatty liver as a side effect.
A fatty liver, it takes between 6 months and 2 years to fully reverse. Dr Sandra Cabot's article "Fatty Liver - What Is Fatty Liver And How To Reverse It?
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