Hi there.
It is important to be empathic, and let your brother know that you are always there for him. However, you should not overdo this, since this might lower your brother's self esteem further and cause him to have self-pity. CML is a manageable disease given the appropriate medications. Not all CML's are candidate for Gleevec. Only those who tested positive for the philadelphia chromosome or the bcr-abl gene would be candidates to receive gleevec.
Hi, I don't know the answer -- but since both CML and Gleevec toxicity produce anemia because of marrow suppression, maybe it's not possible to tell the difference. E.g., both would show a low reticulocyte count.
This full text paper on anemia from Gleevec https://onlinelibrary.wiley.com/doi/full/10.1002/ajh.23879 shows that other signs such as red blood cell size can vary, so that doesn't seem to help. Sorry.
I was diagnosed with CML and given Gleevec 400 ml. After taking gleevec for 2 weeks doctor took additional blood test. My WBC dropped from 36.5 to 7.1 and all other blood counts came down to normal range. I'm wondering if gleevec could give such fast hematological response or I was possibly misdiagnosed originally. I don't and didn't have any symptoms, my spleen and liver weren't enlarged, no enlarged lymph. Should I get second opinion asap? Please, help me.
Hi.
Response to imatinib (gleevec) can be dramatic just like what you experienced. Myelosuppression with neutropenia (decrease in neutrophils) and thrombocytopenia (decrease in platelet count) can be a side effect of treatment. Usually, discontinuation of drug intake is advised until the blood counts increase. You should have your white blood cell count repeated after 1-2 weeks and see if it already improves. You should report to your doctor if you experience any symptoms like fever.
Am on Gleevec 400mg, now having problems with blisters on the palm. What can I do about it?
I was diagnosed last year and was immediatley put on gleevec 400mg/day.At my last consult my metabolic stats had risen,hence blood tests to determine if the gleevec is no longer working.I am still in firstphase and wonder what my options are if the gleevec is no longer an option.Amin pretty good form,just very tired and a lot of bone pain.
I heard recently on a tv show that there are blood tests that will confirm whether you are likely to get leukemia. Both my parents died of leukemia in 2009. My father had AML, my mother had CML. Can anyone give me some information I am seeking?
I was asked to have a blood test taken in 2009, and my doctor then said there was something they would watch, but then she retired, and I have no idea what she was talking about.
Any info would be a benefit! Thank you!
ALSO as women age, the incidence of twins increases. As for AML. there DOES appear to be a hereditary link. First degree relatives (such as sisters and brothers) of AML patients have a three-fold increased risk for developing the disease.
I am very sorry to hear your story, and can completely understand your concerns. If you want that girl badly enough, it is probably worth the risk. But of course you must think in terms of what is best for the whole family.
Good luck!
I have CML and was treated with Gleevec for 4 years and achieved remission. I have for the past several months been experiencing sudden onset of weakness which last for hours, to days. My blood pressure which has remained under control for several years with atenolol has been running 145/105 and higher for the past three to four months. I have a feeling of fullness in my stomach, and I have sporatic episodes of mild coughing, this occurs maybe once a week.
hello,,,,, my2D echocardiography report says ......AML thickning with 12mm MVP without mitral regurge, CAN U EXPLAIN THIS TO ME PLEASE?
In 2009 i was diagnose Blood cancer(AML) and in 2010 i got bone marrow transplant(BMT) for it, right now my report related to Serum Bilirubin is normal but from there till now my OT/PT never stable some time it comes with in range of 45 also. i'm non alcoholic, non smoker, kindly advice me what precaution in should i take to keep my OT/PT control either in diet or else any. waiting for ur reply. Thank you.
After taking 3 paracetamol, fever gone. Last few days my urine colour is looks black. Today i went for another cbc. It was wbc 3.3 and plateletes 160000. I am afraid of Aml or cll. Please tell me about it.
Hi there and welcome to the forum. I'm sorry to hear about your mother-in-law. It is strange that just three weeks ago the blood tests were fine, but possibly she had a different kind of blood test? This is something I would ask the doctor about.
I have never heard of "acute leukemia myloma", however you might look up Acute Myeloid Leukemia also known as AML. There is also a disease called Multiple Myeloma, which is completely different than AML.
Hi Klemery,
I was diagnosed with MDS which, despite chemo, was progressing to AML. I too started getting, twitching, tingling nerve pain, slight muscle wasting and weakness.
Long story short. Turns out I have a metabolic disease which prevents me utilizing copper and other metals properly. I supposedly, never had MDS in the first place!
i was diagnosed with cml in march of 2009 and was also taking 150mg of elavil at bedtime to control migraines for like 10 years. then this past dec. a heart test showed i had prolonged qt of the heart so i was stopped 'cold turkey' by a dr and its been down hill ever since. i have had the shakes, loss of appetite and constant nausea. i wake up evey morning shaky really bad.
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