I also took Xifaxan simultaneously
for the IBS 500 mg 3 times daily
for 10 days. The
Cipro seemed to help the joint pain but the two compounded the GI symptoms. I started having allergic type reactions to every food I ate, presumably an immune response to increased permeability associated with gut irritation. After I finished the Cipro, the joint pain returned along with some mild urethral irritation. I am allergic to Flagyl, so from what I've read my next option will be doxycycline.