humira with methotrexate

I have had Crohn's for 40 yrs; 30 yrs on steroids, 10 on methotrexate. Originally oral, 25 mg a week, but last 4 yrs weekly injections of 25 mg. I had a hemi-colectomy in March 09, with 15 cm of my small and large intestines removed. Unfortunately, I then had a big flare in late September requiring 2 weeks again in hospital. I was put on remicade: gastro said I would have only 3 infusions: 0, 2 weeks, 6 weeks, but still had faecal incontinence and failure to put on weight.

I have been taking injections of Methotrexate and Humira once a week since late May. The combo of these two drugs has taken me out of my flare up, which lasted a year, and allowed me to avoid surgery. I didn't see vast improvements until November, so it did take a while to really get me back to healthy but it was worth the wait. Good luck to you and I hope you are feeling better already.

I have RA and use Humira/methotrexate. How long do I have to be off Humira to get a yellow fever (and/or tyhphoid) vaccine? How long to I have to stay off Humira after the vaccine?

Both are supposed to do the same thing in the body. The only difference is Remicade is a made-protien where as the Humira is a human protien. With Humira you give yourself a shot every other week. So far, after using both, I prefer the Remicade. I didn't mind the treatments as much as I do the Humira even though the Humira is more convienient (I hate having to give myself a shot.

The first was Prednisone, then ASA, then another, and finnally Methotrexate and prednisone together which seemed to help tremedously. I weened myself (with Dr recomendation) off of the prednisone after the symtoms went away and continue to take the Methotrexate. It seemed as if the crohn's was in remission for about 6 months, but I have recently had a flare-up.

I have been treated for rheumatoid arthritis with Humira for 7 months including a combination of Humira and methotrexate for the past 2 months. I also take 5mg of prednisone, and 6 Azulfadine tablets each day. I was taking Humira once every fourteen days and I am on 15mg of methotrexate a week. About a month ago, I started experiencing numbness in my toes and feet. I mentioned it to my rheumatologist but she wasn't concerned and simply told me it wasn't rheumatoid arthritis.

Like clockwork, I am sick for one to two days after I take my methotrexate and Humira. Every other week, I get severe nausea and upset stomach. I usually have to take something for nausea but that then will be make me extremely sleepy. The nausea starts about 12 hours or so after the shot. Is this normal? Does anyone else experience this? I have been on each of these meds for 4 years now.

m now taking Plaquenil, Methotrexate and Humira Injections. My Rheumatologist did not discuss this with me. He said that the progression needs to be stopped before even thinking about it, but I was just wondering what kind of surgery is available out there and if there were any success stories. I have bumps under my feet and the feeling I get while walking when I flare up is like walking on marbles. I was wondering if surgery would help eventually and how long is the healing process etc. Nat.

I had the same concerns and fears when I started on methotrexate. I should learn Wednesday whether or not I will be joining the Humira club this month or postponing it again. We are taking it a month at a time. Glad you found us and I look forward to hearing more from you.

The response is correct....you are not supposed to drink alcoholic beverages while taking methotrexate...I was on the same dose as you and my rheumy said no alcohol...some rheumies will allow a certain number of drinks per year...like 1 drink on a special occasion...recommend you contact your rheumy if not already done, as s/he should have provided this direction to you...it's to avoid liver damage...I've since been put on other RA meds, but still can't drink...

I take methotrexate and stopped this when the severe diarrhea started. I live with watery diarrhea because of methotrexate. I have psoriatic arthritis and take celebrex,and Humira also. Are they looking for cancer in these lesions? What is a lesion?

I've been diagnosed with RA since 2006. On Methotrexate 20mg, Humira, and folic acid. In last 24 months I've had 3 bouts of pancreatitis (twice after gall bladder removal) with no cause determined gastro doc, and chronic burning sensation in legs, buttocks and lower back. (Similar to feeling of frostbite) Sensation increases as day progresses and greater sensitivity on sitting or clothes binding in areas.

I am a 19 year old female and I was diagnosed with Psoriatic arthritis and Akylosing Spondylitis. I have had Henoch-Schonlein purpura since I was seven and have dealt with severe infections since then. I know that the drugs I will have to take weaken the immune system, but I am curious as to how much...I am a college student and I don't want to have to worry about being sick all the time.

t work for you, has your gastro thought about changing to a different anti-tnfa immuno-suppressant, such as Humira or Cimzia? Otherwise, you might like to think about methotrexate - I have recently come off it after 9 yrs, and it worked well until I had an allergic reaction the day after my Remicade infusion, so we have discontinued it.

Hello everyone, hope this posts finds you all well. I was hoping someone might have a trick to make taking the humira injector pen any less painful. I'm actually hoping I can talk my doctor into letting me get it in vial form so I can fill my own syringe and take it the same as I do the methotrexate. But that pen, its a killer. I always let it warm up from the fridge first is this a mistake maybe? Does it just burn naturally or does the injector pen make it worse?

I've had Crohn's all my life but only diagnosed in 2007. I am in the midst of having a flare and have been for the past 4/5 months! i have seen my consultant and he has decided to put me on Humira at home which i am glad as i don't have a car to go to the hospital every 2 weeks. So i am kind of happy. Basically I was wondering about surgery as I have read many good reviews on re sectioning.

I started on plaquenil and then went to methotrexate. After awhile, I stopped the methotrexate and discovered the plaquenil was managing my symptoms fine (unless I do not get regular sleep, get stressed out and/or it rains - then I go into flare.) Prednisone was not something they used for me, but I did have several steroid injections to deal with my most troublesome spots. How is your daughter doing now? When is her next shot?

I thought I had the flu about 5 years ago.. turned out to be PMR and my joints were very painful.. could hardly walk.. it was in my feet and ankles, knees, and wrists.. anyway I took celery seed and Ibuprophen.. and it went into remission.. yeah! celery seed.. worked as well as the sterioids that others have been on.. and though I have had a flair up .. so has another person I know with it, who is still on the steriods.. so you might want to at least look into the symptoms..

Starting off with a high dose of prednisone to help with the pain/inflamation until the dmards (methotrexate/biologics) kicks in. I was on methotrexate for a year but didn't help my back at all. I am on arava now but isn't working either so I will be going on humira (biologics) later this year. Good luck!

I myself have been on methotrexate for 10 years along with prednisone. Rheumatoid Arthritis is not difficult to diagnose so I don't know why you would visit so many different doctors.

Hi, I'm 21 and was diagnosed with Rheumatoid Arthritis a couple years ago. I dealt with the pain for a few years before I was diagnosed. The odd part about my RA is that even after so many years the pain and swelling is only in one joint (my right ankle). After I was diagnosed with RA a couple years ago, I figured I should get a second opinion. I went to another Rheumatologist and he comfirm my previous Rheumatologists diagnosis.

I seem to have side effects with all the treatments my RA doctor has provided. I am allergic to methotrexate. I have problems with prednisone as well. I stopped taking all RA drugs two years ago but try to get by with over the counter meds. I recently discovered Norco 10/325 and it really helps although it is a narcotic. My question is this. How much damage could I do taking only one pill (Norco) per day. Just one pill really helps me. Thanks.

Doing research online is different than actually talking with people that have the same devistating diseases that you are faced with everyday. I want my husband to be able to crawl on the floor and play with his kids. That is why I asked his dr about a different course of meds. Before we committed to something I wanted to ask around, see what kind of effect this has on others. Spastic you are a wonderful woman, very kind and caring.

I just went back to my rheumy have had RA since Oct 09. I am on methotrexate 6 tabs on Sat. I am also on Leucovorin for mouth sores and prednisone. I am now getting more mouth sores so he prescribed a cream or tar to put on them twice daily and to go back to 5 mg of predisone from the 3 mg I had decreased down to. My question is he told me if this doesnt take care of mouth sores then my next step is injections and around $1200 a month.

Humira with methotrexate

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