imatinib neuropathy

Eithne01, The treatment of chronic myeloid leukemia (CML) has changed significantly since the late 1990s, with the development and subsequent approval by the Food and Drug Administration of imatinib (in 2001), the first of a class of medications called tyrosine kinase inhibitors, which target the specific abnormality that causes CML. Before that time, patients were treated with other therapy, including interferon and bone marrow transplant, and had very poor outcomes.

It is possible that the white blood cell count would normalize after 2 weeks of taking Imatinib (Gleevec). Most responses to Imatinib are rapid since it targets the molecular pathogenetic event in CML. You may seek a second opinion if that will give you a peace of mind. Good luck.

lots of people die all the time because they reject traditional treatments and go with 'natural' things instead I would think of using alternatives along with regular treatments, but not in place of them. Some alternative things might have some benefit. Isn't homeopathy the approach where you dilute some substance down to one part per billion or so, and then expect it to actually have some curing power?

Are you currently on any medication like imatinib? The neutropenia can be due to your current medication. You can ask your hematologist for G-CSF injection if you have persistent neutropenia. Patients with CML are immunocompromised and can easily acquire infections. Neutropenia also puts a patient in an immunocompromised state. For now, it is very important to prevent acquiring any infection. You should avoid crowded places and persons with ongoing infection. Good luck.

Hi. Chronic Myelogenous Leukemia (CML) is a blood disorder caused by an acquired genetic defect in the pleripotent stem cell. It has several phases: indolent chronic or stable phase, aggressive or advanced phase, and accelerated and blastic phase. The transition between phases may take years (on the average, 4 to 6 years from the stable phase to aggressive phase).

Average survival rates are generalizations, not applicable to a particular patient. The prognosis is relatively good. Newer techniques are being tried, including imatinib and stem cell transplantation. All the best, and God Bless!

TY for the reply. Yes I was told and am thinking that its parasitc or allergy. I went to aruba in June but that wouldn't have an affect on me now, would it?

I have burning in the bottoms of my feet, as well as neuropathy in feet and hands. The neuropathy is caused by years of untreated pernicious anemia, so if you haven't been tested for B12 deficiency, you should ask your doctor to do so. I'm not sure about the burning in the bottoms of my feet. I don't think it's thyroid related, but at this point, I can't say.

I am 2 chemos away from finishing my round of six and have developed peripheral neuropathy in my hands and feet. I am on 300mg Neurontin 3 x a day and it still seems to be getting worse. The pain keeps me from walking long distances and I cannot hang my hands down; I have to keep my elbows bent. I have also tried acupuncture. I use warmth to alleviate the pain but it is only a temporary relief. Any ideas or experiences?

hi hubby on wk 14 of triple tx they say it will stop his perpheral neuropathy getting any worse which is why he agreed to have the hep c treatment in first place because he got no other symptoms normally associated with hep c his scan and liver function tests are more then alright for a 61 yr old and has you good folks out there you know this treatment is very hard for all concerned any info will be greatly appreciated many thanks

Hi, Benign neuropathy is usually the treatable form of neuropathy. It occurs mainly due to diabetes or B12 deficiency. It can be controlled by maintaining the sugar levels in the normal range and by B12 supplementation.

I have type 2 and have developed severe neuropathy throughout my body. My weight is normal I'm 45 years old. This last year has been very hard because I'm falling a lot and it has advanced to a point where it's very difficult to walk at all. I don't have insurance so getting the proper care is hard. I recently admitted to myself that I'm no longer able to work and I'm in the process of filing for disability. The question I have is this.

I am a T1 dibetic x 39 years. I also have neuropathy (focal, peripheral and autonomic). I have not tried Lyrica. I am using neurontin. These drugs take a while to build up in your body. To tell you the truth, I take a cocktail of medicines...for the pain I use neurontin 300-1,200mg. depending on the time of day, motrin 800mg, and nortryptiline as needed when the pain gets really bad. The latter is an antideppresant that is also used for pain management.

Male friend had brain surgery. He was left with chronic venous insufficiency and neuropathy. He can't walk because of this. What can he do to stop the severe burining sensation on both of his legs?

Is there cure? Or a way to bring it under control? The doctor ran a series of tests: doppler, blood work,nerve testing, etc. He said "Neuropathy w/ unknown diagnosis" Put me on very low dosage of Gabamtin (sic) and Hydroxyotin (sic) Then told me to get tested for diabetes in six months. My feet, especially left foot -- numb, cold painful toes, pain in the balls of both feet. It feels like it is starting to affect my hands.

i have a friend that has neuropathy in his feet. he has no feeling at all. i really mean not at all.one foot is swollen now and has seen five doctors and all sad they are unable to find anything wrong.is it common for hat to happen? he is very frustrared with not being able to find out what to do. could you please give me an input.thanks This discussion is related to <a href='http://www.medhelp.org/posts/show/297546'>Ongoing neuro symptoms. No answers :-(</a>.

I was diagnosed in June of 2007 and have had pretty good BGLs since changing my diet. My question is, these little shocks in my figers and toes and hips, are they normal? I haven't had a 200 day or night since November last year and don't get really bad lows either but these things are driving me nuttier. My dr says it's nothing to worry about, just a little neuropathy. Is that a real diagnosis?

She said the burning sensation in my feet was neuropathy. Does anyone else suffer from this? She also said the itching is an excess amount of Billiruben (spelling ?). And to my dismay there is not an anti-billiruben pill. LOL She ordered an ultrasound, my liver is enlarged and feels like it is pushing my ribs. Just to make sure there were no other issues. And she wrote the orders for my RNA and PCR.

About 5 months ago.I developed neuropathy in my thighs & arms. I was tested for a bunch of things and the only that was a red flag was vit d deficiency . Could vit d caused all this?

I have pain associated in Diabetic Neuropathy in my feet. I have started taken Gabapentin for the pain. Will Gabapentin effect my blood sugars?

I think what you do have is some neuropathy. I also had chemo, and got neuropathy from that, a fairly common event in some chemo people. It subsided in my hands over many months after chemo was done, but my feet still are rather affected. Next time you are scheduled to see your cancer doc, obviously mention this to him, he may be able to prescribe something to ease the discomfort in your hand.

Hi Im a 29 year old male who had insulin resistance. I had neuropathy that affect me greatly at 19 to the point I could not walk. When I turned 24 it came back and I've been dealing with it ever since. It has gotten so bad its affecting Urination and my bowls and its affecting my reflexes. I went to a neurologist and he says I have difficulty walking in tandem. My a1c is 5.3. Could this be diabetes.

Imatinib neuropathy

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