Hi there.
It is important to be empathic, and let your brother know that you are always there for him. However, you should not overdo this, since this might lower your brother's self esteem further and cause him to have self-pity. CML is a manageable disease given the appropriate medications. Not all CML's are candidate for Gleevec. Only those who tested positive for the philadelphia chromosome or the bcr-abl gene would be candidates to receive gleevec.
Hi, I don't know the answer -- but since both CML and Gleevec toxicity produce anemia because of marrow suppression, maybe it's not possible to tell the difference. E.g., both would show a low reticulocyte count.
This full text paper on anemia from Gleevec https://onlinelibrary.wiley.com/doi/full/10.1002/ajh.23879 shows that other signs such as red blood cell size can vary, so that doesn't seem to help. Sorry.
I was diagnosed with CML and given Gleevec 400 ml. After taking gleevec for 2 weeks doctor took additional blood test. My WBC dropped from 36.5 to 7.1 and all other blood counts came down to normal range. I'm wondering if gleevec could give such fast hematological response or I was possibly misdiagnosed originally. I don't and didn't have any symptoms, my spleen and liver weren't enlarged, no enlarged lymph. Should I get second opinion asap? Please, help me.
For a PET scan, they give you a tracer of some sort to make a tumor show up. I do not think the benign tumors take up the tracer like the malignant ones, hence why the PET scan works (or so how I think it works).
The doctor will have to tell you if the lesion in her brain is related or not - but it may or may not be cancer. I hope not.
The vast majority of headaches are not brain tumors. Brain tumors are actually very rare, and headaches can be caused so many different things. Headaches are just one of many symptoms of brain tumors (and they are rarely the sole presenting symptom). Also, in 3-4 years you would have most likely developed other symptoms (or be dead by now) if it were a brain tumor. That said, it might be appropriate to have an mri to help figure out what is going on.
Hi.
Response to imatinib (gleevec) can be dramatic just like what you experienced. Myelosuppression with neutropenia (decrease in neutrophils) and thrombocytopenia (decrease in platelet count) can be a side effect of treatment. Usually, discontinuation of drug intake is advised until the blood counts increase. You should have your white blood cell count repeated after 1-2 weeks and see if it already improves. You should report to your doctor if you experience any symptoms like fever.
Am on Gleevec 400mg, now having problems with blisters on the palm. What can I do about it?
I was diagnosed last year and was immediatley put on gleevec 400mg/day.At my last consult my metabolic stats had risen,hence blood tests to determine if the gleevec is no longer working.I am still in firstphase and wonder what my options are if the gleevec is no longer an option.Amin pretty good form,just very tired and a lot of bone pain.
I have CML and was treated with Gleevec for 4 years and achieved remission. I have for the past several months been experiencing sudden onset of weakness which last for hours, to days. My blood pressure which has remained under control for several years with atenolol has been running 145/105 and higher for the past three to four months. I have a feeling of fullness in my stomach, and I have sporatic episodes of mild coughing, this occurs maybe once a week.
Hello. I was diagnosed with a pituitary tumor about 6 months ago...and for some reason they have not removed the tumor. It has been causing me to have very bad headaches and other pain in my body. I have also developed tumors in my arm(not sure if it is related) I have also been told that my thyroid has shut down on me. They have put me on synthroid and have been increasing the dose all the time, but nothing seems to be working.
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