Some of the alternatives include aspirin, Clopidogrel (Plavix), ticlodipine (Ticlid), dipyridamole (Persantine). Another alternative is Heparin injection. Different situations require different levels of anticoagulation. It is important to discuss the best treatment option with a physician.
As you have been stable on these medications, your doctor has suggested you continue with the same. Aggrenox has both aspirin and dipyridamole extended release. Persantine is dipyridamole, but you will have to get extended release tablets as the two asprin and dipyridamole should not be taken together. Don’t change the medications without discussing with your doctor. So, consult him and then decide.
Hope this helped and do keep us posted.
Pharmacological stress Tc-99m MIBI scan was performed with Dipyridamole given at arate of 0.14 mg/Kg/min over 4 minutes followed by injection of radio tracer 6 minutes later.
Findings are: Peak stress images revealed hypoperfused infero-septal and apical segment, which showed reversal at rest.
Impression: Findings are consistent with infero-septal and apical reversible ischemia.
Thanks all!
I ask the Cardio Doc about the dangers of the Persantine stress test, he say that the Persantine drug dont stimulate the heart in the same way than the Doputamine and that I will feel weak, will have headache cause of the vasodilation (already have chronic headache), a drop of blood pressure and small increase of the heart beat, he said it's an easier test with less side-effects than the Dobutamine test and more accurate since it's a nuclear imaging test, who is better than the usual e
His ECG shows that he has a right bundle branch block configuration. A Persantine MIBI scan showed evidence of ischemia. He had a pulmonary function test which showed moderate interstitial lung disease. The patient was brought in and catheterized by myself to exclude any possibility that his shortness of breath may have any cardiac component to it. He had grade I LV function with a normal RCA, LAD, and circumflex. A full hemodynamic assessment was made and his cardiac output was 6.
The adverse effects experienced are similar to those with use of adenosine. While adverse effects are less frequent with dipyridamole (47% of patients), they tend to be more serious than those associated with adenosine. The most common adverse effects of dipyridamole are chest pain (19%), headache (12%), and hypotension (4.6%). In addition, 12% of patients require aminophylline for reversal of adverse effects.
Dipyridamole was infused coupled with low level excercise without any significant complaints and ischemia ECG changes. heart rate changed from 68 to 100/min and blood pressure from 130/80 to 140/90 mm of HG.
Findings:
Images acquired after stress injection of Tc-99m-MIBI showed markedly reduced to absent tracer uptake at apex,antoseptal wall,apical anterior segments and almost whole of the inferior wall.
What is nonreversible apical inferior wall and what does it mean when they say no dipyridamole-induced reversible ischemia .there is mild defect in the apical inferior wall that is not reversible at rest.
While you are taking Aggrenox (aspirin/dipyridamole), you should avoid taking over-the-counter pain medicine, especially any other products containing aspirin or non-steroidal anti-inflammatory drugs (NSAIDs).
Also, Avoid alcohol, or drink a minimal amount, as the combination of Aggrenox and alcohol could cause stomach bleeding.
My results of Persantine Nuclear Scan: Stress and Rest Perfusion images demonstrated moderate sized mild severity partially reversible mid anterior perfusion defect. Raw images demonstrated evidence of breast attenuation. Resting end-diastolic vol is 93mls and post stress is 101. Resting end systolic vol is 32mls and post stress is 35mls
What does this mean? What can I expect? My doc wants to do a cath, is this necessary?
After, she was told she could never take Coumadin again. She was placed on Persantine (This medication is used in combination with "blood thinners" to keep clots from forming after heart valve replacements. Dipyridamole (Persantine) belongs to a class of drugs known as platelet inhibitors. It helps to keep blood flowing by stopping platelets from clumping together and by keeping heart blood vessels open.
Blood-thinning medications -- Ginkgo has blood-thinning properties and therefore should not be used if you are taking anticoagulant (blood-thinning) medications, such as aspirin, clopidogrel (Plavix), dipyridamole (Persantine), heparin, ticlopidine (Ticlid), or warfarin (Coumadin). There has been bleeding in the brain reported when using a ginkgo product and ibuprofen (Advil), a non-steroidal antiinflammatory drug (NSAID).
There is suggestion of mild left ventricular chamber dilatation with Persantine stress, in particular, with a TID inde of 1.15. This is a nonspecific finding and may or may not reflect some underlying multivessel coronary artery disease. There is no significant regional wall motion abnormality identified. There is question of incomplete myocardial wall thickening in basal portion of the inferior wall on the cine study.
Hello All,
I just came back from my doctor and he told me the results of both Nuclear Mibi and Echocardiogram. Nuclear Mibi showed nothing ,No heart damage and no CAD.Echocardiogram showed some sort of fatty inside heart around the backwall or closer which doctor needs to examine further and he will do further testing like looking into my heart etc etc. He terms it as Pallicardium which I googled and nothing came up like the term does not exist .Maybe I am spelling it incorrectly.
I suffered a mild stroke (blood clot) Consultant prescribed Clopidogrel but cannot tolerate side effects. Then consultant prescribed Dipyridamole. I cannot tolerate this either. Severe headache, vomiting and diarrhoea. Has anybody got a different medication they are on?
Symptoms are as follows,
- Anxiety when falling asleep
- Tightening through arms and chest
- Arrhythmia at times
- Low blood pressure
- I was startled like my blood is going to stop circulating
- jolt out of bed feeling like I am going to faint, this causes my heart to race,
I am awaiting an Angiogram, my cardiologist swears I am fine, but want this test to rule out the Ischemia found on my Mibi test.
Patients who are taking medications for lung problems, diabetes mellitus, congestive heart failure and Persantine may need to alter their medications.
Symptoms are as follows,
- Anxiety when falling asleep
- Tightening through arms and chest
- Arrhythmia at times
- Low blood pressure
- I was startled like my blood is going to stop circulating
- jolt out of bed feeling like I am going to faint, this causes my heart to race,
I am awaiting an Angiogram, my cardiologist swears I am fine, but want this test to rule out the Ischemia found on my Mibi test.
ECG, 24hr Holter, MIBI and Echo, during MIBI it was determined though that I do have excercise induced LBBB. Was put on BP meds 180mg once a day Tiazac, had helped a bit, chest pressure is less, heart rate has diminished at times - but not consistant. Blood work all fine except verry low ferritin, I've been taking 900mg iron daily. I was also tested for pheocromocytoma (tumor in adrenal glands) will get results tomorrow.
It was recommended because she had a reversible inferior apical defect on a Cardiolite discovered during a persantine stress test. The doctor said she was not a candidate for open heart surgery because she also has significant COPD, Diabetes and Asthma.
My question is: What does this mean? The cardiologist said he wouldn't do anything at this time.
ECG last month showed SVES, RBBB. This week he has stress test with dipyridamole protocol, and injection of thallium-201. The result showed "evidence of mild, small to medium size, irreversible perfusion defect in the inferior/inferolateral wall (mid to basal level)." Could you explain what this means? Does he need to have surgery or pacemaker? thanks in advance for your help.
STRESS EKG PORTION: Patient underwent Persantine PET protocol for 4 minutes and heart rate rose to 55% of the maximal age predicted heart rate. Stress EKG portion was non-diagnostic for ischemia.
FINDINGS: Stress perfusion images show a mild reduction in uptake in the distal anterior wall and apex with normalization on resting images. This is suggestive of mild ischemia in the distal left anterior descending artery territory.
Which diagnostic test would be best to test for artery blockage the thallium or the MIBI? or should I start with a stress echo? I have had some minor chest pain, a dull pain down my left arm, and some upper central back pain. I don't want to wait until I have a heart attack. My 75 year old dad just had triple bypass surgery last week after an MI. Thank you!
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