Hi there.
It is important to be empathic, and let your brother know that you are always there for him. However, you should not overdo this, since this might lower your brother's self esteem further and cause him to have self-pity. CML is a manageable disease given the appropriate medications. Not all CML's are candidate for Gleevec. Only those who tested positive for the philadelphia chromosome or the bcr-abl gene would be candidates to receive gleevec.
Hi, I don't know the answer -- but since both CML and Gleevec toxicity produce anemia because of marrow suppression, maybe it's not possible to tell the difference. E.g., both would show a low reticulocyte count.
This full text paper on anemia from Gleevec https://onlinelibrary.wiley.com/doi/full/10.1002/ajh.23879 shows that other signs such as red blood cell size can vary, so that doesn't seem to help. Sorry.
I was diagnosed with CML and given Gleevec 400 ml. After taking gleevec for 2 weeks doctor took additional blood test. My WBC dropped from 36.5 to 7.1 and all other blood counts came down to normal range. I'm wondering if gleevec could give such fast hematological response or I was possibly misdiagnosed originally. I don't and didn't have any symptoms, my spleen and liver weren't enlarged, no enlarged lymph. Should I get second opinion asap? Please, help me.
Hi.
Response to imatinib (gleevec) can be dramatic just like what you experienced. Myelosuppression with neutropenia (decrease in neutrophils) and thrombocytopenia (decrease in platelet count) can be a side effect of treatment. Usually, discontinuation of drug intake is advised until the blood counts increase. You should have your white blood cell count repeated after 1-2 weeks and see if it already improves. You should report to your doctor if you experience any symptoms like fever.
Am on Gleevec 400mg, now having problems with blisters on the palm. What can I do about it?
I was diagnosed last year and was immediatley put on gleevec 400mg/day.At my last consult my metabolic stats had risen,hence blood tests to determine if the gleevec is no longer working.I am still in firstphase and wonder what my options are if the gleevec is no longer an option.Amin pretty good form,just very tired and a lot of bone pain.
I have CML and was treated with Gleevec for 4 years and achieved remission. I have for the past several months been experiencing sudden onset of weakness which last for hours, to days. My blood pressure which has remained under control for several years with atenolol has been running 145/105 and higher for the past three to four months. I have a feeling of fullness in my stomach, and I have sporatic episodes of mild coughing, this occurs maybe once a week.
i was diagnosed with cml in march of 2009 and was also taking 150mg of elavil at bedtime to control migraines for like 10 years. then this past dec. a heart test showed i had prolonged qt of the heart so i was stopped 'cold turkey' by a dr and its been down hill ever since. i have had the shakes, loss of appetite and constant nausea. i wake up evey morning shaky really bad.
So are you saying that even without other symptoms for years now, that this could be lymphoma??????
Interesting. That is the first I've heard of it, but maybe it's only a test for specific types of Lymphoma and not all Lymphomas. Perhaps someone else here will chime in who has had experience with this. Thanks for sharing.
I found a new ENT who took the time to review my previous results. He agreed to send me for a biopsy per my request however the hospital for whatever reason wanted updated CT scans before I had the biopsy done. So the other day I went for another CT scan and today I went in to review the results.
It still says that the lymph node in question is still 1 cm which I was told is a good sign.
ABVD (Doxorubicin, Bleomycin, Vinblastine, Dacarbazine) regimen is a common combination used for Hodgkin’s lymphoma. This is given every 2 weeks for about 12 sessions or 6 cycles (1 cycle = 2 sessions), depending on your response to treatment.
If you are highly considering having a child someday, I suggest you tell this to your doctor since one of the side effects of chemotherapy is infertility. Other side effects include hair loss, body weakness, nausea and vomiting, and allergic reaction.
The only thing I can think of would be nerve ending damage which can happen while having treatment. Ask your doctor about that. I had it and it is not nice.
Recommended
