diclofenac and liver

Topical Diclofenac Labeling Updated to Match Oral Agents ... : Treatment with all products containing diclofenac sodium, including Voltaren Gel, may increase liver dysfunction, resulting in severe hepatic reactions and liver ... www.medscape.com/viewarticle/713451 I would definitely not take it!

Acetaminophen can be very toxic to the liver. Taking it and alcohol together can cause severe liver damage. If you have liver disease, NSAIDs (non-steroidal anti-inflammatory drugs), like Advil (ibuprofen) can also be dangerous to take. Aspirin should also be taken with care because it can lower a person's platelet count. People with liver disease often experience a swelling of the spleen. This can destroy platelets faster than the body can make them.

My 59 year old husband, Hep C+ diagnosed in 2007, F-4 Cirrhosis diagnosed in 2010, compensated liver (last blood work was in July, 2012, and he has never had ascites, varices, or hepatic encephalopathy), and failed three Hep C treatments in past 5 years (last failure was triple tx w/Incivek stopped treatment mid-April, 2012 due to viral breakthrough), not currently on treatment. Question: He has had pain and selling on forearm recently.

The FDA just announced that dicoflenac gel (brand name Voltaren Gel) often prescribed for arthritis pain is linked to severe liver damage and it can happen within the first month of use According to the FDA, this topical gel has been reported to cause liver necrosis (death of liver cells), jaundice, and liver failure some cases of which have required liver transplant and some that have been fatal! Despite these horrible side effects, dicoflenac gel remains on the market.

I knew something was wrong. Went to the doctor and the blood lab showed really high levels of liver enzymes and bilirubin. The doctor prescribed me ursodiol and referred me to a liver specialist. I was diagnosed with Hep C 14 years ago and I did pegintron and ribavirin for a year but I relapsed. My liver levels two years ago were normal. How can this happen? I have been in Diclofenac (Naproxen) medicine for 3 1/2 months as result of a foot injury.

However other important causes are fibrocystic breast disease,ductal ectasia, mastitis(inflammation of breasts),galactoceles,benign and malignant pathologies of breasts, referred pain from liver or musculoskeletal system,arthritis of the ribs, costsochondritis and inflammation or sprain of pectoralis muscle. I feel that an examination by a gynecologist will be the best if the symptoms persist for long.

I tried Mobic and Nabumatone and had problems with upset stomach and headache. In addition to Fibromyalgia I also have arthritis in my spine and shoulder, so I take it for that and I can't live without it. Ibuprofen and Naproxen doesn't even touch the inflammation and pain.

Yes, I do use this medication, however my RA doc has me make it up into a cream and use it topically instead of swallowing them and risking stomach and intestinal damage. Diclofenac is a rather old, but good good antinflamatory NSAID medication that really can ruin your stomach which is why they don't prescribe it much anymore. I know it may sound strange but it works really well.

Question. I have started taking Diclofenac 75mg x's 2 a day to try and see if a non narcotic medication may give me some relief long term with my rib pain. I have taken it for 2 weeks and at first I didn't think it was helping at all. Now I think 1 of 2 things either A) it's starting to build up in my system and is helping better or B) My ribs just happen to feel a bit better lately.

i have taken diclofenac for over 20 years with no side effects i have had to come off the tablets 75mg x twice day 4 days ago as I am showing some drying of kidneys from another mediation to ensure it is that one i have come off anything whih might affect me.

All the regulars here know me, but a brief intro for others: I 'm 58, have had HCV since 1984 and was dx'd with compensated cirrhosis around 2004. I'm now near the end of my third tx, a 48-week bout of triple tx with Incivek. I've been UND and had normal liver enzymes since week 8 and I'm now on week 46. Here's my new question: I've had autoimmune arthritis for decades now, but in just the last year I've also developed osteoarthritis in both thumbs.

Patients who take these medications (regularly or daily) should undergo monthly laboratory testing for the first three months of therapy and then every three to six months because of the association between these medications and liver disease.

I was put on antibiotics for a week on day 4 and booked in for an ultra sound. I was also given diclofenac to help with the pain. Avo upper data later the pain did not get better. I went back to the doctors and they weren't sure it was a kidney stone. Occasionally pain worsened on some days. Was prescribed codeine for when I needed it. I continued having pain and was signed off work. I only had fever on day 2. Had my ultrasound and nothing was found: no stones, no cysts or swelling.

Other important causes are fibrocystic breast disease,ductal ectasia,mastitis(inflammation of breasts),galactoceles,benign and malignant pathologies of breasts,referred pain from liver or musculoskeletal system,arthritis of the ribs,costsochondritis and inflammation or sprain of pectoralis muscle. I feel that an examination by a gynecologist will be the best.

Other important causes are fibrocystic breast disease,ductal ectasia,mastitis(inflammation of breasts),galactoceles,benign and malignant pathologies of breasts,referred pain from liver or musculoskeletal system,arthritis of the ribs,costsochondritis and inflammation or sprain of pectoralis muscle. I feel that an examination by a gynecologist will be the best.

She had no idea what it was and did some blood work for my liver and also white count. My liver test came back with a protein slightly elevated. She is having more test done and I'm still wating to hear. Anyone have a clue??

You are correct. The usual interactions suggest a decrease in levels of the other drugs taken with carbamazepine. Try searching for 'carbamazepine metabolism' and 'diclofenac metabolism'. It shows that both meds are metabolized by CYP3A4. Diclofenac may decrease levels of CYPA4 (search 'diclofenac inactivation CYP3A4); this could potentially lead to increased levels of carbamazepine.

Other important causes are fibrocystic breast disease,ductal ectasia,mastitis(inflammation of breasts),galactoceles,benign and malignant pathologies of breasts,referred pain from liver or musculoskeletal system,arthritis of the ribs,costsochondritis and inflammation or sprain of pectoralis muscle. I feel that an examination by a gynecologist will be the best.

The effects of cholestyramine and colestipol on the absorption of diclofenac in man.Colestipol produces a similar but smaller effect. Though some information charts say that it should be used with caution in patients with Diabetes,it refers to underlying conditions as renal failure, hepatic impairment,IBS,stroke,clotting problems,asthma, allergies, CD/colitis,HTN,smoking,High LDL/HDL etc are present in your history. So donot worry about anything.

Other than that, other important causes are fibrocystic breast disease,ductal ectasia,mastitis(inflammation of breasts),galactoceles,benign and malignant pathologies of breasts,referred pain from liver or musculoskeletal system,arthritis of the ribs,costsochondritis and inflammation or sprain of pectoralis muscle. I feel that an examination by a gynecologist will be the best.

Other important causes are fibrocystic breast disease, ductal ectasia, mastitis(inflammation of breasts),galactoceles, benign and malignant pathologies of breasts, referred pain from liver or musculoskeletal system, arthritis of the ribs,costsochondritis and inflammation or sprain of pectoralis muscle. I feel that an examination by a gynecologist will be the best.

Hello, The various causes of breast soreness are fibrocystic breast disease, ductal ectasia, mastitis(inflammation of breasts),galactoceles, benign and malignant pathologies of breasts, referred pain from liver or musculoskeletal system, arthritis of the ribs,costsochondritis and inflammation or sprain of pectoralis muscle. I feel that an examination by a gynecologist will be the best.

however there are a number of diseases and conditions that cause them to spill from the liver into the bloodstream. Through blood testing doctors can determine the type of enzymes, make a diagnosis and determine the need for any additional testing. In essence, the ALT blood test evaluates how well your liver is working. The ALT test was formerly called serum glutamic pyruvic transaminase (SGPT).

//www.drugs.com/voltaren-gel.html. Diclofenac is voltaren and the gel contains the Nsaid. This information states clearly that aspirin should not be used at the same time. Normally, blood thinners are also not used with Nsaids. So, speak with your doctor, of course, but would advise not to use these together based on the provided information.

There may be reasons why, for you, she is suspecting the Diclofenac and not the other. Give her a call and ask. Let us know what happens. I'm glad you're feeling better though - it must have all been pretty scary. I have allergies to some meds, but it's all skin reactions, not breathing stuff. I imagine that's terrifying.

Other important causes are fibrocystic breast disease,ductal ectasia,mastitis(inflammation of breasts),galactoceles,benign and malignant pathologies of breasts,referred pain from liver or musculoskeletal system,arthritis of the ribs,costsochondritis and inflammation or sprain of pectoralis muscle. I feel that an examination by a gynecologist will be the best.

Diclofenac and liver

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