After two weeks on 400mlg gleevec my WBC droped from 36.5 to 7.1. My doctor told to come for additional test in two weeks. Now my WBC is 1.3 and absolute neutrophils count is 0.04. I was told to stay home on antibiotics. How long it may take for my counts to clime back to safe range. And of course, I'm off gleevec right now. Does it seem that dose of 400mlg is too high for me.
Hi, I don't know the answer -- but since both CML and Gleevec toxicity produce anemia because of marrow suppression, maybe it's not possible to tell the difference. E.g., both would show a low reticulocyte count.
This full text paper on anemia from Gleevec https://onlinelibrary.wiley.com/doi/full/10.1002/ajh.23879 shows that other signs such as red blood cell size can vary, so that doesn't seem to help. Sorry.
Is it possible that after taking gleevec for only two weeks WBC droped from 36.7 to 7? All other blood counts are also came back to normal range. Could doctor make mistake in diagnosis of CML? Maybe I should get seg second opinion?
I was diagnosed with CML and given Gleevec 400 ml. After taking gleevec for 2 weeks doctor took additional blood test. My WBC dropped from 36.5 to 7.1 and all other blood counts came down to normal range. I'm wondering if gleevec could give such fast hematological response or I was possibly misdiagnosed originally. I don't and didn't have any symptoms, my spleen and liver weren't enlarged, no enlarged lymph. Should I get second opinion asap? Please, help me.
Am on Gleevec 400mg, now having problems with blisters on the palm. What can I do about it?
I was diagnosed last year and was immediatley put on gleevec 400mg/day.At my last consult my metabolic stats had risen,hence blood tests to determine if the gleevec is no longer working.I am still in firstphase and wonder what my options are if the gleevec is no longer an option.Amin pretty good form,just very tired and a lot of bone pain.
I have CML and was treated with Gleevec for 4 years and achieved remission. I have for the past several months been experiencing sudden onset of weakness which last for hours, to days. My blood pressure which has remained under control for several years with atenolol has been running 145/105 and higher for the past three to four months. I have a feeling of fullness in my stomach, and I have sporatic episodes of mild coughing, this occurs maybe once a week.
You might find he starts to be able to tolerate the pill. Gleevec is first choice for treating CML, and if he is doing good in every other way then encourage him that he is doing great.
I hope this helps you. I would be glad to help you with any other questions.
I had a blood test yesterday and results show a WBC of 2.9 and also low neutrophils of .60 (meaning I have moderate neutropenia). All other values are within range.
I had a blood test done a year ago and everything was good then (WBC of 5.6).
I don't have a fever or additional symptoms and don't think I have a virus.
I have as few questions:
1. Could this be a normal swing in my WBC, is it fairly common for healthy people to drop low and bounce back up?
2.
Are you currently on any medication like imatinib? The neutropenia can be due to your current medication. You can ask your hematologist for G-CSF injection if you have persistent neutropenia. Patients with CML are immunocompromised and can easily acquire infections. Neutropenia also puts a patient in an immunocompromised state.
For now, it is very important to prevent acquiring any infection. You should avoid crowded places and persons with ongoing infection.
Good luck.
i get my heart checked every 2 weeks now and i am fine with the qt thing. i take the chemo pill called gleevec and have to force myself to eat so i dont get sick when i take it. how long will these withdrawel problems go on? i have xanax to take (1mg) but dont work to good. i should would appreciate any advice from any one on how to deal with these issues, family dr says its anxiety but i think its the withdrawels from the high dose of elavil.
re considering an interferon dose reduction?? If neutropenia, the following applies to Inf/Riba, not the PIs.
Neutropenia frequently complicates IFN-based antiviral therapy for hepatitis C [14]. The relationship between neutropenia and infectious complications in this instance is not well described.
Hello all, I'm not sure if everyone is familiar with my story but I have neutropenia and graves disease. I need to get my wisdom tooth extracted because I have avoided it long enough. When I first tried to get my wisdom pulled the dental surgeon realized that my wisdom tooth was in my nerve and that i would suffer damage if pulled. I was told to prolong it as much as I could however, I get horrible migraines (I've suffered from migraines since 13) and I need my tooth taken out.
My 17 month old son just had 2nd blood test come back with low neutrophils and high lymphocytes. The doctor said something about neutropenia? Should i be worried or is this just sign of a virus?
Normal banded neutrophil count is 1,500 cells per microliter. A count between 500-1000, is a grade 3 risk of neutropenia, or low neutrophil count, with risk for infection.
Actually on the first day of fever and even for a day or two, initially when there is an infection, there is slight neutropenia. Then the body fights the infection and the neutrophils rise and by day five of fever most blood pictures will show increased neutrophil count.
Did I develop neutropenia from the Graves disease and how do I stop the neutropenia from getting worse? Also, what are some things that I should avoid as a result of my neutropenia? In addition, my heart rate ranges from 120-140 and I feel very tired and confused. Are these feelings a result of my heart rate? Thank you in advance.
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