gleevec research

Hi, Deanna. Yes, hyponatremia is listed as a side effect of Gleevec, though it's a rare side effect. Here is the official prescribing info, from America's FDA: https://www.drugs.com/pro/gleevec.html#s-34084-4 From that document, hyponatremia seems to occur in less than 1% of patients on Gleevec. It also might possibly be from the blood disorder itself. Are the doctors at the A&E or the GP's surgery saying it's not related? That would be odd.

Hi, I don't know the answer -- but since both CML and Gleevec toxicity produce anemia because of marrow suppression, maybe it's not possible to tell the difference. E.g., both would show a low reticulocyte count. This full text paper on anemia from Gleevec https://onlinelibrary.wiley.com/doi/full/10.1002/ajh.23879 shows that other signs such as red blood cell size can vary, so that doesn't seem to help. Sorry.

Is it possible that after taking gleevec for only two weeks WBC droped from 36.7 to 7? All other blood counts are also came back to normal range. Could doctor make mistake in diagnosis of CML? Maybe I should get seg second opinion?

I was diagnosed with CML and given Gleevec 400 ml. After taking gleevec for 2 weeks doctor took additional blood test. My WBC dropped from 36.5 to 7.1 and all other blood counts came down to normal range. I'm wondering if gleevec could give such fast hematological response or I was possibly misdiagnosed originally. I don't and didn't have any symptoms, my spleen and liver weren't enlarged, no enlarged lymph. Should I get second opinion asap? Please, help me.

After two weeks on 400mlg gleevec my WBC droped from 36.5 to 7.1. My doctor told to come for additional test in two weeks. Now my WBC is 1.3 and absolute neutrophils count is 0.04. I was told to stay home on antibiotics. How long it may take for my counts to clime back to safe range. And of course, I'm off gleevec right now. Does it seem that dose of 400mlg is too high for me.

Am on Gleevec 400mg, now having problems with blisters on the palm. What can I do about it?

I was diagnosed last year and was immediatley put on gleevec 400mg/day.At my last consult my metabolic stats had risen,hence blood tests to determine if the gleevec is no longer working.I am still in firstphase and wonder what my options are if the gleevec is no longer an option.Amin pretty good form,just very tired and a lot of bone pain.

I have CML and was treated with Gleevec for 4 years and achieved remission. I have for the past several months been experiencing sudden onset of weakness which last for hours, to days. My blood pressure which has remained under control for several years with atenolol has been running 145/105 and higher for the past three to four months. I have a feeling of fullness in my stomach, and I have sporatic episodes of mild coughing, this occurs maybe once a week.

You might find he starts to be able to tolerate the pill. Gleevec is first choice for treating CML, and if he is doing good in every other way then encourage him that he is doing great. I hope this helps you. I would be glad to help you with any other questions.

i get my heart checked every 2 weeks now and i am fine with the qt thing. i take the chemo pill called gleevec and have to force myself to eat so i dont get sick when i take it. how long will these withdrawel problems go on? i have xanax to take (1mg) but dont work to good. i should would appreciate any advice from any one on how to deal with these issues, family dr says its anxiety but i think its the withdrawels from the high dose of elavil.

s National Cancer Institute (NCI), and the Neurofibromatosis Research Program of the U.S. Army Medical Research and Material Command. "By taking a team approach and combining their unique areas of expertise, Drs. Parada and Clapp were able to shed light on a complicated disease mechanism and to develop a potential treatment," says Jane Fountain, Ph.D., a program director with NINDS. Neurofibromatosis type 1 is a genetic disease that affects about 1 in 3500 Americans.

But now, thanks to advances in genetics, we know that each cancer is unique, and research is shifting to the development of personalized medicines—designer therapies that can exterminate specific cancerous cells in a specific way, in a specific person; therapies focused like lasers. To be sure, around the turn of the millennium, significant fanfare surrounded personalized medicine, especially in the field of genetics. A lot of that is now gone.

Why is it that science and medicine research so much on synthetic chemicals and such yet all these natural items: primerose,cinnamon,aloe era,cumin,etc.... That many of us read on pregnancy website for induction for example haven't been researched the heck out of them? There's so many natural item that by now and how technology is and our advanced medicine that we don't know all about them.

Greetings doctor I am actually doing a research paper on HIV for school and with so much info online from one end of the spectrum to the other I figure I would ask a specialist directly a few questions so here it goes... 1-with testing now a days would you consider 6-8 weeks conclusive? 2-do you believe rapid tests are just as reliable as lab based? 3-do you feel oral rapid tests are just as good as blood? 4-what are the most common symptoms you see with onset of HIV?

I know somebody posted where to go to find out about the research that is going on, and what clinical trials we may be able to get into... but my brain isn't working today and I can't find the post. Somebody please give me that web site. I'd really appreciate it.

Gene therapy has potential, not to recreate lung tissue but to reduce the airway inflammation that results in emphysema, be it smoking-induced or other. Research is underway on gene therapy but the results thus far have been very disappointing. The adaptation to chronic residence at high altitude has been studied extensively. You are correct in stating that bigger lungs have nothing to do with it and that has been well known for nearly 100 years.

is there a research group one could participate with, study and analyze past, present and future findidngs/options? i have been outbreak free for years and am almost certain i recently had my first outbreak in january - and they won't stop. i think the following has provoked the virus, as well as disable the latency stage: a. i took a strong proton pump inhibitor in january for my gerd - within a week i had a broken tail bone and rash of blisters across the bottom of my back.

I should mention that I have CML but it has been in remission for the last two years and I am no longer taking Gleevec. I am scheduled to be looked at by a group that kills the nerve endings in the heart that causes AF but there is an 18 month waiting period. My question is how many times can I be cardioverted and what is the downside of having it so often?

s post - the pill is called Gleevec. It is primarily for leukemia, but it is one of the treatments my doc at MD Anderson has in his back pocket ready to give me if the time comes that I need it. Becky, I know you are facing the fact that you are out of chemo's to try. But I'm wondering about Gleevec. I don't think it is an approved ovarian cancer treatment, but right now is critical. Wonder if your doc would consier trying it. I hope the Vitamin C infusions are helping.

I need to get answers to a few questions for a research project on Thyroid Disease (prefferably from an expert or doctor)...I would be seriously grateful if these questions could be answered.. 1. What is the most common cause of Thyroidism? 2. Do you think there are enough effective treatments? 3. I understand Thyroidism is more common in women but at what age are they likely to develop it and is there any common cause for it happening at that age? 4. Do you think homeopthic remedies work? 5.

Gleevec research

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