Navelbine, or vinorelbine, is a chemotherapy that has been found to have good activity in treating metastatic breast cancer. It has been studied on its own and in combination with other chemotherapy medications. It also has been studied in combination with herceptin for treatment of metastatic breast cancer.
The treatment is relatively well tolerated. The most serious side effect is neutropenia (decrease of white blood cells) that can leave one more susceptible to infection.
A recurrence is the re-emergence of the same cancer at the same site, whereas a metastatic cancer is the spread of the cancer via blood, lymph or direct contact to other organs of a patients body. There are other differences as well on the basis of the danger and the treatment levels for the two.
Let us know if you have any more queries.
Good luck once again.
TI had the Invasive Lobular and the metastatic area was on the right side of my breast (arm pit side) and in the lymph nodes.
Even though the path report says: ' metastatic disease in axillary tct, extranodal.' that does not mean that your cancer has progressed to stage 4, or metastatic cancer. It said the same in my surgery report, and the word 'metastatic; was also used. my cancer was a 3C.
If you do have cancer, there are still a lot of chemotherapy options for you even if you have heart disease. One of the drugs frequently used for breast cancer - Doxorubicin - can aggravate an existing heart problem, but this drug can be replaced by similar drugs (e.g. Epirubicin) with less adverse effects on the heart. Another option would be to use classes of drugs which are entirely different from Doxorubicin and which are relatively safe for the heart.
My mother just got his breast removed. We have just received the surgical pathology report. It says:
Diagnosis: Left breast:
1. Infiltrating ductal carcinoma grade II on a scale of I to III according to modified Bloom and Richardson grading system.
2. Size of lesion: 3.5 x 2.5 x 1.5 cm.
3. Lesion is 0.2 cm from deep margin.
4. A small focus of lymphatic invasion is present which is 0.1 cm from deep margin.
5. Nipple and areola: Tumour free.
6.
There is really no point in scanning every inch of your body for metastatic cancer, because absolutely no test will pick up micro, or very small, cancer cells. So, the chemo is both curative and preventative.
just because your cancer has spread to your lymph nodes that does not mean you have metastatic, or stage 4 cancer.
like yours, my cancer was also described as metastatic because of the lymph node involvement.
Stage 3 & 4 Forum (which you can click on under the "Related Communities" heading to the right of these posts, may allow you to connect with others in your stage.
Also, a doctor's reply to a post by Birdies, "Triple Negative Treatment Options," dated 1/3/08, in the Breast Cancer Expert forum, discussed TNBC.
Best wishes...
She had two small tumors in her right breast. She had them removed and they found cancer in 2 out of 20 (or 28- not sure) lymph nodes. I'm not sure if the cancer was Stage II or III, but I'm assuming it was Stage II because they weren't suree at first if she would even need chemo. I don't know much else except that the cancer if "hormone fed" and she is on tomoxaphin (spelling?). I apoligise for my lack of knowledge.
Anyway, she was done with chemo and doing great.
Her oncologist, however, has told her that they believe it is metastatic breast cancer due to her symptoms and some elevated levels in her blood. I hope they are wrong. I have heard though that although metastatic breast cancer cannot be cured that it can be treated and you can live a long life with it.
It is given to postmenopausal women with hormone responsive breast cancer. It can be given in the adjuvant or metastatic setting.
Take care.
You're right - ovarian cancer does not get the recognition it needs. It's the cancer that "whispers." The symptoms are generally vague and doctors may write them off as stress or bowel problems. Too often the symptoms are ignored until it's too late.
The women on this forum have been fighting for public recognition of this disease, to raise awareness. You'll see pink ribbons and pink yogurt tops all over the place but you won't see teal any where.
Dear, it is actually called Metastatic breast cancer as it has metastasized to other areas of the body. This is not a good thing, and does require surgery, but there is no rush that two or three days to catch your breath wouldn't matter.
2cm poorly differentiated invasive ductal carcinoma), left axillary lymph node (metastatic carcinoma in one of three lymph nodes) and left breast sentinel node (no tumor seen). Path report states the following:Histologic type: IDC, Total Nottingham Score Grade III, pT2, pn1a: metastasis in 1 to 3 axillary lymph nodes, extracapsular nodal extension present, pMX, margins uninvolved by invasive carcionoma. ER - 0%, PR - 0%, Ki-67-91%, and HER-2/neu - 2.7 (overexpression).
You should see a surgeon who is experienced with cancer. The lump isn't necessarily cancer, but there are all sorts of cancer possibilities. For example, this could be Hodgkins Disease or a metastatic deposit from a primary tumor somewhere else in the body such as the lung. Don't forget that males can have breast cancer too. Have there been any changes in your left nipple? If so, breast cancer should certainly be ruled out.
I just got my wire-guided excisional biopsy results yesterday. the tumour is located way back near the chest wall: invasive adenocarcinoma tubular, 1.1cm, grade 1, excision margins clear, estrogen pos+++, greater than 90% of invasive cells; progesterone. pos+++, approx. 10% of invasive tumor cells; HER/2 neg. Ductal and lobular carcinomas are in situ. The breast surgeon plans to do a sentinel node biopsy at the same time on May 5th.
Tamoxifen is a hormone therapy used in hormone responsive breast cancer either in the adjuvant or metastatic setting. Tamoxifen can be used by both premenopausal and postmenopausal women. In premenopausal women, tamoxifen will not make the patient menopausal. The ovaries will still continue to produce estrogen. This is where the role ovarian ablation plays.
Dear lynn25, The pathology report shows basically that cancer was removed from the breast. There was also a cancer found in one of the lymph nodes tested. The oncologist will use this information to help to determine what will be the next course of action within the context of your individual situation.
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