I was diagnosed with CML and given Gleevec 400 ml. After taking gleevec for 2 weeks doctor took additional blood test. My WBC dropped from 36.5 to 7.1 and all other blood counts came down to normal range. I'm wondering if gleevec could give such fast hematological response or I was possibly misdiagnosed originally. I don't and didn't have any symptoms, my spleen and liver weren't enlarged, no enlarged lymph. Should I get second opinion asap? Please, help me.
Hi Dalki,
Yes, in time your doctor will likely know for sure which type of diabetes you have. In addition to Type 1 and Type 2, there seems to be a type 1.5 ... tho' there's some thought that 1.5s are just in the early stages of Type 1. We DMers (folks with diabetes mellitis) and our docs often call that a honeymoon phase.
I hope you're feeling better now that your bloodsugar has begun to come down. Things may remain volatile for a while, so try to be patient with yourself.
I also noted the JAMA reminder/caution that food does not cause Type 1 diabetes. Type 1 diabetes is an autoimmune disease. This study and others looked at the impact of specific foods/timing of introduction in at-risk children.
Please know that Type 2 is a completely different disease than Type 1. Type 1 is autoimmune, and researchers are striving to find out what triggers (or doesn't) trigger the disease. Type 2 has completely different origins.
After two weeks on 400mlg gleevec my WBC droped from 36.5 to 7.1. My doctor told to come for additional test in two weeks. Now my WBC is 1.3 and absolute neutrophils count is 0.04. I was told to stay home on antibiotics. How long it may take for my counts to clime back to safe range. And of course, I'm off gleevec right now. Does it seem that dose of 400mlg is too high for me.
I know I am insulin dependent because I cannot take my pump off except for the rare few minutes or so without my sugar sky rocketing. Now would u still call this Type 2 Diabetes or Type 1? Hearing the words Juvenile Diabetes associated with Type 1 throws me off obviously because I was not diagnosed as a juvenile. But also the words Insulin Dependent are associated with the Type 1. So I DO fit into that category.
I have type 1 diabetes, and have had this challenging disease for 30 years. I am believing that I may be having the first signs of some nerve damage and am wondering what doctors/specialists I sure see. Right now I have a family practioner, and have had this same doctor for years....any suggestions on where to go next? I have excellent insurance (not always the case) and want to take care of this before the situation gets worse? Help.
Hi, I don't know the answer -- but since both CML and Gleevec toxicity produce anemia because of marrow suppression, maybe it's not possible to tell the difference. E.g., both would show a low reticulocyte count.
This full text paper on anemia from Gleevec https://onlinelibrary.wiley.com/doi/full/10.1002/ajh.23879 shows that other signs such as red blood cell size can vary, so that doesn't seem to help. Sorry.
You may try low carb eating, which is very helpful for blood sugar management. Type 1 grit is a group with great support and information on low carb eating for diabetes management. Look also into Dr. Richard Bernstein's Diabetes SOlutions book and Diabetes University (Utube), which has great and useful series of lectures on managing blood sugars.
A CGM (continuous glucose monitoring device) can also be very useful, though frequent finger prick testing is also ok.
Is it possible that after taking gleevec for only two weeks WBC droped from 36.7 to 7? All other blood counts are also came back to normal range. Could doctor make mistake in diagnosis of CML? Maybe I should get seg second opinion?
Congratulations!!! I too am a type 1 diabetic and my son just turned 1 last month. I had a pretty healthy pregnancy but it was very hard work. As the person above told you call your doc immediately and ask for a Rx for prenatal vitamins. Also, one of the most important nutrients for your baby is folic acid or folate. This is especially important for diabetics!!! The best sources are spinach (I know yuck...
I have had type 1 for 11 yrs now and I am 22. I just found out I am pregnant.we didn't plan to get pregnant until October.( one year of my a1c being in range). But it was sooner then expected. My a1c was 8.6 last month,and lately I have been very congested and have had sinus problems so ive been sick,and my blood sugars have been up and down.ive been trying to cut sugars and eat healthy and.not eat out.any notes that I need to take on being pregnant for the first time with diabetes?
I can't believe I've never used this resource before as I've had Type 1 since I was 11. I'm 33 now, and except for a rough first couple years, I've had great control.
One thing that made things easier for me was that since grade school I've almost always been able to ride my bike to school and later to work. I've found that the routine physical activity seems to keep my metabolism grounded.
Recommended
