Duloxetine and liver injury

Common Questions and Answers about Duloxetine and liver injury

cymbalta

Avatar f tn There is a risk from duloxetine in general can cause kidney and liver trouble in some, drinking alcohol while on this drug increases this likely hood and if your a alcoholic then my advice is to have 6 month blood tests of your kidney and liver functions.
Avatar n tn I would not have recommend you to go onto duloxetine, in some, duloxetine can cause kidney and liver problems, drinking alcohol while taking this drug will unfortunately increase that risk and even more so with someone with your condition.
1008841 tn?1293598960 Because it is possible that Cymbalta/duloxetine and alcohol may interact to cause liver injury or that Cymbalta/duloxetine may aggravate pre-existing liver disease, Cymbalta should not be prescribed to patients with substantial alcohol use or evidence of chronic liver disease." "Then this year they started me Effixer..." Effexor is known to increase the risk of bleeding. If you have cirrhosis and portal hypertension you are already at an increased risk for bleeding.
217229 tn?1192762404 • Because it is possible that duloxetine and alcohol may interact to cause liver injury or that duloxetine may aggravate pre-existing liver disease, CYMBALTA should not ordinarily be prescribed to patients with substantial alcohol use.
Avatar m tn It is effective for major depressive disorder and it is as effective as venlafaxine in generalised anxiety disorder. It is well tolerated and is considered a first line treatment strategy. Duloxetine failed the US approval for stress urinary incontinence amidst the concerns about liver toxicity and suicidal events; however, it was approved for this indication in Europe and Canada.
Avatar n tn First thing to note, Unfortunately smoking does affects the amount of duloxetine in your system and blood stream meaning that you will loose between 40 - 50% of the duloxetine dose you take. It is not uncommon for people to have their duloxetine prescription increased if they smoke.
5055866 tn?1362951481 Unfortunately smoking does affects the amount of duloxetine in your system and blood stream meaning that you will loose between 40 - 50% of the duloxetine dose you take. It is not uncommon for people to have their duloxetine prescription increased if they smoke. Unfortunately it is not uncommon if you miss a dose to be experiencing these problems if your on a high dose, my patients even at a dose of 30mg do experience brain zaps, nausea and vomiting even with just one day missed.
1218873 tn?1300091216 First thing to note, Unfortunately smoking does affects the amount of duloxetine in your system and blood stream meaning that you will loose between 40 - 50% of the duloxetine dose you take. It is not uncommon for people to have their duloxetine prescription increased if they smoke.
20003388 tn?1515166040 In my research I also see that taking it with anything that inhibits liver enzyme CYP2D6 (which both Fluoxetine and Duloxetine do) can cause the levels of the medication to build up in the body essentially behaving like you have taken more than you have. My question is, would it be safe to add a very tiny dose, say, 3 mg as a sleep aid to my medications. If it builds up enough to mimic say 6 mg or 10 mg that wouldn't be too bad.
1580828 tn?1322128022 Unfortunately smoking does affects the amount of duloxetine in your system and blood stream meaning that you will loose between 40 - 50% of the duloxetine dose you take. It is not uncommon for people to have their duloxetine prescription increased if they smoke.
Avatar f tn I am taking DULOXETINE 60MG.
Avatar f tn I did take Duloxetine previously for pain (adjunct to the Celebrex) and it did help, but my GP is skeptical that Gabapentin would help even if combined with Duloxetine. Does anyone else have Osteoarthritis and is unable to take NSAIDS and have you found a medication that works? Thanks in advance for your replies.
Avatar m tn t remember when Cymbalta got FDA approval to extend its patent to cover pain control, but at that time the drug was reviewed and was found to cause liver problems. 18 people were found to have died, I believe, which means the number of people with adverse liver effects from this drug could be very high. The FDA just put out a warning about it.
Avatar f tn I think my anxiety attacks are pretty much under control since I take the duloxetine, and I really think with me taking Duloxetine and me completely stopping the vyvanse was why I didn't have a harder time coming off the medication.
446474 tn?1446347682 Food and Drug Administration (FDA) is warning that hepatitis C treatments Viekira Pak and Technivie can cause serious liver injury mostly in patients with underlying advanced liver disease. As a result, we are requiring the manufacturer to add new information about this safety risk to the drug labels.
1218873 tn?1300091216 i was prescribed pregabapentin and at only 50mg twice daily i become so drowsy i was unable to function- so gp weaned me back to 25mgs a day and asked pain clinic to review-- they then changed it to duloxetine which again at only 60mg, i am constantly sleeping and fall asleep anytime of day- he has now added in gabapentin 100mg, with the duloxetine and to increase to three times a day-- from what everybody says, this is about the same as the pregabapentin but with the duloxetine added.
Avatar m tn potential to increase liver enzymes and cause liver damage, patients must be monitored for normal liver function. At least, that's what the label used to say. Now the FDA has removed this long-standing warning and ruled that patients taking statins no longer need routine monitoring of liver enzymes, but instead can have liver enzymes tested before starting the drugs, and then only as clinically needed.
Avatar f tn probably it's important in what form capsaicin will be delivered
446049 tn?1649005835 I am starting on a very low dose of the cymbalta, so that I can transition off the first one, and onto this one. Both my new gyne and my psych want me to give this a try. Since I have at least another month or two wait before I can go to the pain clinic, I'm willing to give everything I can a try! Some people do get wonderful results from the reviews I've read on line, so I am crossing my fingers I get the same results! My next step would be Neurontin.
8170270 tn?1413845335 I was diagnosed with Hashimoto's this last December and have been on Synthroid 25 mcg since. I've gone in several times to have the levels checked Because I'm still not feeling well (fatigue, sleepless, brain fog, itchy irritated skin, joint pain etc) while my thyroid function came back within normal range I had "concerning" elevated liver enzymes and am getting an ultrasound. My question is are liver issues and Hashimoto's related? Is this typical?
Avatar m tn Outcome and Management The liver injury linked to tadalafil has been self-limited and resolving within 2 to 3 months. There is no known cross-sensitivity between tadalafil and the other PDE5 inhibitors currently in use in the United States, but switching to another PDE5 inhibitor should be done with caution.
1714930 tn?1319644573 Congratulations on your SVR... Does anyone know how long it takes for our Liver to recover 100% back to normal after SVR? --------------------------------------------------- Debra.. It might be a stretch to assume that once you have eradicated the virus that the liver will regenerate to 100% with absolutely '"nill scarring" ..
Avatar f tn I was on that for several years and did better than anything else but my neuro wanted me off it, so I agreed to go with the Duloxetine. There are options.