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Imatinib formulation

Common Questions and Answers about Imatinib formulation

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Avatar f tn Eithne01, The treatment of chronic myeloid leukemia (CML) has changed significantly since the late 1990s, with the development and subsequent approval by the Food and Drug Administration of imatinib (in 2001), the first of a class of medications called tyrosine kinase inhibitors, which target the specific abnormality that causes CML. Before that time, patients were treated with other therapy, including interferon and bone marrow transplant, and had very poor outcomes.
Avatar n tn It is possible that the white blood cell count would normalize after 2 weeks of taking Imatinib (Gleevec). Most responses to Imatinib are rapid since it targets the molecular pathogenetic event in CML. You may seek a second opinion if that will give you a peace of mind. Good luck.
1004138 tn?1316251113 lots of people die all the time because they reject traditional treatments and go with 'natural' things instead I would think of using alternatives along with regular treatments, but not in place of them. Some alternative things might have some benefit. Isn't homeopathy the approach where you dilute some substance down to one part per billion or so, and then expect it to actually have some curing power?
Avatar n tn Are you currently on any medication like imatinib? The neutropenia can be due to your current medication. You can ask your hematologist for G-CSF injection if you have persistent neutropenia. Patients with CML are immunocompromised and can easily acquire infections. Neutropenia also puts a patient in an immunocompromised state. For now, it is very important to prevent acquiring any infection. You should avoid crowded places and persons with ongoing infection. Good luck.
Avatar n tn Hi. Chronic Myelogenous Leukemia (CML) is a blood disorder caused by an acquired genetic defect in the pleripotent stem cell. It has several phases: indolent chronic or stable phase, aggressive or advanced phase, and accelerated and blastic phase. The transition between phases may take years (on the average, 4 to 6 years from the stable phase to aggressive phase).
Avatar f tn Average survival rates are generalizations, not applicable to a particular patient. The prognosis is relatively good. Newer techniques are being tried, including imatinib and stem cell transplantation. All the best, and God Bless!
Avatar m tn Tenofovir alafenamide (TAF), a new formulation that reaches higher levels in cells but allows for lower dosing, was as effective as the current tenofovir disoproxil fumarate (TDF) formulation but had less impact on markers of kidney function and bone turnover, researchers reported at the 53rd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2013) this week in Denver.
Avatar f tn According to Pharmaceutical Formulation Databases and Resources, lubricants in medication tablets help keep the medication powder from sticking to the equipment used to make the tablet. Dextrose and microcrystalline cellulose are inactive ingredients used in Armour Thyroid tablets. According to Pharmaceutical Formulation Databases and Resources, these act as fillers and compression aids to improve the overall characteristics of the tablet powder.
Avatar n tn The answer is no, however the differences are probably not clinically significant. Valium is a brand name. Not a generic name. The generic name is diazapam. The FDA will usually provide a history of changes, although some may be proprietary. You ask an interesting question. Many "common" drugs have actually changed in formulation several times. Synthroid, for example, has changed it's formulation several times since introduction.
Avatar f tn (Datum: 19.September 2011) Knauer J, Krupka I, Fueldner C, Lehmann J, Straubinger RK. "Evaluation of the preventive capacities of a topically applied azithromycin formulation against Lyme borreliosis in a murine model." J Antimicrob Chemother. 2011 Sep 15. Our data indicate that topical treatment with a formulation containing azithromycin is a promising approach to prevent Lyme borreliosis shortly after a tick bite.
606423 tn?1271824088 Are you happy with the new Armour formulation? I guess they changed their formulation or something along thos lines and thats why there is a shortage. A lot of us have switched to other natural brands such as Westhroid and Naturethroid.
Avatar f tn Hi, welcome to the forum, your history is suggestive of that you may be having drug allergy to vitamin formulation. You may be hypersensitive to any component of the formulation. From your history it is suggests that you are intolerant to formulations of vitamin esp. if lactose or lactose like base is used. You need to discontinue the vitamins and go for other brands having different components. See whether you are comfortable with the new drug.
Avatar f tn ve been eating something pervasive, using the old-fashioned Listerine (the stinky kind) and then rinsing it off with water. Something about the formulation (made for use in the mouth, of course) seems to cut that sort of oily sweat that comes from highly aromatic food. You might try it on your underarms. Just rinse it off afterward of your armpits will smell like Listerine, menthol and eucalyptus.
Avatar m tn If you have used a gel based formulation in the past, try a cream based formulation. Continue using a lot of moisturizer. Please see a Dermatologist for a prescription as potent steroids are not available over the counter. Hope that this information helps and hope that you will get better soon. Best Regards Dr.
Avatar m tn Hi, welcome to the forum, your history is suggestive of that you may be having drug allergy to vitamin formulation. You may be hypersensitive to any component of the formulation. From your history it is suggests that you are intolerant to formulations of vitamin esp. if lactose or lactose like base is used. Abdominal bloating can also be seen due to hyperacidity, air swallowing or intolerance to other foods like gluten, certain wheat etc.
Avatar n tn I have heard a lot of people complain about the new formulation of Oxycontin .It is called OP I think .Purdue made this new formulation to stop people from abusing it but I have heard a lot of CP patients complain that it doesn't work as good as the old formulation .There is a substance that turns to a gel to keep people from snorting it or shooting it up and that may be what is causing it to not dissolve correctly .That's my best guess about it though .I would talk to my Dr about this .
Avatar f tn TY for the reply. Yes I was told and am thinking that its parasitc or allergy. I went to aruba in June but that wouldn't have an affect on me now, would it?
Avatar f tn t necessarily work for you, that something as simple as switching to the LIQUID formulation of the exact same product is the perfect solution and works like a charm....and helps whereas the other formulation maybe didn't....that's why i was asking FLADDICT about that liquid formulation from GNC....i guess i (and sarah) could always call GNC and ask them, too....they should know their products....
Avatar n tn A while after it was reformulated, the FDA stopped production and shipments for several months, many people switched to other brands at that time and never went back. I used the new formulation for several months before it became unavailable nation wide. It is believed that the new formula which uses micro crystalline cellulose as a filler (Nature Throid changed to that as well), makes the hormone not absorb as well.
692143 tn?1275836577 My medication is Armour Thyroid, which was working for me, until recent change in formulation. Recently had TSH tested, and I was high on the range. Meaning, the higher the number, the lower your thyroid function. My test showed 6.1. Physician wants me to wait 3 full months to be retested and has increased my dosage by 15mg (1/4 grain). I've been on this increase of dosage since 4/15/10. My hair is falling out, my skin is seriously dry/flaking, gained 10 lbs.
Avatar n tn If the tablets are consistently not breaking down in your GI tract, then you might want to discuss other medication options with your gastroenterologist. Salofalk is one of them, another is Colazal. There is also a new time-release, once per day formulation of mesalamine on the market called Lialda. The matrix of that formulation may be better tolerated in your GI tract. Bottom line is that you have options. I wish you well, IBD is a total drag.
Avatar m tn But today i did urine RE and there is 4-6 calcium oxalate crystals. Is there anything wrong? What should i do to prevent formulation of renal stone? My blood report shows 36 ESR(westergren) and 11300 Total Leucocyte count . If there any problem in Kidney??
Avatar m tn It is a Nutritional supplement marketed for dry eye patients. From Science Based Health: "HydroEye is a patented oral formulation that provides continuous relief for dry eye discomfort. HydroEye contains a proprietary blend of omega-3 and omega-6 fatty acids, antioxidants, and other key nutrients that work together to support a healthy tear film.
Avatar f tn It appears you are referring to an immediate-release tablet formulation of acetazolamide 250mg. it is safe to split the immediate-release tablets. Extended-release capsules should not be broken.