imatinib trials

Eithne01, The treatment of chronic myeloid leukemia (CML) has changed significantly since the late 1990s, with the development and subsequent approval by the Food and Drug Administration of imatinib (in 2001), the first of a class of medications called tyrosine kinase inhibitors, which target the specific abnormality that causes CML. Before that time, patients were treated with other therapy, including interferon and bone marrow transplant, and had very poor outcomes.

It is possible that the white blood cell count would normalize after 2 weeks of taking Imatinib (Gleevec). Most responses to Imatinib are rapid since it targets the molecular pathogenetic event in CML. You may seek a second opinion if that will give you a peace of mind. Good luck.

lots of people die all the time because they reject traditional treatments and go with 'natural' things instead I would think of using alternatives along with regular treatments, but not in place of them. Some alternative things might have some benefit. Isn't homeopathy the approach where you dilute some substance down to one part per billion or so, and then expect it to actually have some curing power?

Are you currently on any medication like imatinib? The neutropenia can be due to your current medication. You can ask your hematologist for G-CSF injection if you have persistent neutropenia. Patients with CML are immunocompromised and can easily acquire infections. Neutropenia also puts a patient in an immunocompromised state. For now, it is very important to prevent acquiring any infection. You should avoid crowded places and persons with ongoing infection. Good luck.

Hi. Chronic Myelogenous Leukemia (CML) is a blood disorder caused by an acquired genetic defect in the pleripotent stem cell. It has several phases: indolent chronic or stable phase, aggressive or advanced phase, and accelerated and blastic phase. The transition between phases may take years (on the average, 4 to 6 years from the stable phase to aggressive phase).

Average survival rates are generalizations, not applicable to a particular patient. The prognosis is relatively good. Newer techniques are being tried, including imatinib and stem cell transplantation. All the best, and God Bless!

How do I find out about trials?...will my doc tell me and ask if thats something I'm interested in them or do I have to find them for myself?...Im just wonderinf...

i was on a trial for virimadine so i was treated with that and interfuron... would i be eligible for any of the new trials for non-responders ? im guessing no because i have absolutely no results from this trial they told me NOTHING except after 6 months it wasnt working and they stoped it... i could try and get on a new trial for treatment naive and i guess i could just lie and say i never treated...

I was wondering if anyone knows of... or could direct me in how to find trials for non-responders in the southern California area.

I was in the last boceprevir trial. Like epiphiny says, it is to get a baseline and suitability. It's all pretty standard in trials and would be a good idea for most people starting TX, too. To be honest interferon can cause bizarre problems like lung damage, heart palpitations, etc. Not too common, but it happens.

was screened for 3 trials and excluded at thge last second [it seemed] because of my early cirrhosis ... on 3rd week of BI 201335 trial..so hang in there......patience is a virtue..

t be included in the trial. So to answer your question, there are very strict guidelines relative to clinical trials. As Bill said, go to the website and read some of the trials.

Are there any new trials other than interferon or ribaviron, I've relasp twice and there nothing else my Doc says he can do.

TY for the reply. Yes I was told and am thinking that its parasitc or allergy. I went to aruba in June but that wouldn't have an affect on me now, would it?

Since its a school they ask patients who qualify to volenteer for drug trials when they are avalible. I was asked to take part in one that is for a nausea medication. So basically when i go in for my c section they will admister the medication or placebo when i get the spinal/epidural before the surgery. I would really like to take part and volenteer but at the same time id rather not be puking while they are cutting me open....

hi -- a few weeks ago there was a guy who posted here looking for user-friendly clinical trials sites. He was getting medical help outside of the U.S. I can't find his post....so thought I'd write a new one hoping he'll find this. I found this site today and thought of him. http://www.centerwatch.com/patient/pns/patemail.

Is anyone doing clinical trials? I think i would go anywhere for relief and / or a cure!

I am looking to find treatment I have no insurance and I see a lot of Clinical Trials that you can sign up for an be notified by a recruiter, but my thought is how do I know if they reputable. Who can I contact to find out?

Except for the clinical trials as far as I know there is not yet any treatment available for HCV without interferon. For genotype 1, I believe it will be a few years before anything is available. By the way your English is fine.

t know if I can post this or not, so will not post the actual information yet, but I received a magazine from a very good hospital in my area and in it was information about the ovarian cancer clinical trials that they are doing and a number to call if someone is interested. I live in Central Florida. So, if it is ok to post that info, or if there is anyone on here that would like that info, you can always send me a message.

i would really like to find a web site that line items in a simple way what trials are out there..and explains a little about each one...something that could be printed off...i also see dmhrdh did 48 weeks..what about the 24 week trials..seems like somewhere this list has to exist....or maybe someone here could list them....thanks....

Its a great resource. I also recently found a site that matches patients to trials, http://trialx.org.

Anyone know of any current clinical trials for genotype 1 relapser in central/southeast Florida?

be well, have strength, get healed.

So because of this I have called Duke University to see about getting in their clinical trials which I could start right away. I would like some feedback good and bad but in the end I realize its my decision. This waiting game has put my life on hold and affecting me financially only. thanks everyone for your response. I enjoy and respect all of you.

Sorry to hear this happened, and what a good question you raise. I'm not in a study; I declined a couple of treatment trials for practical reasons (travel involved). I did go over the consent forms I would have signed if I'd participated, but don't recall anything specific on this topic. It would be handled differently here, regardless. Provincal health insurance would cover a medically necessary procedure regardless of the cause. I would think in a situation like this, in the U.

Imatinib trials

Common Questions and Answers about Imatinib trials

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