Hi, I don't know the answer -- but since both CML and Gleevec toxicity produce anemia because of marrow suppression, maybe it's not possible to tell the difference. E.g., both would show a low reticulocyte count.
This full text paper on anemia from Gleevec https://onlinelibrary.wiley.com/doi/full/10.1002/ajh.23879 shows that other signs such as red blood cell size can vary, so that doesn't seem to help. Sorry.
I was diagnosed with CML and given Gleevec 400 ml. After taking gleevec for 2 weeks doctor took additional blood test. My WBC dropped from 36.5 to 7.1 and all other blood counts came down to normal range. I'm wondering if gleevec could give such fast hematological response or I was possibly misdiagnosed originally. I don't and didn't have any symptoms, my spleen and liver weren't enlarged, no enlarged lymph. Should I get second opinion asap? Please, help me.
t want to see me, that fever was not from gleevec, and that I needed to monitor myself by myself by simply taken ibuprofen. This is what I did all last week and only this Monday he did a blood work.
For now, what can I do to help my body to build my immune system back? Any vitamins? I'll appriciate any advice.
I was diagnosed last year and was immediatley put on gleevec 400mg/day.At my last consult my metabolic stats had risen,hence blood tests to determine if the gleevec is no longer working.I am still in firstphase and wonder what my options are if the gleevec is no longer an option.Amin pretty good form,just very tired and a lot of bone pain.
I have CML and was treated with Gleevec for 4 years and achieved remission. I have for the past several months been experiencing sudden onset of weakness which last for hours, to days. My blood pressure which has remained under control for several years with atenolol has been running 145/105 and higher for the past three to four months. I have a feeling of fullness in my stomach, and I have sporatic episodes of mild coughing, this occurs maybe once a week.
Went back in January, had slight swelling down the right side of my neck to the colarbone. Had CBC, Thyroid, and Complete metabolic test.. all were normal.. went back 1st of Febuary more swelling and pain still there, more blood work all normal, and a Non specific ultrasound of the neck.. Surgeon did a physical exam and looked at blood work.. Said he didnt think it was anything.. Now 10 days later started having a slight fever at night and some sweating..
i get my heart checked every 2 weeks now and i am fine with the qt thing. i take the chemo pill called gleevec and have to force myself to eat so i dont get sick when i take it. how long will these withdrawel problems go on? i have xanax to take (1mg) but dont work to good. i should would appreciate any advice from any one on how to deal with these issues, family dr says its anxiety but i think its the withdrawels from the high dose of elavil.
I should mention that I have CML but it has been in remission for the last two years and I am no longer taking Gleevec.
I am scheduled to be looked at by a group that kills the nerve endings in the heart that causes AF but there is an 18 month waiting period.
My question is how many times can I be cardioverted and what is the downside of having it so often?
I was diagnosed w/CMML in 2009 and did 6mos of Vidaza. Monocyte levels keep rising and are now at 28%. 54 yr old male. My drs. just keep telling me to watch and wait, but I don't feel comfortable doing that, especially since I am fighting a recurrent staph infection that keeps returning every month.
She then went to Mayo and the doctor there told her she did not have Leukemia based on her blood work there, but she had been overdosed on Hydrea during the summer to the point her wbc was 3 and was only recovered to 11 by the time of her appt in Sept. Now her wbc is 58 and her hometown doctor is putting her back on Hydrea. Her family is concerned she is going to take a serious chemo drug when there is still a question of what she has. Could it be an infection that isn't showing up?
Stella has provided the tests you need - I'd also recommend cortisol tests to see if your adrenal gland is functioning okay - maybe you'd do better on a T3/T4 med like Armour? I'd also have your Vitamin D levels checked. You'd be surprised how D deficiency can affect your body. Google Vitamin D deficiency and see what you find. I take 4,000 IU's a day and mine still stays low at 30 in a range of 20-80. NOt sure why I cannot get it up!
Impressions: Single focus of FLAIR hyperintensity is seen within the mid left frontal lobe.
THYROID ULTRASOUND 2020:
Impressions: Mild thyromegaly with small benign right lower lobe nodule (probably colloid) and tiny benign left
upper lobe cyst. No suspicious mass to warrant biopsy.
SPINE X-RAYS:
Impressions: Reversal of cervical curvature.
*Mild dextroscoliosis.
*Minimal Scoliosis
SPINE MRI: IMPRESSION:
Mild degenerative disc desiccation with bulging annulus at C3-C4 through C6-C7 level.
I have had my thyroid tested before I was diagnosed with lupus. My thyroid function is fine.
T4 is converted to “T3” in the thyroid, liver, brain and other tissues. T3 is the active form, 200 times stronger than T4.
The importance of TSH
TSH, made by the pituitary gland in the brain, stands for thyroid stimulating hormone. If your thyroid is sluggish, your pituitary produces more TSH, a kind of kick in the pants for the thyroid. The TSH blood test is the most useful test for thyroid function.
What causes a sluggish thyroid?
A common cause is autoimmune.
Keep in mind the higher the number the more under active your thyroid is(hypo)
What often happens(not always ) early in tx. ..the interferon ramps up the thyroid and puts in into overdrive and then can somewhat damage it and as treatment goes on or after tx. the thyroid gets underactive( hypo)..in other words not working so good and the numbers will rise.
The bad news if this happens ..it is usually the way it stays ..
This will result in a need for a greater doses of thyroid hormone, and a greater possibility of side effects including heart palpitations and anxiety.
Use this herb for thyroid if you have autoimmune thyroid disease, or if you are noticeably fatigued, and sensitive to stress.
How to take: Withania can be taken as a fluid extract or a tablet. Because the herb is so gentle, a relatively large dose must be used to see an effect on thyroid function. Consult your Naturopath.
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