Hi, I don't know the answer -- but since both CML and Gleevec toxicity produce anemia because of marrow suppression, maybe it's not possible to tell the difference. E.g., both would show a low reticulocyte count.
This full text paper on anemia from Gleevec https://onlinelibrary.wiley.com/doi/full/10.1002/ajh.23879 shows that other signs such as red blood cell size can vary, so that doesn't seem to help. Sorry.
Is it possible that after taking gleevec for only two weeks WBC droped from 36.7 to 7? All other blood counts are also came back to normal range. Could doctor make mistake in diagnosis of CML? Maybe I should get seg second opinion?
I was diagnosed with CML and given Gleevec 400 ml. After taking gleevec for 2 weeks doctor took additional blood test. My WBC dropped from 36.5 to 7.1 and all other blood counts came down to normal range. I'm wondering if gleevec could give such fast hematological response or I was possibly misdiagnosed originally. I don't and didn't have any symptoms, my spleen and liver weren't enlarged, no enlarged lymph. Should I get second opinion asap? Please, help me.
After two weeks on 400mlg gleevec my WBC droped from 36.5 to 7.1. My doctor told to come for additional test in two weeks. Now my WBC is 1.3 and absolute neutrophils count is 0.04. I was told to stay home on antibiotics. How long it may take for my counts to clime back to safe range. And of course, I'm off gleevec right now. Does it seem that dose of 400mlg is too high for me.
Am on Gleevec 400mg, now having problems with blisters on the palm. What can I do about it?
I was diagnosed last year and was immediatley put on gleevec 400mg/day.At my last consult my metabolic stats had risen,hence blood tests to determine if the gleevec is no longer working.I am still in firstphase and wonder what my options are if the gleevec is no longer an option.Amin pretty good form,just very tired and a lot of bone pain.
I have CML and was treated with Gleevec for 4 years and achieved remission. I have for the past several months been experiencing sudden onset of weakness which last for hours, to days. My blood pressure which has remained under control for several years with atenolol has been running 145/105 and higher for the past three to four months. I have a feeling of fullness in my stomach, and I have sporatic episodes of mild coughing, this occurs maybe once a week.
I recently worked with an epoxy that I had thought was an MSDS Health rating 2, which means:
"Intense or continued exposure could cause temporary incapacitation or possible residual injury unless prompt medical attention is given."
The warnings on the package suggest to avoid eye/skin contact, avoid breathing vapors and to work in "adequate ventilation" (note that no one ever explains what this means).
You might find he starts to be able to tolerate the pill. Gleevec is first choice for treating CML, and if he is doing good in every other way then encourage him that he is doing great.
I hope this helps you. I would be glad to help you with any other questions.
http://www.atsdr.cdc.gov/toxfaqs/tf.asp?id=255&tid=47
~ Dr. Parks
This answer is not intended as and does not substitute for medical advice. The information presented in this posting is for patients’ education only. As always, I encourage you to see your personal physician for further evaluation of your individual case.
Hi I am not a doctor but I would think that there would be an MSDS sheet that would explain the dangers. You already know that everything you we eat breathe and put on the body has to be processed by the liver. I will try to find something. and come back.
i get my heart checked every 2 weeks now and i am fine with the qt thing. i take the chemo pill called gleevec and have to force myself to eat so i dont get sick when i take it. how long will these withdrawel problems go on? i have xanax to take (1mg) but dont work to good. i should would appreciate any advice from any one on how to deal with these issues, family dr says its anxiety but i think its the withdrawels from the high dose of elavil.
They keep on telling me that all i was exposed to was general purpose oil, used in the vacuum pump of the GCMS. There was no extraction from the GCMS instrument. I looked up the MSDS for that chemical but my symtoms are not consitent with there findings.
I sent off a hair sample to the US for mineral analysis. It stated that i had high levels of tin. I know inorganic tin is more or less harmless, or is it?, but can organotin cause these type of symtoms?.
I looked up the MSDS (Material Safety Data Sheet) for Jeltrate Dustless Alginate Impression Material and under emergencies, it states that ingestion (swallowing it) that "Material is probably not harmful is swallowed" and "Low order of toxicity is expected when material is ingested."
If you want to, you may want to schedule your mom for a consultation with a GI (gastrointestinal) specialist to see what they may have to say about it.
Hope that helps.
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