The VA [ Veterans Administration ] has looked into using fluvastatin as a treatment for HSV with some impressive results. One patient had a 1/50th load count after 4 weeks of treatment. Some others showed dramatic reductions in load counts also. Has anyone out there tried this treatment ? It does have FDA approval as a treatment for high blood pressure. VA looking for effective treatment for drug resistant HCV infections.http://www.ncbi.nlm.nih.
Red yeast rice, which contains lovastatin, should also be avoided during treatment with telaprevir. Fluvastatin, pravastatin, pitavastatin, and rosuvastatin are probably safer alternatives, since they are not metabolized by CYP450 3A4. All patients treated with HMG-CoA reductase inhibitors should be advised to promptly report any unexplained muscle pain, tenderness, or weakness, particularly if accompanied by malaise or fever.
Accordingly, Plavix may interfere with the metabolism of phenytoin, tamoxifen, tolbutamide, warfarin, torsemide, fluvastatin, and many non-steroidal anti-inflammatory agents, but there are no data with which to predict the magnitude of these interactions. Caution should be used when any of these drugs is co administered with Plavix.
The message I get is that at very high dosage of Statin, maybe liver function should be monitored for liver patients. This agreed with my doctor's assurance about Crestor at 10mg. The case of acute liver failure I know of is suspected but not confirmed.
If you are going on a statin - which are safe for people with Hep C, by the way - you might consider asking for fluvastatin, which has been shown to inhibit HCV replication in vitro, and has the same efficacy and heart protection as lipitor or crestor.
Congrats on svr and Good luck!
There is currently a Phase II study going on with Fluvastatin along with regular SOC treatment and because Fluvastatin, like Alinia, is already an approved drug, it would be available sooner and more easily than the PI drugs, for example, currently in trial.
http://www.hepatitis-central.com/mt/archives/2008/04/fluvastatin_low.html
These links really made me sit up and take notice.
A year ago, my doctor gave me Lescol/Fluvastatin to take because I am a high risk for heart disease due to genetics and diabetes. At that time my Lipids were within normal range. After a month, ALT/AST results were very elevated.
and medication was discontinued. Since then, I've gone through ultrasound, HiDa Scan and finally diagnose of fatty liver. The Gastroenterologist recommended Liver Biopsy to check for liver damage.
Lipitor (atorvastatin), Lescol (fluvastatin), Mevacor (lovastatin), Altoprev (lovastatin extended-release), Livalo (pitavastatin), Pravachol (pravastatin), Crestor (rosuvastatin), and Zocor (simvastatin). Combination products include: Advicor (lovastatin/niacin extended-release), Simcor (simvastatin/niacin extended-release), and Vytorin (simvastatin/ezetimibe).
The new labels will warn patients about:
Memory loss and mental confusion.
The same enzyme also is responsible for the metabolism of phenytoin (Dilantin), tamoxifen (Nolvadex), tolbutamide (Orinase), torsemide (Demadex), and fluvastatin (Lescol). Although important interactions between clopidogrel and these drugs are unlikely, interactions should be looked for carefully.
You should consult your doctor to insure the degree of blood thinning is within specification with INR.
please let me know if the dosage i am taking i.e. 1/4 of 20 fluoxetine and 5mg olanzapine combo and 3/4 lorazepam is high or low.
83, The doctor has now increase my weekend dosage to 100mcg but I still feel this is not enough. I feel 125mcag along with 100mcg every other day would be more suitable for me. Please advise as I'm concern about about my baby.
76)
I was feeling a little bit hyper on this dosage. I was nervous, not sleeping , etc. I think that I seem to do better when my TSH is a little higher. I already had 100 mg of Synthroid, so I started taking the 100's, with the knowledge of my doctor, but by day 3, I was crying, emotional, and not feeling good at all. What does this mean? Was the 100 already not enough or should I try maybe alternating the 112 and 100, or does this mean that I need to stay on the 112?
If the doctor prescribed that dosage, then I would trust him/her. Zoloft is typically prescribed from 50-200mg, so your son is taking a 'normal' dosage in my opinion. I was on Zoloft a couple of years ago and had no major problems coming off of it. Just ensure when it is time to come off the medication work with your doctor and taper down slowly.
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