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Gleevec and gvhd

Common Questions and Answers about Gleevec and gvhd

gleevec

Avatar m tn Hi, I don't know the answer -- but since both CML and Gleevec toxicity produce anemia because of marrow suppression, maybe it's not possible to tell the difference. E.g., both would show a low reticulocyte count. This full text paper on anemia from Gleevec https://onlinelibrary.wiley.com/doi/full/10.1002/ajh.23879 shows that other signs such as red blood cell size can vary, so that doesn't seem to help. Sorry.
Avatar n tn I was diagnosed with CML in May with WBC at 222 and an enlarged spleen. Currently on Gleevec 400mg and the last FBC shows WBC at 2.1 . Still maintaining current dose of 400mg.Apart from some annoying blisters on my palm, other side effects rather acceptable.
Avatar n tn I was diagnosed with CML and given Gleevec 400 ml. After taking gleevec for 2 weeks doctor took additional blood test. My WBC dropped from 36.5 to 7.1 and all other blood counts came down to normal range. I'm wondering if gleevec could give such fast hematological response or I was possibly misdiagnosed originally. I don't and didn't have any symptoms, my spleen and liver weren't enlarged, no enlarged lymph. Should I get second opinion asap? Please, help me.
Avatar n tn t want to see me, that fever was not from gleevec, and that I needed to monitor myself by myself by simply taken ibuprofen. This is what I did all last week and only this Monday he did a blood work. For now, what can I do to help my body to build my immune system back? Any vitamins? I'll appriciate any advice.
Avatar f tn I was diagnosed last year and was immediatley put on gleevec 400mg/day.At my last consult my metabolic stats had risen,hence blood tests to determine if the gleevec is no longer working.I am still in firstphase and wonder what my options are if the gleevec is no longer an option.Amin pretty good form,just very tired and a lot of bone pain.
Avatar m tn I have CML and was treated with Gleevec for 4 years and achieved remission. I have for the past several months been experiencing sudden onset of weakness which last for hours, to days. My blood pressure which has remained under control for several years with atenolol has been running 145/105 and higher for the past three to four months. I have a feeling of fullness in my stomach, and I have sporatic episodes of mild coughing, this occurs maybe once a week.
Avatar n tn You might find he starts to be able to tolerate the pill. Gleevec is first choice for treating CML, and if he is doing good in every other way then encourage him that he is doing great. I hope this helps you. I would be glad to help you with any other questions.
Avatar f tn i get my heart checked every 2 weeks now and i am fine with the qt thing. i take the chemo pill called gleevec and have to force myself to eat so i dont get sick when i take it. how long will these withdrawel problems go on? i have xanax to take (1mg) but dont work to good. i should would appreciate any advice from any one on how to deal with these issues, family dr says its anxiety but i think its the withdrawels from the high dose of elavil.
397118 tn?1219762250 s sister comes out does her part, Don receives the transplant and is put on all the ordinary protocol drugs for GVHD and about a week after transplant he has a neurological allergic reaction to prograph. He was totally wacked out, hallucinations, jabbering, restless just a real nutcase, then he becomes nonresponsive to anyone and his breathing very irratically. They ship him to ICU where he codes and they put him in a coma and on a ventilator. This was on a Saturday.
1004138 tn?1316251113 No there is no herbal treatment for CML!!! Were you diagnosed with CML, and if so are you seeing a specialist and what treatment are you on.? I am being treated for CML, and was told not to even drink herbal teas well on my medication. Share some more information so I can help you. I have had CML for 13 years.
Avatar m tn Hey I had a bone marrow transplant two years ago and, on my doctor just told me that he will put me on steroids because my liver enzymes have been elevated and I just didn't take it very well. I am scared and I know there is nothing I can do to prevent stupid GVHD. I am so scared to start taking these drugs. Please help !!
Avatar n tn I am a Leukemia Survivor also. What type of Leukemia did you have, and what was your treatment. I have CML, and have achieved a major molecular response through a oral chemo drug called Gleevec. It does not sound like these patches have anything to do with the Leukemia. I would see a Dermatologist to have them evaluated. I hope that helps you a little bit.
Avatar m tn In the 2 months that followed she had 4 episodes of fever with rash showing up three times. Dengue and Malaria were ruled out by a blood test. The stem cell bank in question (www.reelabs.com) has given us a certificate of analysis claiming that they test for HIV 1 & 2, HCV etc via PCR before extraction of stem cells from cord blood.
Avatar m tn I should mention that I have CML but it has been in remission for the last two years and I am no longer taking Gleevec. I am scheduled to be looked at by a group that kills the nerve endings in the heart that causes AF but there is an 18 month waiting period. My question is how many times can I be cardioverted and what is the downside of having it so often?
225036 tn?1294509400 Lord, please give Becky the miracle you can do. She deserves to get a break Lord, and so does Ty. Hold her in your hands Father and let her feel you when she is down. In Jesus name, amen.
Avatar n tn * buprenorphine Metabolized into norbuprenorphine by cytochrome-P450 isoenzyme 3A4 * Tyrosine kinase inhibitors, including Gleevec and Tasigna, used to treat chronic myelogenous leukemia and gastrointestinal tumors.
Avatar m tn I was diagnosed w/CMML in 2009 and did 6mos of Vidaza. Monocyte levels keep rising and are now at 28%. 54 yr old male. My drs. just keep telling me to watch and wait, but I don't feel comfortable doing that, especially since I am fighting a recurrent staph infection that keeps returning every month.
Avatar f tn She then went to Mayo and the doctor there told her she did not have Leukemia based on her blood work there, but she had been overdosed on Hydrea during the summer to the point her wbc was 3 and was only recovered to 11 by the time of her appt in Sept. Now her wbc is 58 and her hometown doctor is putting her back on Hydrea. Her family is concerned she is going to take a serious chemo drug when there is still a question of what she has. Could it be an infection that isn't showing up?
419309 tn?1326503291 I appreciate the links, and thanks for looking out. I know nygirl still stops by, but I don't recall seeing alagirl in quite a while... I have to admit it makes me a little angry to see so many people who have had low hgbs go unnoticed. My husband's hgb is normally in the 13-15 range, so it's unbelievable how he's still functioning at <7.4. (The nurse missed both his 10 and his 9 back in Feb & Mar.
148588 tn?1465778809 Louis and the founder of Rare Genomics, a nonprofit organization that designs treatments for rare childhood diseases based on individual genetic analysis, “we have drugs that target specific cancer mutations. Examples include Gleevec, Zelboraf, and Xalkori. Vertex,” a pharmaceutical company based in Massachusetts, “has famously made a drug for cystic-fibrosis patients with a particular mutation. The genetic targeting of individuals is a little farther out.
962875 tn?1314210036 Watch Out For Interactions with Tamoxifen (Nolvadex) Breast cancer is the most common cancer in women and tamoxifen (NOLVADEX ) is used commonly in the treatment and sometimes in the prevention of this disease. In 2007, 1.7 million prescriptions were filled for tamoxifen. However, recent evidence suggests that certain other drugs can reduce the anti-cancer effects of tamoxifen, potentially increasing cancer recurrence and reducing survival.
Avatar m tn I was prescribed high doses of prednisone to tread Graph vs. Host disease (GVHD) and as a result have had to endure complete joint replacements. Right knee and left hip have been replaced, the other two are in the planning. I've been on pain medication for about 8 yrs. for one reason or another. I've been prescribed; Dilaudid, Methadone, Oxycodone, MsContin, Fentanyl and have weaned off, and back on, about 4 times in the course of 8 yrs.
Avatar f tn I am asking for my sister-in-law who had back surgery (single level fusion) 4 months ago and whose surgical site has not healed. I have had 4 back surgeries and all surgical sites healed in weeks, but hers continues to ooze a clear to amber liquid 4 months following the successful surgery.