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Gleevec resistance

Common Questions and Answers about Gleevec resistance

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Avatar m tn Hi, I don't know the answer -- but since both CML and Gleevec toxicity produce anemia because of marrow suppression, maybe it's not possible to tell the difference. E.g., both would show a low reticulocyte count. This full text paper on anemia from Gleevec https://onlinelibrary.wiley.com/doi/full/10.1002/ajh.23879 shows that other signs such as red blood cell size can vary, so that doesn't seem to help. Sorry.
Avatar n tn Is it possible that after taking gleevec for only two weeks WBC droped from 36.7 to 7? All other blood counts are also came back to normal range. Could doctor make mistake in diagnosis of CML? Maybe I should get seg second opinion?
Avatar n tn I was diagnosed with CML and given Gleevec 400 ml. After taking gleevec for 2 weeks doctor took additional blood test. My WBC dropped from 36.5 to 7.1 and all other blood counts came down to normal range. I'm wondering if gleevec could give such fast hematological response or I was possibly misdiagnosed originally. I don't and didn't have any symptoms, my spleen and liver weren't enlarged, no enlarged lymph. Should I get second opinion asap? Please, help me.
Avatar n tn After two weeks on 400mlg gleevec my WBC droped from 36.5 to 7.1. My doctor told to come for additional test in two weeks. Now my WBC is 1.3 and absolute neutrophils count is 0.04. I was told to stay home on antibiotics. How long it may take for my counts to clime back to safe range. And of course, I'm off gleevec right now. Does it seem that dose of 400mlg is too high for me.
Avatar n tn Am on Gleevec 400mg, now having problems with blisters on the palm. What can I do about it?
Avatar f tn I was diagnosed last year and was immediatley put on gleevec 400mg/day.At my last consult my metabolic stats had risen,hence blood tests to determine if the gleevec is no longer working.I am still in firstphase and wonder what my options are if the gleevec is no longer an option.Amin pretty good form,just very tired and a lot of bone pain.
Avatar m tn I have CML and was treated with Gleevec for 4 years and achieved remission. I have for the past several months been experiencing sudden onset of weakness which last for hours, to days. My blood pressure which has remained under control for several years with atenolol has been running 145/105 and higher for the past three to four months. I have a feeling of fullness in my stomach, and I have sporatic episodes of mild coughing, this occurs maybe once a week.
Avatar n tn You might find he starts to be able to tolerate the pill. Gleevec is first choice for treating CML, and if he is doing good in every other way then encourage him that he is doing great. I hope this helps you. I would be glad to help you with any other questions.
Avatar f tn i get my heart checked every 2 weeks now and i am fine with the qt thing. i take the chemo pill called gleevec and have to force myself to eat so i dont get sick when i take it. how long will these withdrawel problems go on? i have xanax to take (1mg) but dont work to good. i should would appreciate any advice from any one on how to deal with these issues, family dr says its anxiety but i think its the withdrawels from the high dose of elavil.
Avatar n tn You can develop resistance to a STAT-C drug however. So when someone is choosing a trial with a STAT-C drug involved, you want to choose with care - the same will apply when undergoing treatment with a STAT-C drug when they finally get to market. You want a doctor/treatment team who understands the issues and you'll want to understand them yourself so that your first attempt with a STAT-C drug is as hopefully your last.
Avatar f tn 00 Interventions for Professionals and Parents A child’s incessant screaming, spitting, and food throwing during mealtime are enough to frustrate any parent or caregiver! Continuous resistance to eating not only leads to malnourishment, but physical and intellectual developmental become additional concerns. Invariably, the underlying reason(s) for refusing to eat will differ from child to child, so the focus should be on improving or resolving the eating problem.
Avatar f tn IR or insulin resistance is a sign of type 2 diabetes or pre-diabetes. I am assuming you are referring to either the A1C or fasting blood glucose levels. The first thing of course is a change in life style. This does not mean you have to stop eating everything but to be more judicious in your eating habits. In addition, regular exercise is paramount in reducing those :numbers". Talk this over with your physician and get started on these changes.
Avatar f tn There is little doubt that the indiscriminate use of antibiotics has contributed to the emergence of bacterial resistance, both in hospitals and community settings [1]. The major force driving changes in the prevalence of resistance in the community seems to be the volume of drug use [...]" http://cid.oxfordjournals.org/content/33/Supplement_3/S170.
Avatar m tn there have been only one or two reported cas of true resistance of Chlamydia trachomatis to doxycycline and/or azithromycin. If it works out that way, I would expect your doctors to write up a scientific report for publication. I that event, I would not venture a guess about the best alternate treatment to use; that decision would rest on the lab tests to determine the best choice.n However, I still would not worry about eventual treatment success; there has never been a C.
Avatar f tn Hi! I need some ideas on different resistance training I can do at home? Trying something new so any ideas are welcome! Thanks!
Avatar f tn I have an appointment with my obgyn a week from Monday to follow up with him. Should I be tested for an immune deficiency or resistance? Any advice welcome.