Eithne01,
The treatment of chronic myeloid leukemia (CML) has changed significantly since the late 1990s, with the development and subsequent approval by the Food and Drug Administration of imatinib (in 2001), the first of a class of medications called tyrosine kinase inhibitors, which target the specific abnormality that causes CML.
Before that time, patients were treated with other therapy, including interferon and bone marrow transplant, and had very poor outcomes.
I am aware of dermatofibrosarcoma protuberans (DFSP). I am still awaiting a pathology report. My question is can a good dermo doctor tell the difference between the two and it is normal for a biopsy to be checked by 2 doctors. I requested the surgically removal and my dermo did not seem concerned it was cancer. Thank you.
Are you currently on any medication like imatinib? The neutropenia can be due to your current medication. You can ask your hematologist for G-CSF injection if you have persistent neutropenia. Patients with CML are immunocompromised and can easily acquire infections. Neutropenia also puts a patient in an immunocompromised state.
For now, it is very important to prevent acquiring any infection. You should avoid crowded places and persons with ongoing infection.
Good luck.
Hi.
Chronic Myelogenous Leukemia (CML) is a blood disorder caused by an acquired genetic defect in the pleripotent stem cell. It has several phases: indolent chronic or stable phase, aggressive or advanced phase, and accelerated and blastic phase. The transition between phases may take years (on the average, 4 to 6 years from the stable phase to aggressive phase).
Average survival rates are generalizations, not applicable to a particular patient. The prognosis is relatively good. Newer techniques are being tried, including imatinib and stem cell transplantation.
All the best, and God Bless!
When the pathology report came back it was cancer. It was a type of rare cancer called dermatofibrosarcoma protuberans. I had a surgical procedure called a wide excision done a few weeks ago and I'm doing well. These type of tumors often start on a limb (arm or leg) and I would encourage you to have it removed and sent off to be sure it isn't something that may need further treatment. I don't want to scare you. What you have going on may be nothing related to this.
When they removed it, the pathology report came back showing a rare type of cancer called dermatofibrosarcoma protuberans. This is a very slow growing cancer, but locally aggressive. I had to have another surgical procedure called a wide excision to remove more tissue and hopefully all of the tumor that was underneath the skin.
What are the chances this is cancerous? I do have a history of a malignant cancer, had a dermatofibrosarcoma protuberans tumor on my scalp which was removed in 2008. Have scheduled a follow-up appt. as my primary Dr. suggested, but this time w/ an endocrinologist. What should I expect at that appt. or what should I request be done? Sorry for the length of this post and thanks in advance for your time!
TY for the reply. Yes I was told and am thinking that its parasitc or allergy. I went to aruba in June but that wouldn't have an affect on me now, would it?
Therapy with corticosteroids is used for the treatment of most and additional therapy is available and dependent upon the type of HS. Newer medicines such as imatinib and mepolizumab are said to be promising. So, should your son have HS, there is reason to be optimistic regarding a positive response to currently available therapy.
You should request, of his doctor, an additional explanation for the tentative diagnosis of pre-hypertension.
Good luck.
Chronic Fatique syndrome, fibromyalgia, Irritable Bowel Syndrome, Interstitial cystitis, Asthma, Narcolepsy, mild sleep apnea, Dermatofibrosarcoma protuberans, arthritis, degenerative disk disease, GERD and depression. Two other times I have been worked up for MS, both times they said that it must just be CFS acting like MS. This was the first time the MRI had anything abnormal.
Patients with hypereosinophilic syndrome should be tested for the presence of the FIP1L1-PDGRFA-mutatition in order to identify patients that could benefit from a treatment with a tyrosine kinase inhibitor such as Imatinib. At present, immunosuppression is still the treatment of first choice for Churg-Strauss syndrome. Novel treatment modalities for both diseases include immunomodulation with interferon alpha and biologics such as antibodies against interleukin 5.
PET CT SCAN mentioned no metabolically alive cells, As precaution I was put on Imatinib for last 4 months. LFT was normal for first 3 months, This month I have raised SGOT & SGPT LEVELS & also HBV Ag is positive ( Was Negative in test done before my Surgery).Should I continue on Imatinib or need to go for a second opinion. What is the course duration & Will this HBV ben cured.
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