Hi, I don't know the answer -- but since both CML and Gleevec toxicity produce anemia because of marrow suppression, maybe it's not possible to tell the difference. E.g., both would show a low reticulocyte count.
This full text paper on anemia from Gleevec https://onlinelibrary.wiley.com/doi/full/10.1002/ajh.23879 shows that other signs such as red blood cell size can vary, so that doesn't seem to help. Sorry.
Is it possible that after taking gleevec for only two weeks WBC droped from 36.7 to 7? All other blood counts are also came back to normal range. Could doctor make mistake in diagnosis of CML? Maybe I should get seg second opinion?
I was diagnosed with CML and given Gleevec 400 ml. After taking gleevec for 2 weeks doctor took additional blood test. My WBC dropped from 36.5 to 7.1 and all other blood counts came down to normal range. I'm wondering if gleevec could give such fast hematological response or I was possibly misdiagnosed originally. I don't and didn't have any symptoms, my spleen and liver weren't enlarged, no enlarged lymph. Should I get second opinion asap? Please, help me.
After two weeks on 400mlg gleevec my WBC droped from 36.5 to 7.1. My doctor told to come for additional test in two weeks. Now my WBC is 1.3 and absolute neutrophils count is 0.04. I was told to stay home on antibiotics. How long it may take for my counts to clime back to safe range. And of course, I'm off gleevec right now. Does it seem that dose of 400mlg is too high for me.
Am on Gleevec 400mg, now having problems with blisters on the palm. What can I do about it?
I was diagnosed last year and was immediatley put on gleevec 400mg/day.At my last consult my metabolic stats had risen,hence blood tests to determine if the gleevec is no longer working.I am still in firstphase and wonder what my options are if the gleevec is no longer an option.Amin pretty good form,just very tired and a lot of bone pain.
I have CML and was treated with Gleevec for 4 years and achieved remission. I have for the past several months been experiencing sudden onset of weakness which last for hours, to days. My blood pressure which has remained under control for several years with atenolol has been running 145/105 and higher for the past three to four months. I have a feeling of fullness in my stomach, and I have sporatic episodes of mild coughing, this occurs maybe once a week.
You might find he starts to be able to tolerate the pill. Gleevec is first choice for treating CML, and if he is doing good in every other way then encourage him that he is doing great.
I hope this helps you. I would be glad to help you with any other questions.
i get my heart checked every 2 weeks now and i am fine with the qt thing. i take the chemo pill called gleevec and have to force myself to eat so i dont get sick when i take it. how long will these withdrawel problems go on? i have xanax to take (1mg) but dont work to good. i should would appreciate any advice from any one on how to deal with these issues, family dr says its anxiety but i think its the withdrawels from the high dose of elavil.
A definite diagnosis of chronic myelogenous leukemia (CML) is made by demonstrating the existence of the Philadelphia chromosome on cytogenetic studies of the bone marrow cells (harvested by bone marrow biopsy) or by detecting the bcr-abl gene (this is the defective gene responsible for the CML) by means of a test called polymerase chain reaction or PCR. If these two tests were not done, I can't see how a diagnosis of CML can be made.
Hello Chiari world!
I was diagnosed with Chiari in May. Now two of my cousins, my mom and brother have all be diagnosed with it as well. We are joining a genetics study and are curious if any of you others out there have joined any studies. We would like to know what the Pro's and Con's were/are. We feel that since so many of us have been diagnosed in the last three months that our family may be able to help future families and our future generations by joining the study.
I was wondering if anyone knows of any free syringoma studies being conducted in southern california. Your help is greatly appreciated.
It remains unclear whether hepatitis B virus (HBV) genotype has an influence on treatment response -- as is the case for hepatitis C virus (HCV) -- due to inconsistencies across studies and failure to account for differences in race/ethnicity, according to a report in the March 2010 Journal of Hepatology.
It is well known that viral genotype has a major impact on response to interferon-based therapy for hepatitis C, but it is unclear whether this is also true for hepatitis B.
I have been recently working on some clinical studies on anxiety and I was wondering if anybody knew of any clinical support services? I have looked into a few and came across some that sound pretty good. I was wondering if anybody has ever worked with TransPerfect Trial Interactive before? I checked out their website, TrialInteractive, and they seem pretty solid but I would like to hear other people's take on it. What do you guys think? or does anybody have any other suggestions?
Hi, I'm in Knoxville Tn, and I'm looking for information on the trail studies for Hep C treatment for my mom. Does anyone have any suggestions on where to start?
Does anyone have any information on current or recent studies on this disease? I was recently diagnosed and would welcome any information. My T3 and T4 are normal but microsomal antibodies are 192(high). Thinning hair and weight gain are my concerns.
I should mention that I have CML but it has been in remission for the last two years and I am no longer taking Gleevec.
I am scheduled to be looked at by a group that kills the nerve endings in the heart that causes AF but there is an 18 month waiting period.
My question is how many times can I be cardioverted and what is the downside of having it so often?
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