Eithne01,
The treatment of chronic myeloid leukemia (CML) has changed significantly since the late 1990s, with the development and subsequent approval by the Food and Drug Administration of imatinib (in 2001), the first of a class of medications called tyrosine kinase inhibitors, which target the specific abnormality that causes CML.
Before that time, patients were treated with other therapy, including interferon and bone marrow transplant, and had very poor outcomes.
However when i moved from Atlanta they insisted on a bone biopsy that said no to Mastocytosis. All my Atlanta drs said Mastocytosis explained everything including my reoccurring pericarditis. So if its not Mastocytosis, what is it. They offered nothing here in Chattanooga, so I dont know what is wrong with me.
dear doctor, can you please tell where we can treat Mastocytosis, the baby was born with it and it's 2 months old now, he was born with swollen liver and spleen and he was treated only after a month with antihistamine, we are in Macedonia.
Are you currently on any medication like imatinib? The neutropenia can be due to your current medication. You can ask your hematologist for G-CSF injection if you have persistent neutropenia. Patients with CML are immunocompromised and can easily acquire infections. Neutropenia also puts a patient in an immunocompromised state.
For now, it is very important to prevent acquiring any infection. You should avoid crowded places and persons with ongoing infection.
Good luck.
Hi.
Chronic Myelogenous Leukemia (CML) is a blood disorder caused by an acquired genetic defect in the pleripotent stem cell. It has several phases: indolent chronic or stable phase, aggressive or advanced phase, and accelerated and blastic phase. The transition between phases may take years (on the average, 4 to 6 years from the stable phase to aggressive phase).
She stated that non sclerotic may suggest that the lesions were not benign and is sending her to a pediatric orthopedic doctor. My daughter has a history of systemic mastocytosis that affects her skin and presents with hives. She has not had an episode in over a year and is other wise healthy. Her growth is on track and she doesn't consistantly complain of pain in this region.
m too young to have all these problems I asked my new Dermotolgist about Mastocytosis. Did a biopsy of rash on belly.Still waiting for results. He said it may or may not be Mastocytosis but I definitely have too much histamine. I'm up to 4-10mg of Atarax a day so I can function again. Still having flares on 3 so we'll add a pill a week until we find the right dosage. So my question is what else could cause too much histamine and all those problems.
Mpox is not only transmitted by touching, but is also transmitted by respiratory droplets. If the children in your life are immunocompromised, wearing a mask would help.
Have you googled symptoms of mpox? You can avoid contact with anyone who has a rash, but people are contagious 1-4 days prior to symptoms.
Honestly, I'm not sure why you've latched onto mpox.
My daughter has Mastocytosis, was a hair stylist for over 20 years, all the chemicals she breathed in has caused her to be allergic to almost everything.
If you breathe it...you eat it.. it's in your body.
I have no idea how your question has come to be on the Mastocytosis Board but, I'm not sure if you have something serious or not. Contact your doctor and go in and get a check-up and let her/him know what is going on and see what their thoughts are. Good luck!
Average survival rates are generalizations, not applicable to a particular patient. The prognosis is relatively good. Newer techniques are being tried, including imatinib and stem cell transplantation.
All the best, and God Bless!
Hello,
I have seen an allergist and blood tests came back negative for allergies. He suspects urticaria pigmentosa/mastocytosis. I don't feel I have the intense itching that is described....but some of my other symptoms seem to fit mastocytosis. I am waiting on the skin biopsy results to see if that is the diagnosis. This is not encouraging to me. I really was hoping for a food allergy...something I can intentionally avoid.
Malignancies either associated with or thought to be associated with activated tyrosine kinase enzymes include hypereosinophilic syndrome, systemic mastocytosis, chronic myelomonocytic leukaemia and dermatofibrosarcoma protuberans.
Hope this helps. Please let me know if there is any thing else and do keep me posted. Take care!
I take Hemocyte-plus for anemia and Synthroid for hypothyroidism. I have recently been diagnosed with systemic mastocytosis. I have many other symptoms as well, so I'm not saying that this is what you probably have, but in trying to get diagnosed, I was tested by an endocrinologist first. Your endocrinologist may find some things that could lead to a proper diagnosis.
Anyone familiar with Mast Cell Leukemia? I see a topic for this under mastocytosis forum, but no posts.
I am trying to identify the medical experts and cancer centers that specialize in this very rare cancer.
TY for the reply. Yes I was told and am thinking that its parasitc or allergy. I went to aruba in June but that wouldn't have an affect on me now, would it?
**Read below - but please look into: Mastocytosis (www.tmsforacure.org) as this might also be a cause, that is a rare but "controllable" disease. I have yet to receive my results from this test, but will have them within the week.
I am 25/f and have had severe pain for the past two and half months. symptoms have included:
- RUQ Pain - travels through back (not to shoulder) sometimes wraps around the side.
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