Hi, I don't know the answer -- but since both CML and Gleevec toxicity produce anemia because of marrow suppression, maybe it's not possible to tell the difference. E.g., both would show a low reticulocyte count.
This full text paper on anemia from Gleevec https://onlinelibrary.wiley.com/doi/full/10.1002/ajh.23879 shows that other signs such as red blood cell size can vary, so that doesn't seem to help. Sorry.
Is it possible that after taking gleevec for only two weeks WBC droped from 36.7 to 7? All other blood counts are also came back to normal range. Could doctor make mistake in diagnosis of CML? Maybe I should get seg second opinion?
I was diagnosed with CML and given Gleevec 400 ml. After taking gleevec for 2 weeks doctor took additional blood test. My WBC dropped from 36.5 to 7.1 and all other blood counts came down to normal range. I'm wondering if gleevec could give such fast hematological response or I was possibly misdiagnosed originally. I don't and didn't have any symptoms, my spleen and liver weren't enlarged, no enlarged lymph. Should I get second opinion asap? Please, help me.
After two weeks on 400mlg gleevec my WBC droped from 36.5 to 7.1. My doctor told to come for additional test in two weeks. Now my WBC is 1.3 and absolute neutrophils count is 0.04. I was told to stay home on antibiotics. How long it may take for my counts to clime back to safe range. And of course, I'm off gleevec right now. Does it seem that dose of 400mlg is too high for me.
Am on Gleevec 400mg, now having problems with blisters on the palm. What can I do about it?
I was diagnosed last year and was immediatley put on gleevec 400mg/day.At my last consult my metabolic stats had risen,hence blood tests to determine if the gleevec is no longer working.I am still in firstphase and wonder what my options are if the gleevec is no longer an option.Amin pretty good form,just very tired and a lot of bone pain.
I have CML and was treated with Gleevec for 4 years and achieved remission. I have for the past several months been experiencing sudden onset of weakness which last for hours, to days. My blood pressure which has remained under control for several years with atenolol has been running 145/105 and higher for the past three to four months. I have a feeling of fullness in my stomach, and I have sporatic episodes of mild coughing, this occurs maybe once a week.
You might find he starts to be able to tolerate the pill. Gleevec is first choice for treating CML, and if he is doing good in every other way then encourage him that he is doing great.
I hope this helps you. I would be glad to help you with any other questions.
2 months ago I got a cold and my doctor put me immunosuppression. I passed the test for HIV after 12 weeks of risk, the result is negative, can we consider the final result?
immunosuppression, neoplasia (cancers), anemia, immune-mediated diseases, and gastroenteritis,
1. Immunosuppression: There is an increased susceptibility to bacterial, fungal, protozoal, and other viral infections.
2. Neoplasia: Most commonly the mediastinal, multicentric, or spinal forms of lymphoma. However it is also found less commonly in renal and other cancers.
3.
t know what the doctor meant by long time, and desperately looking for some answers. Any history of patients given this diagnosis considering stopping immunosuppression? Quality of life? I am pretty sure the question of re-transplantation is not an option based on current health. Thanks for your response.
if a liver biopsy shows that this is recurrent HCV and not rejection and antiviral teatment is not to be started, then lowering the immunosuppression somewhat is the way to go. if interferon is to be used to treat the HCV then the immunosuppression cannot be too low or rejection will be precipitated.
i get my heart checked every 2 weeks now and i am fine with the qt thing. i take the chemo pill called gleevec and have to force myself to eat so i dont get sick when i take it. how long will these withdrawel problems go on? i have xanax to take (1mg) but dont work to good. i should would appreciate any advice from any one on how to deal with these issues, family dr says its anxiety but i think its the withdrawels from the high dose of elavil.
1.) makes me more contagious to others, because maybe my body isn't as good now at fighting the virus? If so, would daily antivirals negate this additional risk? 2.) makes my antibodies (I've had them for 10 years) less effective and therefore makes autoinnoculation possible- that I could spread my own virus to other parts of my body or that I would be less protected against getting hsv 1 in a new place or hsv 2 3.) am I at higher risk of contracting stds in general?
Hi,
Ive had addisons for like 12 years, and was never really told by endocrinologists that the steroids can cause immunosuppression. I've only learned this recently. Has anyone found that they have inaccurate bloods tests when testing for various diseases that require an antibody response? Has anyone found they have a weakened immune system?
4th week testing is useless.
Ok, i have had two sexual partners in the previous 12 months, regular unprotected sex with a girl, but i also had fully protected sex with a transexual prostitute around 10 weeks ago (last sexual encounter to date).
I had some minor gential discomfort which seemed to pass between having sex with the girl and the prostitute (which was a very short time frame).
The condom spilt with the prostitute whilst i was penetrating, i stopped immeadiatly.
however, there is no documented increased cancer risk specifically with the use of long-term mycophenolate use. the less immunosuppression one takes over time, the better however.
you are confusing autoimmune diseases and immunosuppression (being immunocompromised). The latter is where there is a theoretical possibility of delayed seroconversion. That would include people on chemo, people with advanced, terminal cancers, people taking anti-rejection meds after an organ transplant, heavy IV drug users.
It's where a person's immune system is actually compromised, and not working properly.
, ect, the above study (and others available through common google searches) clearly demonstrate, that is potentially dangerous advise to someone considering immunosuppression choices. BTW- dead, killed or no virus can not cause disease (relapse) hence the prevalence of 'killed' over 'attenuated' (weakened) virus for vaccinations.
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