Hi, I don't know the answer -- but since both CML and Gleevec toxicity produce anemia because of marrow suppression, maybe it's not possible to tell the difference. E.g., both would show a low reticulocyte count.
This full text paper on anemia from Gleevec https://onlinelibrary.wiley.com/doi/full/10.1002/ajh.23879 shows that other signs such as red blood cell size can vary, so that doesn't seem to help. Sorry.
Is it possible that after taking gleevec for only two weeks WBC droped from 36.7 to 7? All other blood counts are also came back to normal range. Could doctor make mistake in diagnosis of CML? Maybe I should get seg second opinion?
I was diagnosed with CML and given Gleevec 400 ml. After taking gleevec for 2 weeks doctor took additional blood test. My WBC dropped from 36.5 to 7.1 and all other blood counts came down to normal range. I'm wondering if gleevec could give such fast hematological response or I was possibly misdiagnosed originally. I don't and didn't have any symptoms, my spleen and liver weren't enlarged, no enlarged lymph. Should I get second opinion asap? Please, help me.
After two weeks on 400mlg gleevec my WBC droped from 36.5 to 7.1. My doctor told to come for additional test in two weeks. Now my WBC is 1.3 and absolute neutrophils count is 0.04. I was told to stay home on antibiotics. How long it may take for my counts to clime back to safe range. And of course, I'm off gleevec right now. Does it seem that dose of 400mlg is too high for me.
Am on Gleevec 400mg, now having problems with blisters on the palm. What can I do about it?
I was diagnosed last year and was immediatley put on gleevec 400mg/day.At my last consult my metabolic stats had risen,hence blood tests to determine if the gleevec is no longer working.I am still in firstphase and wonder what my options are if the gleevec is no longer an option.Amin pretty good form,just very tired and a lot of bone pain.
I have CML and was treated with Gleevec for 4 years and achieved remission. I have for the past several months been experiencing sudden onset of weakness which last for hours, to days. My blood pressure which has remained under control for several years with atenolol has been running 145/105 and higher for the past three to four months. I have a feeling of fullness in my stomach, and I have sporatic episodes of mild coughing, this occurs maybe once a week.
I am at the early stages of PPT (I also have postpartum anxiety) my endocrinologist put me on Tapazole 2 weeks ago. I have a mild soar throat but I believe it's merely the remnants of a cold. However, I am losing an insane amount of hair, above the average hair loss due to postpartum. Is this the combo of thyroid, meds and postpartum... I'm on tapazole 10mg daily dose. Is there something I can do? I had my blood work done on Friday and WBC was normal... does it fluctuate easily?
You may have postpartum thyroiditis (PPT). PPT is considered a "temporary"/self-resolving thyroiditis. It usually starts with a hyper phase, followed by a return to normal and then a hypo phase. However, many women only experience the hypo or the hyper, not both.
TSI (thyroid stimulating immunoglobulin) is the antibody marker for Graves'. If you have that tested, and it's elevated, you'll know you have Graves'.
I have a 7 month old son and my thyroid is way out of whack. Because of my somewhat recent pregnancy my endo seems to think that I have PPT. I have researched this and PPT goes from hyper to hypo and I thought if this was the case with my sons age I would be in the hypo stage by now....also I have no inflammation which I'm pretty sure would be required for a thyroidITIS diagnosis.
You might find he starts to be able to tolerate the pill. Gleevec is first choice for treating CML, and if he is doing good in every other way then encourage him that he is doing great.
I hope this helps you. I would be glad to help you with any other questions.
You could have Hashi's, but it's more likely you have postpartum thyroiditis. PPT is a variant of Hashi's, but many people recover from it on their own. It usually presents as an initial hyper phase, followed by a return to normal and a hypo phase, although some people only experience one of the phases.
Your FT4 is only 29% of range, which is low of the 50% target. Many of us found FT4 had to be about 50% before our symptoms were relieved.
m glad to read that I am not the only one with Thyroid issues! I am the proud mother of a new baby girl who is now 4 months old and I suffer from PPT, I had it with my first child and now I new the signs I acted fast and saw my endo. The problem is that I've been prescribed Tapazole to help me with the hyper stage until hypo sets in, and honestly, I'm really scared to take the medication. The list of side effects seem pretty severe. Is this the best process for me to take.
Has your doctor diagnosed post partum thyroiditis (PPT)?
Your TPOab is somewhat elevated, which usually indicates PPT. It's considered a variant of Hashimoto's thyroiditis, which is autoimmune thyroid disease and the most prevalent cause of hypo in the developed world.
PPT is usually a temporary condition characterized by an initial hyper phase, a brief return to normal and then a hypo phase. Hashi's, except in its very early stages, usually causes hypothyroidism.
Could any one help me to know what is my results means specially 2 things in my ppt:
(Pre). (Best)
Tlc 7.86. 8.90
Rv. 1.92. .90
Rv/tlc 26.44. 10.
I was referred to a internist right before Christmas who told me to quit nursing I should get a scan but he felt this was PPT ( Postpartum Thyroiditis ). I said no to weaning and he said I could wait 5 months at which time if I was still Hyper I would have to wean and get the uptake scan to rule out Graves. I was told the only help for me was beta blockers which I could not take while nursing or lots of rest because exerting myself would only exaggerate my symptoms.
i get my heart checked every 2 weeks now and i am fine with the qt thing. i take the chemo pill called gleevec and have to force myself to eat so i dont get sick when i take it. how long will these withdrawel problems go on? i have xanax to take (1mg) but dont work to good. i should would appreciate any advice from any one on how to deal with these issues, family dr says its anxiety but i think its the withdrawels from the high dose of elavil.
So this morning I had a ppt and I'm so nervous because I've had several miscarriages. I wonder what my chances are this time? I'm so scared, nervous, and excited all at once..
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