Hi.
Response to imatinib (gleevec) can be dramatic just like what you experienced. Myelosuppression with neutropenia (decrease in neutrophils) and thrombocytopenia (decrease in platelet count) can be a side effect of treatment. Usually, discontinuation of drug intake is advised until the blood counts increase. You should have your white blood cell count repeated after 1-2 weeks and see if it already improves. You should report to your doctor if you experience any symptoms like fever.
Hi, I don't know the answer -- but since both CML and Gleevec toxicity produce anemia because of marrow suppression, maybe it's not possible to tell the difference. E.g., both would show a low reticulocyte count.
This full text paper on anemia from Gleevec https://onlinelibrary.wiley.com/doi/full/10.1002/ajh.23879 shows that other signs such as red blood cell size can vary, so that doesn't seem to help. Sorry.
Is it possible that after taking gleevec for only two weeks WBC droped from 36.7 to 7? All other blood counts are also came back to normal range. Could doctor make mistake in diagnosis of CML? Maybe I should get seg second opinion?
I was diagnosed with CML and given Gleevec 400 ml. After taking gleevec for 2 weeks doctor took additional blood test. My WBC dropped from 36.5 to 7.1 and all other blood counts came down to normal range. I'm wondering if gleevec could give such fast hematological response or I was possibly misdiagnosed originally. I don't and didn't have any symptoms, my spleen and liver weren't enlarged, no enlarged lymph. Should I get second opinion asap? Please, help me.
Am on Gleevec 400mg, now having problems with blisters on the palm. What can I do about it?
Did your doctor prescribe it to you for this? If not, STOP right now...'experimenting' with prescription medications, which are extremely addictive can NEVER have good outcomes.
They all have reported feeling better daily - this off label approach is a God Send! Now I will finish out the 12 weeks - they will do the viral load test again at that time and then 12 weeks post treatment test again to declare me officially SVR!!!
NO HORRIBLE INTERFERON OR RIBAVARIN THIS TIME FOR ME!!
I was diagnosed last year and was immediatley put on gleevec 400mg/day.At my last consult my metabolic stats had risen,hence blood tests to determine if the gleevec is no longer working.I am still in firstphase and wonder what my options are if the gleevec is no longer an option.Amin pretty good form,just very tired and a lot of bone pain.
I have CML and was treated with Gleevec for 4 years and achieved remission. I have for the past several months been experiencing sudden onset of weakness which last for hours, to days. My blood pressure which has remained under control for several years with atenolol has been running 145/105 and higher for the past three to four months. I have a feeling of fullness in my stomach, and I have sporatic episodes of mild coughing, this occurs maybe once a week.
Thank you! I will definitely suggest that. His doctor just took him off the Gleevec for a week to see if it is indeed the Gleevec that is making him sick. I guess there are 2 more medications that do the same thing that he might be able to try if needed. I can't imagine that any of these medications come with no side effects, so your suggestion is very much appreciated!!
After reviewing the medications I was already taking (to avoid any conflicts) she recommended Lamotrigine for my intense anxiety. I am VERY familiar with off-label drug uses, but I can find no information re: the use of this drug for my situation. It is a drug used for bi-polar disorder and seizures. I thought that Atavan would be the drug of choice, and after reading more about Lamotrigine, I have become actually quite shocked about this recommendation.
i get my heart checked every 2 weeks now and i am fine with the qt thing. i take the chemo pill called gleevec and have to force myself to eat so i dont get sick when i take it. how long will these withdrawel problems go on? i have xanax to take (1mg) but dont work to good. i should would appreciate any advice from any one on how to deal with these issues, family dr says its anxiety but i think its the withdrawels from the high dose of elavil.
Are there any off label drugs which can be useful for herpes? I have read therapy with Tagamet and zinc may have some benefit but I cant find any good information on that to show my doctor. Also what about globulin or interfereon injections ? Are there other immune modulating drugs or treatments that can boost my t-cells against this virus to keep it down?
Is there a type of doctor who may know more about this than my PCP ? Have you ever encountered this before in a healthy person?
Grammy, I remember you saying your doc was prescribing off label for all his patients. Do you have any idea what reasons he is giving to insurance....as in key words or arguments he has to support the off label. Hope that makes sense. So tired and it's been a frustrating day.
Again, so very happy for your success! Can you spell CURED?
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