I've read mixed reviews pertaining to time of med dose, most experiment find what best works for them. Some take T4 in the morning, while others take T4 at night. What's most important is consistency. Vitamins are takin a minimum of 4 hrs after hormone med.
I've taken my T4, Glipizide at the same time everyday on an empty stomach. I've recently started T3, now I take T3/T4 on an empty stomach, wait an hour take Glipzide,.