With both diseases treatment for hep c with the standard drugs often worsens the autoimmune hepatitis. The autoimmune hepatitis is the result an immune response and interferon stimulates the immune system. And if you treat the autoimmune hepatitis then the immune suppressive drugs may worsen HCV. This makes it very difficult to treat or maybe "manage" would be a better word.
Autoimmune Hepatitis causes an elevated IgG. I found the following information on line:
Autoimmune Hepatitis: Diagnosis
Indications for Testing
Persistently elevated alanine aminotransferase (ALT) or aspartate aminotransferase (AST) 5x normal in the absence of any other cause of liver disease or damage
Criteria for Diagnosis
Diagnosis of exclusion – need to rule out other etiologies of liver disease, including toxins, infections, and hereditary diseases
Serum IgG >2.
Last March I went to the doctor because I was having low grade fevers, muscle weakness, and flu-like aching. Blood tests showed normal CBC, LFT's, and electrolytes, positive ANA of 1:640, positive LKM1 antibodies, positive antibodies for prior EBV and CMV infection, high morning blood cortisol, negative anti-DNA, SSA, SSB, Scl-70, cardiolipin, negative hepatitis viruses, and normal 24 hr urine cortisol.
how did they determine the autoimmune hepatitis from hep c? I have multiple autoimmune diseases, and I think I have the autoimmune hepatitis, but they said I tested positive for the hep c antibody, tested me a aweek later and said I was in remission.
This is a hepatitis C forum. Autoimmune hepatitis is a very different disease with different treatments. It might be better to discuss this with your treating doctor. Wishing you the best.
Would early detection and treatment of autoimmune hepatitis make a difference in the progress of the disease?
Autoimmune Hepatitis in not caused by a virus. It is caused by your own immune system attacking your body. There is NO way that you can 'catch' this from your husband. However, there is a possible genetic factor with the disease, so your children 'could' be at risk, but this is something that doctors aren't sure about, as I understand it. Hope this helps.
Hello. I was diagnosed with autoimmune hepatitis approximately 7 years ago. Shortly after that, I was also told that I had Hepatitis C. At that time, I was prescribed azathioprine (Imuran), and I took it for nearly two years which helped bring my ALT and AST levels down to normal levels. Also in that time, my sed rate was high (in the 100's), my titrate was 1:640, positive, and homogenous (it may have been homogenous/speckled, but I don't remember).
Ebstein Barr .....a positive IgG with a negative Igm means previous EBV infection (If both were positive that would mean current infection). High levels of IgG may be present and may persist at that concentration for the rest of your life.
The ferritin level is high (1492). Normal for a female is 12-150. This test shows higher than normal levels of iron in the body. It can be caused by hemochromatosis, a genetic iron overload disease.
There is a forum titled Autoimmune Diseases which includes Autoimmune Hepatitis. You may want to try posting your question on that forum. This forum deals primarily with hepatitis c.
My sister is 25 years old and suffering from disease and autoimmune hepatitis 2 months of the drugs used to suppress the immune system and I want some information about the disease and its treatment have ways
My mother was diagnosed with Autoimmune Hepatitis on first week of March 2009 by one of the Doctor (MD, DM – Gastro) in Mumbai.
My mother has undergone liver biopsy and several tests. Liver biopsy and some of the test results are reported below which shows suggestive Autoimmune Hepatitis (detailed report is attached with this email):
Liver Biopsy: Chronic hepatitis with onset of cirrhotic changes; HAI score 3 + 3 = 6, Suggestive of autoimmune hepatitis.
His sonography suggested fatty liver, his endoscopy suggested hernia and all the blood test were normal except autoimmune hepatitis. Here in one of the tests, LC-1 (cystosolic antigen) was borderline positive. Can anyone explain me what does that mean.
I had heard of all kinds of hepatitis, but not autoimmune. Not sure of its relevance but I had severe cholestasis when I was pregnant with her.
Thank you for whatever information you can provide.
Hepatitis C can lead to autoimmune hepatitis in a minority of patients. But most people who have autoimmune hepatitis don't have Hep C. Autoimmune hepatitis is caused by your immune system attacking liver cells and causing liver damage. Hepatitis C is caused by a virus.
Re: lab work....
The glucose...blood sugar is elevated but if the test was not done fasting then it means nothing.
I am regularly using Ventloin, Fomertrol+budesonide and Motelukast+LC. The only problem is breathlessness arising from throat tightness. I never wheeze in the life. The throat tightness is getting reduced when i take Ventolin. The doctor say i don't have to take ventolin beacause Fomertrol+budesonide and Motelukast+LC. will prevent the difficulty. But only medicines which seems to be working is Ventolin and Motelukast+LC.
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